Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000233
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue Maternal uterine
Cell Line Prenatal chorion villus cells
Platform GPL570
Accession GSE6283
GEO Title Specific transcriptional changes in human fetus with autosomal trisomies
PMID 18253026
Article Title Specific transcriptional changes in human fetuses with autosomal trisomies
Author Altug-Teber O, Bonin M, Walter M, Mau-Holzmann UA, Dufke A, Stappert H, Tekesin I, HeilbroNoner H, Nieselt K, Riess O
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6283
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/18253026
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE6nnn/GSE6283/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1007_s_at 3.39837275047856 0.589129818417197 0.0114678686681511 0.276871460523902
1053_at -1.47292651460586 -0.790627743322116 0.184256344806485 0.590043831510012
117_at -1.32962379058427 -0.19586992429875 0.225333227913393 0.620852962952912
1294_at 2.77942372521581 0.758614938226637 0.0273209000093476 0.351666433717725
1320_at 2.17745488947019 0.268479744524412 0.0658878245396562 0.440639955150588
1405_i_at 1.06135419589358 0.250051531645325 0.32376914354955 0.687361237269787
1431_at 0.323092988472689 0.0341184838678581 0.756062155754154 0.911722876840963
1552256_a_at 1.85797097318145 0.656272357466041 0.105525326683499 0.502493643151575
1552257_a_at 0.102614412015179 0.0279903052041641 0.92114677041234 0.974689363437935
1552258_at -1.71572955142812 -0.253070456088353 0.129922058951931 0.528868774857099
1552263_at 0.462626916454124 0.145085506310951 0.657668717238832 0.866420706948596
1552264_a_at -0.641565740406764 -0.191157977802227 0.541584757302392 0.809176700749569
1552271_at -1.08897338998217 -0.083924025878571 0.312229672948485 0.681811113826527
1552274_at 0.386146191927924 0.160777533003127 0.710856754430386 0.891728137003613
1552275_s_at 0.0301127694364311 0.0128213788179714 0.976817686370008 0.993777337705642
1552277_a_at -0.362694485238514 -0.154510191146279 0.727536887708667 0.899728143881451
1552278_a_at 1.31342462734772 0.154546269756855 0.230450607130489 0.625639717469191
1552279_a_at 2.14957415418558 0.197452979530518 0.0686567853801007 0.444356999665567
1552283_s_at 1.16597745325052 0.125488873293172 0.281809036249316 0.664399718858905
1552286_at -1.41705593266809 -0.258609326826847 0.199400593589756 0.6021551905733
1552287_s_at -0.40561925814152 -0.0749423693015867 0.697133891472625 0.885747266449226
1552291_at -1.07265225050125 -0.228694889318779 0.31900811018384 0.684621964147887
1552295_a_at 1.69069410036137 0.739462801818494 0.134738677966725 0.535217255515772
1552299_at -1.19673802119447 -0.137064655591146 0.270362603068031 0.655782902356406
1552301_a_at 0.616576851735241 0.0771266773176782 0.557026280791769 0.818636920413234
1552302_at 7.23077481403133 0.849063731039264 0.000172780318231931 0.0726384218520605
1552303_a_at 3.44151991311832 0.626111323911467 0.0108148833910219 0.273436301736336
1552306_at -0.872600539056449 -0.44840561514377 0.411810305894367 0.737428379109765
1552307_a_at -0.0532570667384075 -0.0201211030231452 0.959015109830706 0.987856275961005
1552309_a_at 4.97491266076285 1.30639233256714 0.00161021057319696 0.159305833013464
1552310_at -0.990191743707376 -0.228141479642514 0.355065345505441 0.705645438704346
1552312_a_at 1.60103862702534 0.293904352832584 0.153401987622746 0.557111877027091
1552314_a_at -3.7542925250163 -0.394814473795582 0.00712795539992581 0.238735535466164
1552327_at -0.213399547092221 -0.0495344382592933 0.837097503857794 0.944047486459942
1552329_at -1.92884891722081 -0.460973296878026 0.0950833034401872 0.484585018165317
1552330_at 2.41363694057325 0.461671905995793 0.0465248303764059 0.40633909937211
1552332_at -0.937824437860973 -0.16662132384861 0.379555985710813 0.718784641502148
1552334_at 0.475381890669016 0.0774662328696412 0.648990906826778 0.861685199426986
1552335_at -0.414576082783724 -0.0494319213552572 0.690862116908538 0.882216045775038
