Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000169
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Mus musculus
Tissue Brain
Cell Line Cerebral cortex
Platform GPL13730
Accession GSE99135
GEO Title Life Span Analysis of Brain Development, Gene Expression and Behavioral PheNtypes in the Ts1Cje, Ts65Dn and Dp16 Mouse Models of Down Syndrome
PMID 29716957
Article Title Lifespan analysis of brain development, gene expression and behavioral pheNtypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome
Author Aziz N, Guedj F, Olmos-SerraN LJ, Pennings JL, Siegel AE, Bianchi DW, Haydar TF
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi
Pub Link -
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE99nnn/GSE99135/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

Gene Symbol Gene Title logFC P-value P-adj
13411 3.22331919 7.34e-17 1.56e-12
320910 -0.66151087 2.89e-09 3.07e-05
20658 0.47590909 1.23e-08 8.67e-05
60364 0.48769506 1.81e-08 9.63e-05
15975 0.44269452 5.94e-08 2.52e-04
16443 0.39550032 7.29e-08 2.58e-04
67367 0.47117012 9.56e-08 2.90e-04
93871 0.52028529 1.64e-07 4.35e-04
104015 0.37619582 2.65e-07 6.26e-04
15976 0.39690981 4.21e-07 8.95e-04
77975 0.44933565 4.68e-07 9.03e-04
207781 0.40510615 5.74e-07 1.02e-03
20688 -0.36732615 6.41e-07 1.02e-03
338467 0.44358656 7.14e-07 1.02e-03
54720 0.37141701 7.18e-07 1.02e-03
70028 0.41869904 8.75e-07 1.12e-03
207932 0.38047753 8.94e-07 1.12e-03
22129 0.27956893 1.38e-06 1.63e-03
15980 0.37102315 1.49e-06 1.66e-03
13185 0.58310065 1.74e-06 1.85e-03
20655 0.53462115 1.96e-06 1.96e-03
237246 0.33237866 2.12e-06 1.96e-03
14450 0.44566957 2.18e-06 1.96e-03
75801 0.52139894 2.22e-06 1.96e-03
110948 0.29767638 2.52e-06 2.14e-03
56176 0.2999166 3.48e-06 2.84e-03
22017 0.40043201 4.18e-06 3.29e-03
66578 0.43162079 4.98e-06 3.78e-03
66609 0.43337198 5.39e-06 3.94e-03
56088 0.54012615 5.92e-06 4.18e-03
121022 0.39513767 6.10e-06 4.18e-03
53970 -0.31673179 7.23e-06 4.79e-03
224432 0.2873055 7.89e-06 5.08e-03
246738 0.35007485 9.42e-06 5.88e-03
114604 0.27515012 1.12e-05 6.77e-03
28080 0.43846829 1.15e-05 6.80e-03
320145 -0.35056727 1.25e-05 7.17e-03
57431 0.2575138 1.45e-05 7.91e-03
209195 0.31021165 1.45e-05 7.91e-03
12408 0.42318798 2.11e-05 1.12e-02
13548 0.25632083 3.06e-05 1.59e-02
71446 0.35050196 3.49e-05 1.76e-02
68001 0.43559956 3.62e-05 1.79e-02
211484 0.34925613 3.96e-05 1.91e-02
53881 0.47918216 4.49e-05 2.12e-02
26559 0.40427683 5.22e-05 2.41e-02
66079 0.22667722 5.78e-05 2.61e-02
72017 0.20316732 7.22e-05 3.19e-02
217951 -0.43512595 7.99e-05 3.46e-02
110749 0.46141857 8.86e-05 3.76e-02
74521 0.21910298 9.61e-05 4.00e-02
15185 0.23672137 1.11e-04 4.51e-02
320586 0.32131455 1.54e-04 6.11e-02
