Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000234
Karyotype Trisomy 18
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue Maternal uterine
Cell Line Prenatal chorion villus cells
Platform GPL570
Accession GSE6283
GEO Title Specific transcriptional changes in human fetus with autosomal trisomies
PMID 18253026
Article Title Specific transcriptional changes in human fetuses with autosomal trisomies
Author Altug-Teber O, Bonin M, Walter M, Mau-Holzmann UA, Dufke A, Stappert H, Tekesin I, HeilbroNoner H, Nieselt K, Riess O
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6283
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/18253026
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE6nnn/GSE6283/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1007_s_at 0.912297827776753 0.153972104276448 0.391947359944747 0.77521393956223
1053_at -1.25481978753152 -0.607315421454656 0.2498148843431 0.687853708971735
121_at -0.282260077180282 -0.0348794142323161 0.78590730934554 0.939403670327219
1294_at -0.937146883238339 -0.231283118114914 0.379881042881817 0.767917660418337
1438_at -0.226829758429372 -0.0273160637358183 0.827037965950659 0.950582661356713
1487_at -0.38726168329888 -0.0634280927291098 0.710067481785355 0.914092280133449
1494_f_at -0.657964025088769 -0.0699699484230303 0.531595341271807 0.845977224925805
1552256_a_at -1.89023758339314 -0.544426115153833 0.100640213372529 0.525889958538499
1552257_a_at -0.599710218641186 -0.188326856977756 0.567596085354498 0.859944443582641
1552263_at -0.839674059622175 -0.242527897903667 0.428833142742145 0.793908840699423
1552264_a_at -1.60053536359603 -0.489387251740054 0.15351325795256 0.595522605309936
1552274_at -2.15831123563731 -1.04005179698914 0.0677767304726797 0.462514113937364
1552275_s_at -2.6870714984008 -1.48801611446437 0.0312178465373771 0.361814311353828
1552277_a_at -0.599187829894433 -0.247070925512574 0.567925324742195 0.860285210813426
1552278_a_at -1.13359529442533 -0.116059209903162 0.294290833147517 0.720522469770969
1552281_at 1.04911984709282 0.128691615213073 0.328988497416114 0.74182078677778
1552286_at 0.951880011228944 0.169626512406281 0.372860072192924 0.763822060466181
1552287_s_at -0.451264041973189 -0.150448261049944 0.665447432990241 0.897925139056244
1552288_at -0.819615969416692 -0.0988842096386255 0.439446145843277 0.798583552402271
1552289_a_at 0.380630624216283 0.0570099196952145 0.714764903166486 0.916306159222514
1552291_at 0.302604940983725 0.0692391548884697 0.7709850538847 0.935086794968666
1552295_a_at -0.678410057999366 -0.288514805499978 0.519301818478746 0.839560088716931
1552301_a_at -2.30907615860264 -0.291716218706273 0.0542605957229577 0.429978530789127
1552302_at -0.221729715589653 -0.0267252698583347 0.830854031583633 0.951442660204181
1552303_a_at -0.359146297149487 -0.0582437286973443 0.730074687403437 0.920974748879158
1552306_at 0.388642918882955 0.167730671479135 0.709090708827528 0.913797343435302
1552307_a_at 1.20204279683415 0.35786761027919 0.268428534381507 0.701206310133114
1552309_a_at -0.670840962207281 -0.215215585179375 0.523831820065547 0.841991504515531
1552310_at -1.18125763649171 -0.254280437684899 0.276073527776818 0.70578258116972
1552312_a_at 3.75503707574717 0.570782916299106 0.00712100766987684 0.209176635009215
1552326_a_at 1.72523667321859 0.187552333227708 0.12813607851472 0.564311448022167
1552329_at -3.3491066295375 -0.50901841240188 0.012265750374502 0.263685080221451
1552330_at 3.86027983324602 0.690085719920826 0.00620924811859755 0.195845638181236
1552335_at 0.228837778412128 0.0257779175276731 0.825536848795874 0.9501950684727
1552344_s_at 1.06897145273112 0.334788395958106 0.320553014609987 0.735682219079199
1552347_at 1.56941111649202 0.340295877963863 0.160542092515808 0.603375691419399
1552355_s_at 1.38658064073521 0.143114689129212 0.208122662253738 0.651482935570377
1552360_a_at -1.8340482114614 -0.215085515881661 0.109294750898074 0.537185296668932
1552364_s_at -0.490540792195944 -0.0777929579176075 0.638753179547552 0.888753850737603