1552344_s_at -0.0691270901176827 -0.0212533618609401 0.946821719975678 0.983188085094915
1552347_at 5.64574183705639 0.894873516644139 0.000777919282194526 0.121571424693007
1552354_at -5.04663897767521 -0.453074616101744 0.00148539644691803 0.154810058700549
1552360_a_at 2.50099347889976 0.263406513168086 0.0409326739309082 0.38927410861018
1552364_s_at 0.0141725050687257 0.00265662972112413 0.989087830910319 0.99693073418963
1552365_at 3.41699522432988 1.83473607793527 0.0111809732438752 0.275857488639769
1552367_a_at 3.62132584377971 1.21265478733719 0.00849520681055335 0.251009631015295
1552370_at -0.191184860272197 -0.12937618533527 0.853807860289652 0.949827896148667
1552377_s_at 1.90011250118438 0.411415828758026 0.0991896085143193 0.491466421718745
1552378_s_at 1.44614112439287 0.367626212314823 0.191382541495996 0.595827830663843
1552398_a_at -0.567560997236519 -0.0730948881063762 0.58806521210605 0.832048742513488
1552399_a_at -0.258247635651872 -0.0373833129780845 0.803644107481165 0.931185012258367
1552411_at -0.585348727967 -0.0716884085245457 0.576688168579811 0.826215595620686
1552417_a_at -0.816540909012643 -0.312374805718526 0.44108943792023 0.75451518887153
1552422_at 0.973345641681144 0.186729285667333 0.362807773148963 0.710719136229361
1552423_at -2.44585508418752 -0.478306612104278 0.0443761937389673 0.399781044617697
1552425_a_at 0.481784453180817 0.0772057282101763 0.64465676068013 0.85986126830011
1552432_at 1.2034677764496 0.172234121252612 0.267910987096377 0.654467006901121
1552457_a_at 1.89812306327217 0.542789049496217 0.0994802054821087 0.491924391686791
1552459_a_at 1.75468680341811 0.1785443700531 0.122750643347358 0.521118657323443
1552470_a_at -1.12638248075715 -0.18698038828193 0.297132105638217 0.674737168658058
1552473_at -0.279965651496758 -0.0401474971065072 0.787596402079455 0.925153030851828
1552474_a_at 1.66781263879408 0.54566758677323 0.139287978461455 0.541250627191341
1552476_s_at 2.41459603081006 0.800182036643895 0.0464593512953558 0.40633909937211
1552478_a_at -0.597858358741471 -0.070068390134375 0.568763739148528 0.823071991937767
1552481_s_at 0.892127666091089 0.320137664945409 0.401949478795455 0.731513760863017
1552482_at 3.68455893262019 0.308575434868246 0.00781250441278692 0.243528533565724
1552485_at 0.734890016018958 0.198846633085902 0.486291360838671 0.780013888458563
1552486_s_at 2.82617664367862 0.764028332720653 0.0255458846418492 0.345666960371821
1552487_a_at 0.840014331691981 0.52456256142919 0.428654686104511 0.748345525899291
1552489_s_at -1.11082102583433 -0.233145052782477 0.303338544270119 0.677432100256799
1552494_at -1.22845975017075 -0.161593085361999 0.258969871189101 0.648431698817036
1552496_a_at -1.10172676959605 -0.132519869564035 0.307014261724064 0.679607389078706
1552501_a_at -1.03265342028293 -0.11509945680521 0.33611847746371 0.695200671470787
1552502_s_at 5.8306275881225 0.752384875003608 0.00064314152175122 0.110266704908554
1552507_at -0.11061123434143 -0.0556536519872042 0.915029203006149 0.972558204760195
1552510_at -0.0835155821084204 -0.0106558961318726 0.935779734982833 0.979544436336394
1552540_s_at -0.640200665653065 -0.108475081264563 0.542421487412027 0.809433424425554
1552546_a_at -1.01748213054338 -0.634063881897532 0.342794974110267 0.698245672745112
1552549_a_at -1.13623168800387 -0.143367745175841 0.293257884853426 0.673064466054002
1552559_a_at 0.203456774387027 0.0399680794805795 0.844566100445056 0.946358800290431
1552569_a_at -1.02861786078774 -0.105645022526977 0.337884355486888 0.696215939166605
1552573_s_at 0.906596991353027 0.112907845515345 0.394755440265536 0.7279588675282
1552575_a_at -0.244142877817757 -0.0437160693675018 0.814121518322079 0.934225990854773
1552576_at -1.01781447674764 -0.136422031517326 0.34264761093188 0.698181901657034
1552580_at -0.229526249525765 -0.0242580344582946 0.825022354496549 0.938630074242022
1552583_s_at 1.5203284438337 0.202568841285728 0.172232275636375 0.576213971356039
1552586_at 0.100522691142237 0.01156438875846 0.922747899918047 0.974847339479706