232560 0.18648045 1.55e-04 6.11e-02
114565 0.22676852 1.79e-04 6.89e-02
68936 0.18808952 1.99e-04 7.54e-02
320528 0.21890449 2.03e-04 7.54e-02
22228 -0.32486829 2.06e-04 7.54e-02
627967 -0.37324521 2.21e-04 7.94e-02
66736 0.17722431 2.34e-04 8.29e-02
93843 0.29973356 2.76e-04 9.60e-02
66273 0.18649936 2.99e-04 1.02e-01
23872 0.45010911 3.49e-04 1.18e-01
13508 0.36986525 3.79e-04 1.26e-01
15312 0.25449651 3.95e-04 1.29e-01
102566 0.20434148 4.43e-04 1.42e-01
213311 0.30992495 4.63e-04 1.47e-01
232223 0.23783642 5.41e-04 1.68e-01
13437 0.21074225 5.46e-04 1.68e-01
23917 0.20136281 7.34e-04 2.17e-01
215653 0.22691379 7.39e-04 2.17e-01
56175 0.19520048 7.43e-04 2.17e-01
106393 0.2201265 7.68e-04 2.17e-01
93961 0.24758861 7.70e-04 2.17e-01
19201 0.26136202 7.71e-04 2.17e-01
224440 0.17343505 7.78e-04 2.17e-01
54667 0.13564679 8.60e-04 2.34e-01
16155 0.2664933 8.61e-04 2.34e-01
11566 0.18743385 8.77e-04 2.34e-01
170460 0.1510175 8.81e-04 2.34e-01
246133 0.25632536 1.01e-03 2.63e-01
238123 0.171055 1.12e-03 2.89e-01
12724 0.18261689 1.15e-03 2.92e-01
11927 0.1941862 1.16e-03 2.92e-01
60525 0.27810794 1.23e-03 3.06e-01
71743 0.22179089 1.24e-03 3.06e-01
97908 -0.36098899 1.29e-03 3.15e-01
636104 0.21160998 1.34e-03 3.24e-01
26456 0.20811844 1.37e-03 3.26e-01
77048 0.19066325 1.46e-03 3.42e-01
16639 -0.21264346 1.47e-03 3.42e-01
16522 0.26116449 1.54e-03 3.56e-01
80911 0.16909576 1.58e-03 3.60e-01
93722 -0.19532841 1.67e-03 3.77e-01
235323 0.13114654 1.74e-03 3.88e-01
243912 -0.18019513 1.80e-03 3.88e-01
626391 0.38993765 1.83e-03 3.88e-01
17385 -0.19631174 1.84e-03 3.88e-01
74747 -0.18128005 1.86e-03 3.88e-01
72938 0.1921107 1.86e-03 3.88e-01
17076 0.17462636 1.87e-03 3.88e-01
68347 0.17283156 1.88e-03 3.88e-01
100302565 -0.32590127 1.90e-03 3.88e-01
74296 0.17682524 1.90e-03 3.88e-01
102442 0.13230147 1.99e-03 4.01e-01
100504302 0.38843918 2.05e-03 4.04e-01
100310813 0.28757455 2.05e-03 4.04e-01
225994 0.19837039 2.06e-03 4.04e-01
15360 0.23363385 2.09e-03 4.07e-01
56739 -0.16914015 2.35e-03 4.51e-01
110391 0.13913843 2.36e-03 4.51e-01
74114 0.15327028 2.38e-03 4.51e-01
381990 -0.16785806 2.44e-03 4.55e-01
93699 -0.20014064 2.47e-03 4.55e-01
18546 0.23164387 2.48e-03 4.55e-01
65972 0.17845375 2.49e-03 4.55e-01
211429 0.16456094 2.52e-03 4.55e-01
56274 0.14925991 2.54e-03 4.55e-01
66643 0.1920548 2.55e-03 4.55e-01
100042959 -0.16695021 2.62e-03 4.59e-01
54367 0.13133724 2.63e-03 4.59e-01
18771 0.16252266 2.65e-03 4.59e-01
18675 -0.15765147 2.67e-03 4.59e-01
100043194 -0.45759509 2.68e-03 4.59e-01
434117 -0.15843196 2.90e-03 4.93e-01
67468 0.20500637 2.95e-03 4.94e-01
18669 0.19933081 2.96e-03 4.94e-01
735285 -0.21507312 3.01e-03 5.00e-01
76890 0.15326625 3.11e-03 5.02e-01
