Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000189
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Mus musculus
Tissue Brain
Cell Line Hippocampus
Platform GPL13730
Accession GSE49635
GEO Title Analysis of the Cerebral Cortex and Hippocampus Transcriptome Reveals Unique Molecular Changes in the Ts1Cje Mouse Model of Down Syndrome
PMID 25975229
Article Title The fetal brain transcriptome and neonatal behavioral pheNtype in the Ts1Cje mouse model of Down syndrome
Author Guedj F, Pennings JA, Wick HC, Slonim DK, Bianchi DW
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE49635
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/25975229
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE49nnn/GSE49635/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

Gene Symbol Gene Title logFC P-value P-adj
13411 3.12023167 4.63e-14 9.82e-10
54720 0.38923168 2.23e-06 2.23e-02
13508 0.47762091 4.61e-06 2.23e-02
217951 -0.40605364 4.71e-06 2.23e-02
13548 0.34263605 6.03e-06 2.23e-02
104015 0.41199189 7.26e-06 2.23e-02
13185 0.47019018 7.35e-06 2.23e-02
70028 0.39307074 9.50e-06 2.29e-02
20655 0.73864341 1.01e-05 2.29e-02
93871 0.41186195 1.08e-05 2.29e-02
207932 0.36804612 2.15e-05 3.95e-02
14450 0.30210152 2.28e-05 3.95e-02
320910 -0.8114719 2.42e-05 3.95e-02
224582 0.51255332 2.69e-05 4.07e-02
15975 0.4603314 3.14e-05 4.20e-02
71446 0.44342723 3.17e-05 4.20e-02
20658 0.44856486 3.77e-05 4.71e-02
224432 0.35891462 4.23e-05 4.95e-02
16443 0.41526636 5.00e-05 4.95e-02
100503583 0.58248265 5.13e-05 4.95e-02
68001 0.35949084 5.21e-05 4.95e-02
23872 0.43556149 5.31e-05 4.95e-02
18546 0.27806695 5.36e-05 4.95e-02
66609 0.46854207 6.13e-05 5.42e-02
15980 0.35347991 8.49e-05 7.10e-02
121022 0.25843721 8.78e-05 7.10e-02
26559 0.38701651 9.03e-05 7.10e-02
60364 0.44314722 1.21e-04 9.16e-02
207781 0.44600405 1.54e-04 1.13e-01
28080 0.4025152 1.86e-04 1.28e-01
70458 0.38852684 1.87e-04 1.28e-01
22129 0.33467454 2.36e-04 1.57e-01
77975 0.34490198 2.53e-04 1.63e-01
53970 -0.34065201 3.60e-04 2.25e-01
68936 0.32925916 4.42e-04 2.66e-01
387609 -0.21684877 4.52e-04 2.66e-01
16522 0.35275592 5.44e-04 3.12e-01
56088 0.29106412 5.78e-04 3.23e-01
13070 -0.38000352 8.12e-04 4.38e-01
433229 0.36556062 8.42e-04 4.38e-01
330403 0.39573046 8.46e-04 4.38e-01
407788 -0.42762126 8.78e-04 4.43e-01
77125 0.35552803 9.39e-04 4.63e-01
223978 -0.23497758 1.00e-03 4.68e-01
22441 0.8280874 1.03e-03 4.68e-01
17304 -0.24251966 1.06e-03 4.68e-01
433319 0.75151477 1.07e-03 4.68e-01
258392 0.42581721 1.14e-03 4.68e-01
103140 -0.23525051 1.15e-03 4.68e-01
71833 -0.17310494 1.15e-03 4.68e-01
67242 -0.38978043 1.16e-03 4.68e-01
171195 0.42278968 1.17e-03 4.68e-01
258488 0.27573497 1.18e-03 4.68e-01
100302565 -0.93366705 1.19e-03 4.68e-01