1552598_at 1.87748855814511 0.184982285328491 0.10254357011967 0.498035179547032
1552608_at -2.21566387304068 -0.187402765526184 0.0622744929360335 0.435236064528111
1552610_a_at -1.38331937558557 -0.219745793073777 0.209075837648554 0.609118595486702
1552611_a_at -0.449087617463214 -0.0980110401305483 0.666942447950256 0.871198358387375
1552612_at 1.69873273927203 0.452063842824477 0.133173990668445 0.533844270589003
1552613_s_at 2.48452383609878 0.329786365667889 0.0419314117513903 0.391453215059172
1552615_at -0.951123749008808 -0.162408745320317 0.373218053176733 0.716018559688321
1552619_a_at -0.665462567318331 -1.16338270716011 0.527065775326676 0.801699810477466
1552620_at 0.393015446065554 0.0556202871032632 0.706002448586302 0.889498586310043
1552621_at 0.827077990079474 0.228306261506563 0.435476427411419 0.751963715570618
1552622_s_at 1.39548984422914 0.375199666879479 0.205538382853925 0.607178726204639
1552625_a_at -2.10867108197358 -0.355954285518481 0.0729314000319218 0.451886727767564
1552627_a_at -0.522808799518687 -0.145390094074807 0.617241681463367 0.847079802224323
1552628_a_at 1.60036780933548 0.399246155068507 0.153550320438143 0.557232059107558
1552631_a_at -0.747105203227897 -0.108316519442868 0.479337963251294 0.775586775571215
1552633_at -1.44593693189262 -0.183360120066249 0.191437807858482 0.595850995256321
1552634_a_at -1.97796829671056 -0.418497727803061 0.0884462958207673 0.477672973433915
1552639_at 0.00141283226948903 0.000300391147324497 0.998912143723186 0.999648867123244
1552641_s_at 0.00221017500997765 0.00108973930390377 0.99829820461607 0.999432842355505
1552643_at 1.78353519106087 0.296775198381449 0.117685122677798 0.514320471324954
1552644_a_at -1.22850336091491 -0.17379955150186 0.258954492526676 0.648431698817036
1552648_a_at -1.02402934620577 -0.494341192874566 0.339901055518524 0.696901803723443
1552649_a_at -0.876277130472374 -0.259282204693947 0.409940344786812 0.736985833510274
1552651_a_at -0.50213190415898 -0.117369163383452 0.63098141922289 0.853751209452728
1552656_s_at 0.845892163924492 0.312636526223625 0.425580399168968 0.746827432200085
1552657_a_at 2.401529637754 0.204668682530645 0.0473596016450437 0.408336369598852
1552658_a_at -0.126523611532059 -0.083324944143838 0.902875021546696 0.969393545734581
1552660_a_at 0.769349250842478 0.264947244652728 0.466847596035811 0.76817318940811
1552661_at -0.846008978343491 -0.0918161309317789 0.425519461815455 0.746827432200085
1552663_a_at -0.919890777656061 -0.166590344703126 0.388230377626506 0.72460824958779
1552664_at 2.32168521607593 0.399980441802836 0.0532620927135721 0.41806760067152
1552665_at -0.314923858416333 -0.0642434176342954 0.761999365082165 0.914493233115804
1552667_a_at 0.580304382391495 0.0865687989784973 0.579901590060395 0.828047635401438
1552671_a_at 3.81687736496169 1.11143856967351 0.00656887051179011 0.235103759499605
1552674_at -0.395302600108568 -0.0416677071529614 0.704389419142983 0.888573292022465
1552677_a_at 3.54318529942446 0.450464405917677 0.00942949056732024 0.258256438747489
1552678_a_at -0.72009659638811 -0.159152203341129 0.494801457686459 0.783900443949744
1552680_a_at -1.08595596102351 -0.582544752319474 0.313474042712396 0.682167257045062
1552682_a_at -0.211555704680243 -0.111735962634981 0.838481187487828 0.944341815035786
1552684_a_at 0.279249180719544 0.0836216255514346 0.788124099811216 0.925295239033669
1552685_a_at -1.8635482326436 -0.219092702532396 0.104664797828837 0.500872234404877
1552687_a_at -0.579804110068111 -0.0473617361422169 0.580220841457279 0.828047635401438
1552689_at -4.30336255377334 -0.530187831215418 0.0035519097788627 0.191179976269991
1552696_at 0.208870409850846 0.0386708197249179 0.840497421553181 0.945364855333491
1552701_a_at 0.295299007642608 0.0822734145691975 0.776332136106739 0.919939855002209
1552703_s_at -0.60008214118298 -0.177185364594111 0.567361746724239 0.822325586357732
1552711_a_at -0.69668712595459 -0.13961709888278 0.508465997069087 0.791726860993797