1552365_at -0.970543378668105 -0.426135254135856 0.364108174381342 0.759912845158118
1552367_a_at -0.714396214737672 -0.11456484549621 0.498106598267715 0.829651016975615
1552370_at -0.74546442150167 -0.485006765209741 0.48026808523112 0.818716464934509
1552375_at 3.99171812473333 0.292075860224765 0.00524494287444683 0.185036705593857
1552378_s_at 5.31559657094052 1.26375115851299 0.00110452796352536 0.0912505485564125
1552388_at 2.39837819308905 0.329601939758728 0.0475793930682338 0.411872835375675
1552389_at 0.627673257170647 0.0625965590391222 0.550137018745895 0.854770778152767
1552399_a_at -1.03306628172201 -0.129676279843133 0.335938228606639 0.744964980854455
1552411_at 0.850486110641591 0.100490336014295 0.423188629236091 0.791375745383226
1552412_a_at 1.41676249832676 0.152812961727585 0.199482996337709 0.643690462578057
1552417_a_at -1.18329652484276 -0.457355467052833 0.275315632940062 0.705141855127621
1552423_at -1.39545741313488 -0.353300642752905 0.205547738155449 0.648385744953782
1552426_a_at 0.16804688300753 0.0232199386223737 0.871298592037643 0.963860762441795
1552457_a_at -2.21288895280061 -0.37405554380774 0.0625300544074927 0.450292464986307
1552467_at 0.980496474615695 0.0987982321235279 0.359505554186572 0.757782388104617
1552470_a_at -2.07536867218921 -0.28522841091787 0.0766071604035738 0.483437744853244
1552472_a_at -0.428610183925146 -0.0612362317170225 0.681087409253778 0.903227773748905
1552474_a_at -1.48265472201074 -0.497119630567829 0.181728175627408 0.626391007786165
1552476_s_at -1.21788533640616 -0.359195190289013 0.262721691990173 0.697146519512232
1552481_s_at 1.68292777960985 0.688487654278808 0.136266838319092 0.575023378219621
1552485_at -3.19311592180294 -0.789776867695997 0.0152106191319904 0.283509328340021
1552486_s_at -2.95778904469947 -1.09259850442182 0.0211713982014773 0.316451816188303
1552487_a_at -1.52606075472128 -0.92146090793865 0.170827789722045 0.615928172592662
1552489_s_at 1.31376976931355 0.249708431924973 0.230340528698532 0.670970607706649
1552496_a_at 0.315690949717229 0.0409738472685248 0.761441114591304 0.931870215517668
1552501_a_at -0.0990294639328755 -0.0170900200851847 0.923891141743979 0.978497755245714
1552508_at -1.34030516278781 -0.372924163090091 0.222013498021264 0.664711331680958
1552515_at -1.06987718899251 -0.0791210841793117 0.320172304262011 0.735421408593038
1552518_s_at -0.775452286342734 -0.240742293246203 0.463459612630187 0.810972648669009
1552535_at -0.551823756338921 -0.0704683725510948 0.598236033605891 0.87249297175847
1552540_s_at -1.46076791782202 -0.196941882050656 0.187460872300861 0.630902067638413
1552541_at 1.47991602404755 0.124668955172524 0.182436709400568 0.626933902201349
1552546_a_at -1.02671162222023 -0.590004970563891 0.338721021710271 0.746619003779517
1552549_a_at 0.421600365134435 0.0642626808741902 0.68596166882647 0.904567022213531
1552553_a_at 0.528546075380828 0.0567979771582912 0.613457888172295 0.878974685017799
1552558_a_at 0.79238222253877 0.115830737760989 0.454149478115401 0.805288714611662
1552573_s_at 2.00211380144754 0.285631608805241 0.0853528273724909 0.499281127727771
1552575_a_at 1.13308873318483 0.129860818161403 0.29448964740019 0.720723242543186
1552580_at -1.7619239824818 -0.164757534741564 0.121460620264898 0.555265979734357
1552586_at 3.11395247479564 0.341194758389324 0.016986913995479 0.292109351316169
1552598_at 7.45085243115612 0.319202419246596 0.000143115673169007 0.0420957664003854
1552610_a_at 2.50948051563064 0.413074166805268 0.0404276226445842 0.390815566727362
1552611_a_at 1.28571190676695 0.263312146552767 0.239439573285589 0.677887677158275
1552612_at -2.06157704996189 -0.409853818178228 0.0781828755880712 0.486900384849463
1552613_s_at -0.507887712374548 -0.08795631732192 0.627140624447965 0.884473755683602
1552619_a_at -0.477097792941406 -0.803355750599058 0.647827904584163 0.891785828193342
1552621_at -1.10302107472593 -0.342910805074846 0.306488932709794 0.727301030150504