269198 0.13961578 3.12e-03 5.02e-01
70456 0.18345651 3.13e-03 5.02e-01
72973 0.24939081 3.15e-03 5.02e-01
71687 0.24917463 3.15e-03 5.02e-01
100038381 0.17319271 3.19e-03 5.02e-01
244484 0.20600627 3.24e-03 5.02e-01
30054 0.20344885 3.26e-03 5.02e-01
70266 0.12276257 3.26e-03 5.02e-01
619304 0.13170795 3.26e-03 5.02e-01
321007 0.14983435 3.39e-03 5.17e-01
11600 0.17281012 3.42e-03 5.19e-01
67733 0.16349369 3.50e-03 5.27e-01
208691 0.22913359 3.58e-03 5.33e-01
74629 -0.20212529 3.59e-03 5.33e-01
15452 0.27325456 3.64e-03 5.37e-01
503550 0.15043176 3.68e-03 5.39e-01
207777 0.1459746 3.80e-03 5.50e-01
100038755 -0.18084944 3.81e-03 5.50e-01
56544 -0.18093142 3.92e-03 5.62e-01
67516 0.13698202 3.99e-03 5.67e-01
67120 0.18676114 4.01e-03 5.67e-01
70951 0.16395442 4.12e-03 5.75e-01
57875 0.16394794 4.12e-03 5.75e-01
20184 0.15424828 4.17e-03 5.78e-01
66333 0.23826662 4.19e-03 5.78e-01
66469 0.12507408 4.26e-03 5.84e-01
211001 -0.17329892 4.39e-03 5.97e-01
21354 -0.1662501 4.57e-03 6.18e-01
320770 0.16249198 4.60e-03 6.18e-01
84035 0.1966065 4.67e-03 6.23e-01
72459 0.14811264 4.69e-03 6.23e-01
227095 0.28311598 4.79e-03 6.28e-01
77288 -0.21498066 4.82e-03 6.28e-01
93709 -0.27225784 4.82e-03 6.28e-01
75665 0.12937339 5.04e-03 6.52e-01
71706 -0.1450979 5.12e-03 6.54e-01
12351 0.24063476 5.23e-03 6.54e-01
70291 -0.17665078 5.23e-03 6.54e-01
54160 0.17395019 5.25e-03 6.54e-01
100038371 0.25898207 5.29e-03 6.54e-01
23991 0.15386472 5.33e-03 6.54e-01
66184 0.1621425 5.37e-03 6.54e-01
208366 0.23116822 5.38e-03 6.54e-01
16185 -0.18308209 5.38e-03 6.54e-01
30795 0.14901801 5.42e-03 6.54e-01
52588 0.13025158 5.44e-03 6.54e-01
77809 0.14926226 5.44e-03 6.54e-01
320226 0.16708043 5.45e-03 6.54e-01
218138 0.12434479 5.52e-03 6.57e-01
54614 0.10593733 5.55e-03 6.57e-01
241694 0.12408234 5.57e-03 6.57e-01
12017 0.18405957 5.73e-03 6.66e-01
228598 -0.18485195 5.75e-03 6.66e-01
109652 0.22103615 5.76e-03 6.66e-01
68223 0.18297719 5.77e-03 6.66e-01
228357 0.10960601 5.82e-03 6.68e-01
16885 0.14581946 5.98e-03 6.83e-01
107569 0.18925986 6.15e-03 6.98e-01
258113 -0.19920508 6.22e-03 7.02e-01
226255 0.1288838 6.30e-03 7.02e-01
723852 0.14529091 6.32e-03 7.02e-01
14431 0.16657823 6.34e-03 7.02e-01
319164 0.15270331 6.39e-03 7.02e-01
234854 0.1724227 6.41e-03 7.02e-01
242864 0.17635157 6.45e-03 7.02e-01
66242 -0.12547869 6.47e-03 7.02e-01
387150 0.27134553 6.48e-03 7.02e-01
13876 0.14052138 6.55e-03 7.04e-01
73166 0.13378065 6.57e-03 7.04e-01
75453 -0.13539547 6.60e-03 7.04e-01
12500 -0.16763959 6.68e-03 7.09e-01
15951 0.26133536 6.79e-03 7.12e-01
330921 0.17622959 6.80e-03 7.12e-01
232790 -0.1373656 6.81e-03 7.12e-01
235533 0.22787798 6.97e-03 7.25e-01
20018 0.11711893 7.13e-03 7.26e-01