1552713_a_at -1.58003250774463 -0.24785348026093 0.158110615786686 0.562816904532817
1552716_at 1.85348212359617 0.274586584376914 0.106222896831783 0.502529418138585
1552717_s_at -0.835738513388456 -0.200912580561586 0.430900998084059 0.749868246363095
1552721_a_at 1.72173278036249 0.504908395891176 0.128791580713493 0.527879265804523
1552725_s_at -0.646631982376498 -0.0996666823337069 0.538486294094271 0.807374629175168
1552727_s_at -0.408955136939444 -0.0337939277633015 0.694795029928182 0.884561408393274
1552733_at 1.18192771875952 0.267254180238335 0.275824253027643 0.659679953565611
1552737_s_at -0.173665528926365 -0.0193651555280465 0.867043757295086 0.95531198146712
1552738_a_at 0.721307328515551 0.152815325156271 0.494101316006504 0.783900443949744
1552739_s_at 1.81818890883358 0.821037466327926 0.111864981934579 0.51015109344869
1552749_a_at -0.184672287312019 -0.0365672453935053 0.858722484255266 0.951325712231187
1552755_at -2.71598821887055 -0.210771619896904 0.029938689602615 0.361046351795661
1552768_at -1.26055089433322 -0.185095132376778 0.247861425625215 0.640197495738877
1552770_s_at -0.0916771182503786 -0.00926881767952104 0.929522990111723 0.977266085322297
1552771_a_at -1.89437890293892 -0.344778153427843 0.100029364866494 0.493453364647509
1552773_at 1.32675792979223 0.158390347087257 0.226231278837539 0.621921542555729
1552777_a_at 0.1758599279001 0.0194414917437489 0.865383277837753 0.954483814058152
1552787_at -0.181495368635057 -0.0339203367122294 0.861122357541671 0.952322996032274
1552789_at -1.17069493003957 -0.230596653138643 0.280027816459509 0.662970423657712
1552790_a_at -1.07657886726579 -0.235075631918393 0.317366617644953 0.684056910060665
1552791_a_at -0.280071626411851 -0.0286613634059889 0.787518359187741 0.92514095319138
1552794_a_at 3.8862093497252 0.477575960213686 0.00600467767403247 0.226469238352391
1552798_a_at -1.08211407935066 -0.375015312589651 0.315064193327074 0.682489283639393
1552803_a_at -1.09702454487544 -0.170281804121986 0.308928935343392 0.680717502796844
1552804_a_at 0.93722527662584 0.163943556387662 0.379843422889584 0.719103432578566
1552806_a_at 0.692203477703931 0.0921961155181736 0.511110687138381 0.793292128858105
1552812_a_at 0.13724674887358 0.0389055331675836 0.894699990215448 0.965792138394332
1552822_at -0.251193241229969 -0.051639484902382 0.808879054370158 0.932818102203465
1552825_at 2.54115691654747 0.210446968952458 0.038598745210724 0.383364411200909
1552828_at -1.46499095345539 -0.21801958673283 0.186342180394484 0.591799226764804
1552829_at -0.754709947828835 -0.105396238398901 0.475042765504828 0.773116847523203
1552830_at 0.574343035207227 0.0539989105799328 0.583712413561489 0.830018807723273
1552833_at -0.670212327916035 -0.0632672738698936 0.524209164625926 0.799895555160747
1552842_at 0.84019733863535 0.0969944641138172 0.428558729498529 0.748271927085289
1552846_s_at 0.638121532618807 0.098433780889275 0.543697420885883 0.810284904425644
1552853_at 0.416010704792259 0.0662752823109285 0.689859959190378 0.881732023995664
1552862_at 1.63135797934649 0.285093372655937 0.146835330095203 0.548920093422441
1552867_at 1.10236929286591 0.18615853519824 0.306753384908791 0.679289636754173
1552872_at -0.833579827308781 -0.116764883760919 0.432038244127049 0.750405939554799
1552890_a_at -1.05087124567891 -0.249602990467769 0.328237248078224 0.690508665332215
1552903_at -1.19152015056001 -0.125413611551155 0.272276385407689 0.657330758955892
1552911_at -0.280389337207744 -0.0425854103010002 0.787284403763248 0.925025298156594
1552914_a_at 0.921479074485533 0.367241289336409 0.387456193903956 0.724088532609906
1552921_a_at -1.28653849341655 -0.715864129643307 0.239167133592713 0.63244934597403
1552925_at 0.75141232568434 0.232781633906726 0.476902093207904 0.774629026062401
1552929_at -1.4402115902278 -0.168908832440906 0.192993274545809 0.59762693975367
1552931_a_at -7.88911937143757 -0.74151023875046 9.96344254970527e-05 0.0672607065934483
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