1552622_s_at -1.72149401886825 -0.442472881809963 0.128836363478302 0.565595778318088
1552625_a_at 1.84013964116068 0.396536696634447 0.108322774752044 0.535809610096853
1552627_a_at 2.0038833336338 0.705770667703333 0.0851303599151031 0.498283316976425
1552628_a_at -1.57496012546391 -0.407148818049683 0.159267517836855 0.601589103438657
1552629_a_at -1.43893517659071 -0.139437737398725 0.193341596944737 0.635525068556603
1552633_at -0.858557162681858 -0.108174887404548 0.419009952496557 0.788766055493427
1552634_a_at -0.734691255078869 -0.115137302901225 0.486405054946652 0.822635361903086
1552639_at 0.75440919476759 0.140258597624961 0.475212139456589 0.816018092484332
1552641_s_at -0.823690394922604 -0.401890522672562 0.437275443590422 0.797901555864165
1552643_at 0.584729743804482 0.116327576037331 0.5770819281806 0.86408531371228
1552644_a_at -1.10009893902834 -0.185285597147591 0.307675997740211 0.728266458428952
1552648_a_at -1.73040359431143 -0.66053150639621 0.127175239758108 0.562201327237327
1552649_a_at -0.59343835951128 -0.164440080314983 0.571556363255086 0.861292270963246
1552651_a_at -1.02554360521094 -0.192668386611722 0.33923447982315 0.747018958004469
1552656_s_at -0.742812379202681 -0.252372453513516 0.481774016226782 0.819552473684137
1552658_a_at 0.273909778183438 0.189145849594231 0.792060436801475 0.9406882816237
1552660_a_at -0.507650605468657 -0.161810603775852 0.627298600186011 0.884473755683602
1552661_at -1.01907760641467 -0.0885425782842306 0.342087988527633 0.748661641371574
1552662_a_at 0.14793362479891 0.0235635866304729 0.886566234450188 0.968322468296418
1552663_a_at -0.809449936908988 -0.16267176879373 0.444895236112152 0.801044100231637
1552664_at -0.396042626714104 -0.0970990413929442 0.70386785938843 0.911788377933647
1552665_at -0.541914726467524 -0.0980880162811744 0.604690109597914 0.875926494039526
1552667_a_at 1.31113767696887 0.220049563192344 0.231181156283436 0.671830714021929
1552670_a_at -0.57047372087305 -0.10292542674241 0.586193534307702 0.86822524668074
1552671_a_at 2.27761003151604 0.517921513878588 0.0568361751183845 0.436559380529566
1552678_a_at -1.94674054708241 -0.47104442101533 0.0926110988944094 0.511807056549432
1552680_a_at -1.49846987252938 -0.730230700640175 0.177685267838971 0.621079611317325
1552682_a_at -1.0470556706371 -0.448026632874571 0.329875662267673 0.74182078677778
1552684_a_at 0.345525779753881 0.0718897646372043 0.739850070474468 0.923831444319362
1552696_at 0.374957376282677 0.069354618217961 0.718794373471285 0.917388023555904
1552701_a_at 1.56357758774306 0.452072875117272 0.161892175804425 0.605478190018212
1552703_s_at 0.398279350584861 0.145177753737226 0.702292489196385 0.91122825896871
1552711_a_at 0.131783407026038 0.0329194369941614 0.898863448503998 0.972178945328683
1552717_s_at 0.81343503880744 0.221757838936596 0.442753570714063 0.799769585017262
1552721_a_at 0.162539625971038 0.0433623268383538 0.87547351634942 0.965340003127009
1552725_s_at -0.409676310319224 -0.0592716222023815 0.694289865717767 0.907433485383077
1552727_s_at 0.134883951220116 0.0142728696985852 0.896500183065704 0.971675718245394
1552729_at -0.53743787330781 -0.0866735025717364 0.607618559327457 0.877129016421874
1552733_at 1.07985880051255 0.31168456724605 0.316000671228236 0.733463320036645
1552737_s_at -4.04173658150276 -0.448588424796913 0.0049220289855288 0.179006363191593
1552738_a_at 1.44623693524059 0.300599406240103 0.1913566144596 0.632754606137106
1552739_s_at 1.41036142205622 0.775361154551142 0.201288143869437 0.645489829252002
1552767_a_at 2.83947726940025 0.383381487768234 0.0250633757043819 0.335336147801186
1552769_at -1.15428929558041 -0.129946772254657 0.286262788772939 0.713624773113517
1552771_a_at -0.354234852111812 -0.0594075240595195 0.733593527064999 0.921833507335612
1552772_at -0.243179685670906 -0.0199903679934863 0.814838523307026 0.946805633441932
1552775_at 0.443631565813594 0.0411527330442349 0.670697408907181 0.899799259593275
1552777_a_at 1.29151377261914 0.126886979727368 0.237532949736471 0.676408388923515