243085 0.33230928 1.24e-03 4.71e-01
114565 0.22733452 1.24e-03 4.71e-01
243764 0.20155629 1.33e-03 4.94e-01
171248 0.37182126 1.35e-03 4.94e-01
381286 0.52410669 1.39e-03 4.97e-01
20389 -0.32249543 1.41e-03 4.97e-01
14451 -0.25946251 1.50e-03 5.16e-01
16155 0.3763485 1.52e-03 5.16e-01
217258 0.30655586 1.56e-03 5.16e-01
69574 0.23271432 1.56e-03 5.16e-01
100039139 0.27987337 1.62e-03 5.24e-01
242594 0.30500243 1.63e-03 5.24e-01
93961 0.33808812 1.67e-03 5.26e-01
56362 0.2859507 1.69e-03 5.26e-01
110948 0.25869292 1.89e-03 5.80e-01
15976 0.42957785 2.01e-03 6.10e-01
16623 0.45606162 2.07e-03 6.12e-01
238330 -0.24765074 2.09e-03 6.12e-01
12408 0.31045675 2.11e-03 6.12e-01
13731 -0.1986149 2.26e-03 6.44e-01
17858 0.43016445 2.27e-03 6.44e-01
20688 -0.37480734 2.36e-03 6.51e-01
723959 0.30295297 2.36e-03 6.51e-01
69902 -0.66232242 2.41e-03 6.55e-01
258479 0.31014618 2.53e-03 6.79e-01
13549 -0.19637512 2.72e-03 7.15e-01
71755 -0.32741689 2.76e-03 7.15e-01
791295 0.35171192 2.77e-03 7.15e-01
243862 0.25933 2.79e-03 7.15e-01
258475 0.25292016 2.93e-03 7.40e-01
258550 0.435979 2.99e-03 7.44e-01
27210 -0.54057318 3.11e-03 7.44e-01
15561 0.22184647 3.11e-03 7.44e-01
257885 0.38740424 3.19e-03 7.44e-01
27212 -0.26927827 3.24e-03 7.44e-01
16639 0.21592951 3.25e-03 7.44e-01
18379 0.2424874 3.25e-03 7.44e-01
73677 0.30423998 3.28e-03 7.44e-01
229571 0.36128902 3.34e-03 7.44e-01
494546 0.28878584 3.36e-03 7.44e-01
100503486 0.28417419 3.45e-03 7.44e-01
55948 0.84327472 3.47e-03 7.44e-01
68527 0.37665457 3.48e-03 7.44e-01
239036 -0.2853399 3.53e-03 7.44e-01
383770 0.67512289 3.53e-03 7.44e-01
22228 -0.28739353 3.54e-03 7.44e-01
15220 -0.20006605 3.55e-03 7.44e-01
387139 0.40387408 3.57e-03 7.44e-01
258899 0.27615719 3.71e-03 7.64e-01
258478 0.30583741 3.75e-03 7.66e-01
213450 0.38518229 4.04e-03 8.16e-01
12931 -0.25249845 4.14e-03 8.28e-01
669780 0.58629473 4.33e-03 8.59e-01
276919 -0.31643199 4.42e-03 8.68e-01
246738 0.32845907 4.48e-03 8.70e-01
100038488 0.37088135 4.51e-03 8.70e-01
211770 0.24064164 4.55e-03 8.71e-01
77117 0.5742891 4.67e-03 8.81e-01
258815 0.30687641 4.69e-03 8.81e-01
27370 -0.40522059 4.74e-03 8.83e-01
259047 0.36629814 4.89e-03 8.91e-01
449631 -0.26384333 4.91e-03 8.91e-01
69944 -0.29315506 4.91e-03 8.91e-01
11606 -0.25821511 5.01e-03 9.02e-01
20208 0.30735505 5.10e-03 9.10e-01
723951 0.43579409 5.20e-03 9.16e-01
75180 -0.24352615 5.24e-03 9.16e-01
623166 -0.31147306 5.26e-03 9.16e-01
27209 -0.44322708 5.36e-03 9.25e-01
66153 -0.24154073 5.44e-03 9.31e-01
72017 0.2099138 5.63e-03 9.52e-01
319176 0.15813015 5.65e-03 9.52e-01
66943 -0.18538863 5.74e-03 9.58e-01
97895 0.21432763 5.78e-03 9.58e-01
18596 -0.18247104 5.90e-03 9.71e-01
18780 0.25601633 6.00e-03 9.79e-01
387164 0.28256881 6.14e-03 9.90e-01
259014 0.29526119 6.19e-03 9.90e-01
