Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000166
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Mus musculus
Tissue Brain
Cell Line Cerebellum
Platform GPL13730
Accession GSE99135
GEO Title Life Span Analysis of Brain Development, Gene Expression and Behavioral PheNtypes in the Ts1Cje, Ts65Dn and Dp16 Mouse Models of Down Syndrome
PMID 29716957
Article Title Lifespan analysis of brain development, gene expression and behavioral pheNtypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome
Author Aziz N, Guedj F, Olmos-SerraN LJ, Pennings JL, Siegel AE, Bianchi DW, Haydar TF
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi
Pub Link -
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE99nnn/GSE99135/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

Gene Symbol Gene Title logFC P-value P-adj
13411 2.03987954 4.11e-13 8.72e-09
207781 0.67083227 5.97e-08 6.33e-04
16443 0.61134216 1.03e-07 7.31e-04
246313 1.33344196 2.00e-07 9.32e-04
320910 -0.9087327 2.38e-07 9.32e-04
15975 0.54574972 2.64e-07 9.32e-04
104015 0.59963602 4.69e-07 1.36e-03
19106 0.76604594 5.11e-07 1.36e-03
15976 0.67595118 1.41e-06 2.46e-03
20846 0.64315825 1.49e-06 2.46e-03
16440 -0.58434925 1.52e-06 2.46e-03
12845 -0.71233057 1.55e-06 2.46e-03
77975 0.51710937 1.60e-06 2.46e-03
15980 0.51779843 1.63e-06 2.46e-03
16155 0.59816579 2.18e-06 3.08e-03
13179 0.49859741 2.69e-06 3.56e-03
20658 0.54991508 3.40e-06 4.18e-03
52430 -0.60041238 3.54e-06 4.18e-03
66609 0.50898781 6.68e-06 6.89e-03
55990 0.69683776 6.77e-06 6.89e-03
67367 0.54329644 6.82e-06 6.89e-03
23833 0.60404782 7.48e-06 7.04e-03
70028 0.46348179 7.63e-06 7.04e-03
60364 0.56736919 8.22e-06 7.27e-03
93871 0.59439275 9.21e-06 7.68e-03
13185 0.51145648 9.41e-06 7.68e-03
67775 0.89271293 1.15e-05 8.61e-03
20688 -0.56030599 1.18e-05 8.61e-03
71446 0.50066774 1.19e-05 8.61e-03
23872 0.49815614 1.22e-05 8.61e-03
22169 0.51872173 1.44e-05 9.77e-03
23962 1.03779661 1.48e-05 9.77e-03
15957 1.30382831 1.54e-05 9.77e-03
53318 -0.52197447 1.56e-05 9.77e-03
16819 0.68746128 1.80e-05 1.09e-02
230073 0.66888204 1.86e-05 1.10e-02
20684 0.49791167 2.02e-05 1.15e-02
23876 0.5899839 2.06e-05 1.15e-02
338467 0.56030558 2.15e-05 1.17e-02
26559 0.48227941 2.31e-05 1.21e-02
78781 0.50023386 2.34e-05 1.21e-02
226691 0.57605642 2.42e-05 1.23e-02
14450 0.47398063 2.72e-05 1.33e-02
67088 -0.37614885 2.75e-05 1.33e-02
13040 0.52411602 3.16e-05 1.46e-02
17858 0.7490168 3.31e-05 1.46e-02
15360 0.67912951 3.32e-05 1.46e-02
217951 -0.51208844 3.33e-05 1.46e-02
218544 0.38729724 3.38e-05 1.46e-02
15944 0.82704131 3.46e-05 1.47e-02
320429 0.46566318 4.20e-05 1.75e-02