72477 0.17320538 7.18e-03 7.26e-01
228913 0.15220455 7.19e-03 7.26e-01
12774 -0.12791986 7.20e-03 7.26e-01
19243 0.1472318 7.23e-03 7.26e-01
56295 0.29350305 7.24e-03 7.26e-01
66541 0.20270749 7.28e-03 7.26e-01
11722 0.22620203 7.30e-03 7.26e-01
93710 -0.29082649 7.34e-03 7.26e-01
319655 0.10894037 7.35e-03 7.26e-01
11666 0.16657423 7.36e-03 7.26e-01
217837 0.1210733 7.59e-03 7.39e-01
276919 0.12285119 7.60e-03 7.39e-01
170788 0.16967708 7.62e-03 7.39e-01
791324 -0.11142329 7.64e-03 7.39e-01
93716 -0.24784599 7.69e-03 7.39e-01
225164 0.14523542 7.73e-03 7.39e-01
100041449 -0.38874303 7.75e-03 7.39e-01
76138 0.15386324 7.78e-03 7.39e-01
12626 0.13678556 7.80e-03 7.39e-01
209212 0.14672526 7.88e-03 7.39e-01
68738 0.15365798 7.89e-03 7.39e-01
12371 0.12779222 7.90e-03 7.39e-01
387154 0.33778662 7.99e-03 7.42e-01
17688 0.16415933 8.02e-03 7.42e-01
236539 -0.13824075 8.07e-03 7.42e-01
330817 0.13659862 8.10e-03 7.42e-01
22035 0.19209393 8.12e-03 7.42e-01
80907 0.12594462 8.17e-03 7.42e-01
229615 -0.15950041 8.19e-03 7.42e-01
110696 -0.24750766 8.22e-03 7.42e-01
435376 0.13324216 8.31e-03 7.46e-01
12447 0.12695991 8.33e-03 7.46e-01
382156 -0.23289304 8.47e-03 7.53e-01
68526 0.15827915 8.48e-03 7.53e-01
216558 0.13594106 8.61e-03 7.59e-01
628398 -0.14276623 8.62e-03 7.59e-01
217071 -0.15615233 8.66e-03 7.60e-01
56334 0.31737033 8.76e-03 7.65e-01
72479 0.20454991 8.96e-03 7.79e-01
280668 0.19064761 9.07e-03 7.86e-01
433466 0.21572606 9.14e-03 7.89e-01
66132 -0.13423168 9.20e-03 7.90e-01
68051 0.1397333 9.27e-03 7.90e-01
12964 -0.13133075 9.29e-03 7.90e-01
50769 0.14863734 9.31e-03 7.90e-01
69225 0.15174152 9.38e-03 7.93e-01
76469 0.11505992 9.44e-03 7.95e-01
217480 0.15797394 9.55e-03 7.96e-01
100127111 0.14166307 9.56e-03 7.96e-01
238024 0.13205633 9.57e-03 7.96e-01
75050 0.14522624 9.74e-03 8.08e-01
69361 -0.16754707 9.94e-03 8.16e-01
101772 -0.12581468 9.95e-03 8.16e-01
68818 0.11452905 9.96e-03 8.16e-01
27494 0.11385086 1.00e-02 8.17e-01
233016 0.19075234 1.01e-02 8.17e-01
13206 0.11928578 1.01e-02 8.17e-01
353499 0.18542302 1.02e-02 8.17e-01
100217424 0.2564481 1.02e-02 8.17e-01
11534 0.11350364 1.02e-02 8.17e-01
241525 -0.11777202 1.02e-02 8.17e-01
80876 -0.18717639 1.03e-02 8.17e-01
67903 0.13789775 1.04e-02 8.17e-01
74256 0.1342492 1.04e-02 8.17e-01
17886 0.12205864 1.04e-02 8.17e-01
237211 0.10780113 1.05e-02 8.17e-01
67164 0.11138492 1.06e-02 8.17e-01
433273 -0.20760155 1.06e-02 8.17e-01
93717 -0.16993159 1.06e-02 8.17e-01
210573 0.14781497 1.06e-02 8.17e-01
104130 -0.14197264 1.06e-02 8.17e-01
106757 0.13312785 1.07e-02 8.17e-01
232314 0.14494488 1.07e-02 8.17e-01
114128 0.1390033 1.08e-02 8.17e-01
237859 0.13264623 1.08e-02 8.17e-01
68777 0.12555197 1.08e-02 8.17e-01