668035 0.37729686 6.21e-03 9.90e-01
114604 0.14199942 6.31e-03 9.98e-01
546055 0.32956145 6.37e-03 9.98e-01
66755 0.29325505 6.40e-03 9.98e-01
67261 -0.40427342 6.71e-03 1.00
627821 0.1616003 6.86e-03 1.00
66140 -0.1840059 6.87e-03 1.00
671652 0.35349574 6.94e-03 1.00
100217426 -0.40077398 7.07e-03 1.00
100503763 0.32632114 7.14e-03 1.00
100503047 0.22845187 7.24e-03 1.00
54159 -0.30661508 7.26e-03 1.00
21923 -0.31802398 7.32e-03 1.00
100503812 -0.25532068 7.41e-03 1.00
215919 0.28294265 7.49e-03 1.00
224291 -0.2562632 7.49e-03 1.00
12411 -0.2376423 7.78e-03 1.00
259165 0.30486173 7.79e-03 1.00
230577 -0.24205358 7.80e-03 1.00
18710 -0.24928857 8.07e-03 1.00
66747 0.28069108 8.22e-03 1.00
11731 0.3527869 8.30e-03 1.00
93837 0.2586704 8.36e-03 1.00
319172 -0.26850035 8.38e-03 1.00
258236 0.66680375 8.47e-03 1.00
225872 0.54313306 8.52e-03 1.00
72301 -0.20384991 8.68e-03 1.00
18676 -0.15940815 8.69e-03 1.00
280621 0.28523952 8.75e-03 1.00
68133 0.26353416 8.80e-03 1.00
17962 0.20291769 8.87e-03 1.00
63954 0.26842418 8.89e-03 1.00
329918 0.36422315 8.91e-03 1.00
18129 -0.20219709 8.97e-03 1.00
228598 -0.14071206 9.02e-03 1.00
94215 0.29828824 9.08e-03 1.00
545850 -0.64106058 9.30e-03 1.00
67367 0.33215321 9.35e-03 1.00
53881 0.33034537 9.42e-03 1.00
100041598 0.32036984 9.54e-03 1.00
57274 -0.20367138 9.66e-03 1.00
171255 0.28433836 9.74e-03 1.00
110460 -0.17925624 9.75e-03 1.00
235472 -0.20428041 9.79e-03 1.00
74686 0.1931562 9.85e-03 1.00
27050 -0.16039977 1.00e-02 1.00
113845 0.41936084 1.01e-02 1.00
258552 0.19717724 1.01e-02 1.00
230991 -0.18698282 1.02e-02 1.00
623924 0.175475 1.02e-02 1.00
17835 0.29438842 1.03e-02 1.00
245525 0.20489879 1.04e-02 1.00
84543 0.25883746 1.05e-02 1.00
100038431 0.26647036 1.06e-02 1.00
319190 -0.17167099 1.06e-02 1.00
14619 -0.25587207 1.09e-02 1.00
20377 -0.25210171 1.10e-02 1.00
17773 0.28279659 1.11e-02 1.00
114875 0.27960911 1.13e-02 1.00
258325 0.28080951 1.15e-02 1.00
629203 0.30547817 1.15e-02 1.00
27055 -0.16768266 1.15e-02 1.00
14166 -0.13936205 1.16e-02 1.00
54128 -0.21039562 1.18e-02 1.00
69077 -0.30475995 1.19e-02 1.00
66601 0.18075313 1.19e-02 1.00
207854 0.37013243 1.20e-02 1.00
667597 0.27145754 1.22e-02 1.00
19201 0.2076696 1.24e-02 1.00
232415 0.3286813 1.24e-02 1.00
13067 0.19722728 1.25e-02 1.00
387175 0.23385777 1.27e-02 1.00
80509 0.26620223 1.28e-02 1.00
226413 -0.25802321 1.28e-02 1.00
214189 0.17733307 1.29e-02 1.00
16819 0.20255779 1.29e-02 1.00
12443 -0.15666535 1.29e-02 1.00
73250 0.25692885 1.30e-02 1.00
16939 -0.20152293 1.30e-02 1.00
338467 0.46361464 1.30e-02 1.00
105418 0.24565272 1.31e-02 1.00
21380 -0.32307548 1.31e-02 1.00
229615 -0.20487747 1.32e-02 1.00
69666 -0.16340809 1.32e-02 1.00
234564 0.28260999 1.34e-02 1.00
232146 -0.20778355 1.34e-02 1.00