24110 0.93510256 4.42e-05 1.80e-02
93961 0.56901938 5.09e-05 2.01e-02
19039 0.86467709 5.12e-05 2.01e-02
15959 0.99493278 5.51e-05 2.13e-02
22129 0.36876913 5.69e-05 2.16e-02
54720 0.40231777 6.17e-05 2.30e-02
17304 -0.46493386 6.56e-05 2.38e-02
12268 0.51902973 6.65e-05 2.38e-02
52668 0.57723839 6.72e-05 2.38e-02
207932 0.36424516 7.63e-05 2.58e-02
672511 0.54873508 7.65e-05 2.58e-02
16145 0.57418351 7.75e-05 2.58e-02
56088 0.42648424 7.77e-05 2.58e-02
13508 0.6856255 7.96e-05 2.59e-02
76933 0.76239768 8.04e-05 2.59e-02
13548 0.36150019 8.35e-05 2.65e-02
667370 0.91874591 8.62e-05 2.69e-02
11520 -0.33957961 8.73e-05 2.69e-02
110948 0.40820038 9.04e-05 2.70e-02
333182 -0.42384528 9.09e-05 2.70e-02
60440 0.59910352 9.17e-05 2.70e-02
246738 0.62479747 9.43e-05 2.73e-02
15203 0.34900338 9.51e-05 2.73e-02
381831 -0.4549996 9.70e-05 2.75e-02
240327 0.50200733 9.97e-05 2.78e-02
12364 -0.49981881 1.02e-04 2.80e-02
209195 0.65058354 1.03e-04 2.80e-02
280667 -0.41143261 1.17e-04 3.13e-02
18600 -0.54915529 1.18e-04 3.14e-02
67293 -1.01790867 1.26e-04 3.28e-02
24059 -0.64622955 1.27e-04 3.28e-02
71760 0.5969988 1.32e-04 3.37e-02
23961 0.61403708 1.39e-04 3.50e-02
114565 0.33995908 1.43e-04 3.56e-02
28080 0.40837243 1.46e-04 3.59e-02
433752 0.34273554 1.52e-04 3.70e-02
11522 0.31667046 1.59e-04 3.82e-02
80718 0.4386041 1.63e-04 3.88e-02
195208 0.32342426 1.69e-04 3.99e-02
16391 0.64481156 1.76e-04 4.12e-02
12408 0.42213767 2.04e-04 4.71e-02
626391 0.59338049 2.14e-04 4.88e-02
436493 0.47937346 2.18e-04 4.93e-02
12411 -0.35400268 2.22e-04 4.97e-02
230393 0.30465319 2.28e-04 5.03e-02
22017 0.33029654 2.33e-04 5.10e-02
19225 0.62104892 2.40e-04 5.20e-02
68001 0.37198092 2.47e-04 5.30e-02
71586 0.50564685 2.54e-04 5.39e-02
114713 0.31569398 2.64e-04 5.55e-02
229900 0.64423738 2.69e-04 5.60e-02
54123 0.82044371 2.74e-04 5.64e-02
19771 -0.60745112 2.77e-04 5.64e-02
100129 -0.37622883 2.79e-04 5.64e-02
14451 -0.42500072 2.87e-04 5.75e-02
58185 0.61464009 3.04e-04 6.03e-02
11606 -0.44806263 3.17e-04 6.22e-02
17153 0.34380548 3.33e-04 6.44e-02
20315 0.32937258 3.34e-04 6.44e-02
246316 0.30472343 3.53e-04 6.66e-02
12628 0.39333482 3.55e-04 6.66e-02
13361 0.28702103 3.56e-04 6.66e-02
67513 -0.36245985 3.58e-04 6.66e-02
17105 0.53164716 3.63e-04 6.70e-02
12505 -0.33947505 3.85e-04 7.05e-02
53325 -0.36772127 3.99e-04 7.23e-02
12663 0.36839872 4.07e-04 7.32e-02
16600 -0.48718981 4.25e-04 7.59e-02
547253 0.4638348 4.40e-04 7.76e-02
217069 0.47677914 4.42e-04 7.76e-02
74199 0.32987596 4.47e-04 7.77e-02
18399 -0.31527547 4.56e-04 7.86e-02
17476 0.49533086 5.15e-04 8.82e-02