1552787_at -0.801798641846499 -0.107505769426534 0.449027446776633 0.802802809310956
1552789_at 1.19921888362592 0.184585370455292 0.269456652984079 0.702215334708739
1552790_a_at 2.28047403031026 0.475038628777718 0.0565967018808805 0.436069283735701
1552792_at 1.71409126362929 0.321023984727229 0.13023219882186 0.567699857640504
1552794_a_at 6.61622284117784 0.387652489490622 0.000299755784034172 0.057721186956761
1552801_at 1.33257566450581 0.196577151205765 0.224411482334992 0.666401323833869
1552803_a_at 0.0532716571613163 0.00869284857938712 0.95900389364922 0.988216389648856
1552804_a_at -0.605839975971087 -0.102374577345895 0.563741148698549 0.858936736587593
1552806_a_at 2.81280185891304 0.324476840226159 0.0260409454770248 0.340801880378467
1552812_a_at -0.320924419940431 -0.0971832327196456 0.757636538798665 0.930836092251519
1552822_at 4.07574610395885 1.00300566974416 0.00471491277622134 0.176962864857824
1552828_at -1.22573747804379 -0.218485410377305 0.25993137304958 0.695871414393027
1552830_at 0.0521730702234445 0.00541631721756808 0.959848444500434 0.988415212495918
1552833_at -0.774545134891315 -0.120070178768791 0.463962136009173 0.811114521061301
1552836_at -1.11023799842667 -0.180873964022299 0.303573113780312 0.725372259583939
1552841_s_at 0.893265106553685 0.131526065921602 0.40138047844333 0.778206540821556
1552842_at 0.298283114488548 0.0280947954378741 0.774146530483117 0.936191997556934
1552846_s_at -0.728462499948058 -0.0998766986206832 0.489976911899893 0.824814102480641
1552862_at -0.510814373556812 -0.0836097546006282 0.625192424797782 0.884121619531216
1552875_a_at 0.532332045756139 0.0596811367370229 0.610967890576152 0.878491193058159
1552892_at 0.389327185447891 0.053203006088844 0.708607030878522 0.913666582969935
1552895_a_at -0.550969718269957 -0.0659656359722183 0.598790784844746 0.872682598792199
1552902_a_at 1.79592323348994 0.155381720218791 0.115571892558355 0.545875657273117
1552903_at 0.187607295276069 0.0257224894222365 0.856506774513569 0.958318950414568
1552910_at -0.0264785086819871 -0.00210106196636861 0.979614723360284 0.993846574484899
1552911_at 0.162093498455164 0.0226417499477671 0.875811903571021 0.965434076927895
1552914_a_at -0.797240941070791 -0.288016512657647 0.451501563652415 0.804112894645537
1552921_a_at -1.20764427978074 -0.64404449733669 0.266398931591717 0.70004261233628
1552923_a_at 0.530199870590975 0.0658640768281686 0.612369526680737 0.878707508089731
1552925_at 0.891622582430128 0.267661334536641 0.402202335080229 0.778958575906146
1552927_at -1.53009915043957 -0.199618777823042 0.16984463938931 0.614918475809247
1552928_s_at -0.931275204080167 -0.150373098829773 0.382706766776184 0.770038388739996
1552931_a_at 3.18134857088503 0.465499410027738 0.0154616028462352 0.286039652655352
1552932_at 0.833939464290824 0.0717741966412579 0.43184863114682 0.795319207886653
1552935_at 0.203532534761762 0.0291354086910962 0.8445091264326 0.955427360434047
1552937_s_at 1.45153500817171 0.264155857787022 0.189927834194337 0.632055551135591
1552939_at -0.81090700166344 -0.174351964076537 0.444111344366159 0.800658652202818
1552946_at -0.458399381757492 -0.0816511571278413 0.660557533146539 0.896086702343944
1552954_at -1.31501524089847 -0.326729102176947 0.229943682476036 0.670731715610048
1552964_at -0.146963228555955 -0.0140010930820589 0.887304211904905 0.968788668124886
1552970_s_at -0.400298731987845 -0.0569706160340924 0.700871544030129 0.910689261684946
1552973_at 1.09738372458506 0.117639878283475 0.308782342513353 0.728653742888758
1552976_at 0.744385968900049 0.0799385280877054 0.48088009210806 0.81914514755986
1552977_a_at -0.0465063448328863 -0.0204925012979924 0.964205655080259 0.989164805110326
1552978_a_at 8.35375285910755 0.882328058718436 6.90752827718534e-05 0.0352445155854993
1552991_at 3.29603118473854 0.249227197063999 0.0131925547633744 0.269839625744345
1552995_at 0.50827523028162 0.0627642021236161 0.626882480451953 0.884473755683602
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