193453 0.18216789 1.37e-02 1.00
74762 -0.15237005 1.38e-02 1.00
171229 0.3105812 1.38e-02 1.00
108052 -0.16760375 1.41e-02 1.00
68618 -0.24412136 1.41e-02 1.00
226075 -0.19686184 1.42e-02 1.00
12444 -0.14457551 1.42e-02 1.00
113865 0.17415316 1.44e-02 1.00
171166 0.20766809 1.44e-02 1.00
13113 0.2168645 1.45e-02 1.00
83436 -0.14576487 1.45e-02 1.00
675969 0.34451386 1.46e-02 1.00
69318 0.18989501 1.47e-02 1.00
216011 -0.14524374 1.47e-02 1.00
108116 -0.15114104 1.47e-02 1.00
106393 0.1371579 1.48e-02 1.00
27361 0.259015 1.50e-02 1.00
56176 0.18733106 1.51e-02 1.00
94111 0.17857885 1.51e-02 1.00
27208 -0.37420603 1.52e-02 1.00
101604 -0.14195933 1.52e-02 1.00
20928 -0.15399356 1.53e-02 1.00
13197 -0.19755255 1.53e-02 1.00
67315 0.22215242 1.53e-02 1.00
68566 -0.1915896 1.53e-02 1.00
630579 0.25773253 1.54e-02 1.00
14261 -0.12514846 1.57e-02 1.00
382239 0.18981231 1.58e-02 1.00
259001 0.22856571 1.58e-02 1.00
100040843 0.47831609 1.58e-02 1.00
66307 -0.17310507 1.58e-02 1.00
194227 0.2637537 1.59e-02 1.00
56463 -0.10820901 1.59e-02 1.00
75801 0.54893384 1.59e-02 1.00
12496 -0.18370744 1.61e-02 1.00
17022 -0.2342019 1.61e-02 1.00
18682 -0.21910644 1.61e-02 1.00
71398 0.35743856 1.61e-02 1.00
13525 0.24898111 1.62e-02 1.00
73344 0.16304532 1.62e-02 1.00
56429 0.36668702 1.63e-02 1.00
66578 0.28502916 1.63e-02 1.00
319880 -0.14784989 1.63e-02 1.00
171197 0.3498692 1.64e-02 1.00
11932 -0.11694291 1.64e-02 1.00
22631 -0.18250146 1.64e-02 1.00
11304 -0.29178815 1.65e-02 1.00
69865 0.18525547 1.65e-02 1.00
13586 0.31481217 1.66e-02 1.00
330440 0.22962433 1.66e-02 1.00
68262 -0.20834992 1.67e-02 1.00
100038586 0.4488473 1.67e-02 1.00
20311 0.27777027 1.68e-02 1.00
216144 0.235056 1.69e-02 1.00
216166 -0.17364039 1.70e-02 1.00
22171 0.34221603 1.71e-02 1.00
258374 0.28554308 1.72e-02 1.00
66686 -0.19313311 1.72e-02 1.00
15078 -0.53571365 1.73e-02 1.00
12759 -0.11830156 1.73e-02 1.00
258264 0.27374749 1.73e-02 1.00
258789 0.38407004 1.73e-02 1.00
58861 0.25051544 1.75e-02 1.00
80828 -0.37721364 1.75e-02 1.00
257931 0.23707245 1.75e-02 1.00
56699 -0.12049758 1.75e-02 1.00
243912 -0.2460699 1.75e-02 1.00
258198 0.34237148 1.76e-02 1.00
66980 0.16902702 1.76e-02 1.00
75610 0.2107242 1.77e-02 1.00
66211 -0.21845671 1.77e-02 1.00
381668 -0.14392673 1.77e-02 1.00
12927 -0.13981618 1.78e-02 1.00
113860 0.20389586 1.78e-02 1.00
110058 -0.16328071 1.79e-02 1.00
258766 0.17309315 1.79e-02 1.00
213054 -0.12147466 1.79e-02 1.00
216443 -0.13122216 1.79e-02 1.00
19885 -0.19443799 1.79e-02 1.00
14941 0.17566538 1.81e-02 1.00
67556 -0.12357494 1.81e-02 1.00
75942 0.24810632 1.82e-02 1.00
208613 -0.20256356 1.84e-02 1.00
71918 -0.20347476 1.85e-02 1.00
100503402 0.43915167 1.85e-02 1.00
16821 0.22959366 1.86e-02 1.00
22350 -0.17465578 1.86e-02 1.00