68936 0.31784313 5.47e-04 9.28e-02
234311 0.44548432 5.61e-04 9.44e-02
12010 0.40136435 5.79e-04 9.67e-02
16409 0.41182375 5.83e-04 9.67e-02
544710 -0.42894942 6.17e-04 1.01e-01
258628 -0.44613503 6.26e-04 1.02e-01
384732 -0.53842132 6.37e-04 1.03e-01
65963 -0.31189193 6.54e-04 1.05e-01
13731 -0.39048627 6.69e-04 1.07e-01
72136 -0.26658033 6.74e-04 1.07e-01
654810 -0.70524742 6.84e-04 1.07e-01
209200 0.46301926 6.91e-04 1.08e-01
404284 -0.64962375 6.97e-04 1.08e-01
108653 0.40057516 7.37e-04 1.13e-01
257664 -0.60559822 7.44e-04 1.13e-01
66578 0.46925936 7.47e-04 1.13e-01
258755 -0.37502495 7.78e-04 1.17e-01
234365 -0.28839234 7.93e-04 1.19e-01
26931 0.29853407 8.02e-04 1.19e-01
20128 0.55704219 8.11e-04 1.19e-01
67020 -0.29460212 8.17e-04 1.20e-01
224907 -0.25274664 8.32e-04 1.20e-01
239554 -0.29741756 8.33e-04 1.20e-01
55932 0.6917628 8.63e-04 1.24e-01
13491 -0.27334911 8.86e-04 1.25e-01
57264 -0.27157736 8.87e-04 1.25e-01
19224 -0.36325407 8.90e-04 1.25e-01
636808 0.31650545 8.97e-04 1.25e-01
75209 0.36581924 9.08e-04 1.25e-01
12160 0.36491565 9.10e-04 1.25e-01
20897 -0.41251591 9.20e-04 1.26e-01
230379 0.35644503 9.27e-04 1.26e-01
75071 -0.36937813 9.47e-04 1.28e-01
244202 0.2945542 9.73e-04 1.31e-01
18609 -0.35658575 1.01e-03 1.34e-01
433292 -0.2900548 1.02e-03 1.35e-01
15160 -0.30692449 1.04e-03 1.37e-01
22772 -0.25643396 1.05e-03 1.37e-01
16010 0.29945669 1.06e-03 1.37e-01
19193 -0.46040776 1.07e-03 1.37e-01
104362 -0.28665116 1.07e-03 1.37e-01
224079 0.29602792 1.07e-03 1.37e-01
73827 -0.27949223 1.11e-03 1.41e-01
223696 0.39196427 1.12e-03 1.41e-01
74747 -0.30985693 1.12e-03 1.41e-01
631323 0.31542159 1.15e-03 1.43e-01
100040608 -0.28040149 1.19e-03 1.48e-01
258035 -0.37603386 1.21e-03 1.49e-01
433256 0.30069451 1.24e-03 1.51e-01
327959 0.46234587 1.24e-03 1.51e-01
121022 0.32155918 1.25e-03 1.51e-01
15040 0.35442043 1.26e-03 1.51e-01
234915 0.27842444 1.26e-03 1.51e-01
67138 0.42113597 1.27e-03 1.51e-01
19893 0.32991562 1.27e-03 1.51e-01
243764 0.33864639 1.28e-03 1.51e-01
22288 0.28325043 1.30e-03 1.52e-01
723904 -0.29330916 1.30e-03 1.52e-01
56771 -0.23983527 1.32e-03 1.53e-01
53970 -0.25366561 1.33e-03 1.53e-01
434784 -0.47068375 1.34e-03 1.53e-01
19144 -0.33087085 1.34e-03 1.53e-01
14130 0.28854253 1.36e-03 1.54e-01
78779 -0.36023671 1.37e-03 1.55e-01
18795 0.23763363 1.38e-03 1.55e-01
13875 -0.29465051 1.41e-03 1.56e-01
330409 -0.34007073 1.41e-03 1.56e-01
72003 -0.31791081 1.41e-03 1.56e-01
66333 0.28742352 1.42e-03 1.56e-01
21380 -0.31356517 1.44e-03 1.57e-01
243881 -0.29841579 1.44e-03 1.57e-01
117599 0.28704269 1.45e-03 1.57e-01
72014 -0.31235648 1.47e-03 1.58e-01