72096 0.16972898 1.09e-02 8.19e-01
78797 -0.10564702 1.09e-02 8.20e-01
77836 -0.12411333 1.10e-02 8.22e-01
67963 0.17148257 1.12e-02 8.32e-01
66758 -0.1445287 1.12e-02 8.34e-01
66566 0.11470065 1.13e-02 8.36e-01
50994 0.11877087 1.15e-02 8.46e-01
75905 0.12547493 1.15e-02 8.46e-01
22239 0.13202401 1.16e-02 8.46e-01
66357 0.11612112 1.16e-02 8.46e-01
214917 0.10653225 1.18e-02 8.54e-01
107951 0.17972043 1.19e-02 8.59e-01
80291 0.1282775 1.19e-02 8.60e-01
68628 0.14535265 1.20e-02 8.63e-01
208076 -0.14649411 1.20e-02 8.63e-01
436332 -0.17634148 1.22e-02 8.64e-01
24074 0.14051698 1.22e-02 8.64e-01
53381 0.20633609 1.22e-02 8.64e-01
98999 0.14932941 1.23e-02 8.67e-01
68099 0.1213949 1.24e-02 8.74e-01
70843 -0.13969694 1.24e-02 8.74e-01
100009600 -0.17132813 1.25e-02 8.78e-01
69713 0.40310965 1.27e-02 8.83e-01
19652 0.16625661 1.27e-02 8.83e-01
231580 -0.10590032 1.27e-02 8.83e-01
72899 0.12993196 1.29e-02 8.87e-01
100503426 0.19069647 1.29e-02 8.87e-01
266781 -0.10841388 1.29e-02 8.87e-01
69668 0.16881339 1.30e-02 8.87e-01
18775 -0.20001237 1.31e-02 8.94e-01
234847 0.13235092 1.32e-02 8.94e-01
75739 0.20843884 1.34e-02 8.94e-01
23992 0.11785491 1.34e-02 8.94e-01
227700 0.11386092 1.34e-02 8.94e-01
238896 -0.10244003 1.35e-02 8.94e-01
54721 0.11577935 1.35e-02 8.94e-01
67117 0.1516972 1.35e-02 8.94e-01
20220 0.15341049 1.36e-02 8.94e-01
22698 0.11915054 1.36e-02 8.94e-01
229906 0.12605551 1.36e-02 8.94e-01
72149 0.11121122 1.36e-02 8.94e-01
209837 0.17259439 1.36e-02 8.94e-01
627191 -0.12821983 1.37e-02 8.94e-01
545477 -0.13413683 1.37e-02 8.98e-01
71774 -0.14825861 1.38e-02 9.00e-01
53312 0.0968836 1.39e-02 9.00e-01
100302498 0.15381765 1.40e-02 9.06e-01
240028 0.09849934 1.40e-02 9.06e-01
77864 -0.13227162 1.42e-02 9.07e-01
246747 -0.10435411 1.42e-02 9.07e-01
19094 0.2393236 1.42e-02 9.07e-01
67109 -0.11504096 1.42e-02 9.07e-01
17187 -0.11412237 1.44e-02 9.13e-01
319263 0.11946918 1.44e-02 9.13e-01
338346 -0.13523455 1.45e-02 9.14e-01
22294 -0.32855184 1.45e-02 9.14e-01
26876 -0.11311351 1.46e-02 9.15e-01
546663 0.17202786 1.47e-02 9.15e-01
12663 0.18546602 1.48e-02 9.15e-01
258852 -0.16703042 1.48e-02 9.15e-01
84652 0.13394088 1.48e-02 9.15e-01
110094 0.19445221 1.49e-02 9.15e-01
76478 0.15194335 1.49e-02 9.15e-01
66898 -0.10074036 1.50e-02 9.15e-01
230393 0.12827567 1.50e-02 9.15e-01
235606 0.12537956 1.51e-02 9.15e-01
211135 0.09761758 1.51e-02 9.15e-01
60534 -0.1031243 1.51e-02 9.15e-01
227522 -0.09493117 1.52e-02 9.15e-01
68778 0.13625233 1.52e-02 9.15e-01
634322 -0.38781183 1.52e-02 9.15e-01
17777 0.14121187 1.53e-02 9.18e-01
18037 0.15474376 1.53e-02 9.18e-01
171405 0.15123111 1.56e-02 9.28e-01
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