19044 -0.14966666 1.86e-02 1.00
75359 0.16272537 1.89e-02 1.00
258074 0.3035223 1.90e-02 1.00
71973 -0.3608542 1.91e-02 1.00
20911 -0.19902386 1.91e-02 1.00
433247 0.32506404 1.91e-02 1.00
235493 -0.21474636 1.92e-02 1.00
72560 0.29258354 1.92e-02 1.00
407785 0.1609154 1.93e-02 1.00
16848 -0.16205068 1.94e-02 1.00
382543 0.25616175 1.96e-02 1.00
16977 -0.22359713 1.97e-02 1.00
100038695 0.1742629 1.97e-02 1.00
100503428 -0.20840157 1.97e-02 1.00
74354 -0.13962624 1.98e-02 1.00
26425 -0.13535675 1.99e-02 1.00
14999 -0.67442419 1.99e-02 1.00
404336 -0.74288878 1.99e-02 1.00
17025 -0.50577708 1.99e-02 1.00
381270 -0.14861357 2.00e-02 1.00
100042464 -0.19426505 2.01e-02 1.00
66381 -0.14497902 2.01e-02 1.00
387213 0.17165332 2.02e-02 1.00
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14813 -0.12921587 2.02e-02 1.00
735279 0.18470846 2.03e-02 1.00
667952 0.32270949 2.04e-02 1.00
12577 -0.12153007 2.06e-02 1.00
117229 0.20636271 2.07e-02 1.00
21944 -0.68906777 2.08e-02 1.00
57269 -0.35028558 2.09e-02 1.00
723888 0.22484125 2.09e-02 1.00
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16011 -0.20109418 2.10e-02 1.00
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21927 -0.14347817 2.12e-02 1.00
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66983 -0.20886404 2.13e-02 1.00
12964 -0.27585608 2.14e-02 1.00
77042 0.19223186 2.14e-02 1.00
107585 -0.28220648 2.14e-02 1.00
277939 -0.12569151 2.16e-02 1.00
76877 -0.14003942 2.18e-02 1.00
224440 0.13678706 2.18e-02 1.00
67328 0.15949751 2.18e-02 1.00
100503720 0.2068853 2.19e-02 1.00
23793 0.1891219 2.20e-02 1.00
114672 -0.74253868 2.21e-02 1.00
107993 0.2455242 2.21e-02 1.00
53868 0.19646469 2.21e-02 1.00
76302 -0.29904413 2.21e-02 1.00
11647 -0.17824745 2.22e-02 1.00
353374 -0.27136523 2.22e-02 1.00
15547 -0.21406622 2.22e-02 1.00
64929 0.20521324 2.22e-02 1.00
236844 0.37961554 2.23e-02 1.00
15039 0.31013218 2.24e-02 1.00
55994 -0.12430033 2.24e-02 1.00
338368 0.23285543 2.24e-02 1.00
69291 -0.18785216 2.24e-02 1.00
76608 -0.17240729 2.25e-02 1.00
668597 0.63744201 2.26e-02 1.00
76386 0.20199807 2.27e-02 1.00
78004 0.22581725 2.27e-02 1.00
77619 0.30372466 2.29e-02 1.00
408065 0.16940619 2.31e-02 1.00
102693 0.11811189 2.32e-02 1.00
12827 0.13302209 2.32e-02 1.00
19309 0.18261288 2.32e-02 1.00
214704 -0.33801835 2.33e-02 1.00
14404 0.17190288 2.34e-02 1.00
360198 0.35526895 2.34e-02 1.00
258684 0.46773637 2.34e-02 1.00
243944 0.52225327 2.34e-02 1.00
18423 -0.18105928 2.34e-02 1.00
503491 0.37324868 2.34e-02 1.00
404322 0.2131193 2.34e-02 1.00
100038371 0.24191602 2.35e-02 1.00
76390 0.2757193 2.36e-02 1.00
16434 -0.32920952 2.36e-02 1.00
12810 -0.17413426 2.36e-02 1.00
16193 0.26016177 2.37e-02 1.00
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