14972 0.43209279 1.48e-03 1.58e-01
109272 0.36572722 1.49e-03 1.58e-01
54396 0.54572321 1.49e-03 1.58e-01
15958 0.37050934 1.50e-03 1.58e-01
56214 -0.29743022 1.50e-03 1.58e-01
17472 0.62065836 1.52e-03 1.59e-01
243771 0.32009017 1.54e-03 1.60e-01
629756 -0.2603116 1.55e-03 1.61e-01
227960 0.42470211 1.56e-03 1.61e-01
237246 0.38144372 1.58e-03 1.62e-01
13636 0.25358429 1.58e-03 1.62e-01
212518 -0.29658876 1.61e-03 1.63e-01
19128 0.28598894 1.63e-03 1.65e-01
269784 0.24014229 1.65e-03 1.66e-01
20342 -0.33562405 1.68e-03 1.66e-01
77048 0.24970315 1.68e-03 1.66e-01
74087 -0.24375765 1.68e-03 1.66e-01
224022 -0.25858623 1.69e-03 1.66e-01
399566 -0.26345006 1.69e-03 1.66e-01
170757 0.23852617 1.70e-03 1.66e-01
57890 -0.31129749 1.71e-03 1.67e-01
20969 -0.30398745 1.74e-03 1.68e-01
434040 -0.37378392 1.76e-03 1.70e-01
433801 0.63064624 1.78e-03 1.71e-01
13176 0.38085029 1.80e-03 1.72e-01
12494 0.36614351 1.80e-03 1.72e-01
13618 -0.27767567 1.82e-03 1.72e-01
436523 -0.24006522 1.82e-03 1.72e-01
18414 0.33834896 1.84e-03 1.73e-01
224432 0.3463802 1.85e-03 1.73e-01
83558 -0.22870212 1.90e-03 1.75e-01
70603 -0.28222294 1.91e-03 1.75e-01
227058 -0.39031611 1.91e-03 1.75e-01
11815 0.33238751 1.91e-03 1.75e-01
258500 -0.35301064 1.92e-03 1.75e-01
114229 -0.25471021 1.94e-03 1.77e-01
22773 -0.41163178 1.95e-03 1.77e-01
54445 0.26736723 1.97e-03 1.78e-01
65079 -0.25041185 2.00e-03 1.80e-01
80861 0.36003284 2.01e-03 1.80e-01
544974 -0.27959755 2.09e-03 1.86e-01
104245 0.35648604 2.09e-03 1.86e-01
104445 -0.31118493 2.12e-03 1.87e-01
15312 0.29990065 2.13e-03 1.87e-01
217116 -0.23060911 2.16e-03 1.89e-01
108672 0.30033873 2.16e-03 1.89e-01
654820 0.7218747 2.19e-03 1.90e-01
93889 0.31021411 2.19e-03 1.90e-01
216867 -0.27744835 2.22e-03 1.92e-01
11690 0.26788859 2.30e-03 1.97e-01
216835 -0.27925068 2.30e-03 1.97e-01
76785 0.43600406 2.31e-03 1.97e-01
76293 -0.29980481 2.37e-03 2.01e-01
170761 -0.28223061 2.38e-03 2.01e-01
242705 -0.26957532 2.38e-03 2.01e-01
246256 0.31802341 2.46e-03 2.06e-01
18973 0.25537523 2.52e-03 2.10e-01
60613 -0.2546526 2.52e-03 2.10e-01
216393 -0.39362297 2.55e-03 2.11e-01
12534 -0.2388623 2.57e-03 2.12e-01
236537 -0.30406498 2.61e-03 2.15e-01
15925 0.46011132 2.66e-03 2.18e-01
192734 -0.28296676 2.67e-03 2.18e-01
71395 -0.26787142 2.69e-03 2.19e-01
16818 -0.2778825 2.72e-03 2.20e-01
69149 0.26052032 2.72e-03 2.20e-01
22422 -0.26865354 2.86e-03 2.30e-01
56711 0.39427585 2.91e-03 2.32e-01
239405 -0.34771593 2.91e-03 2.32e-01
791327 0.33785805 2.93e-03 2.33e-01
12955 -0.27265584 2.97e-03 2.35e-01
381308 1.16979922 2.98e-03 2.35e-01
76924 -0.30797966 3.01e-03 2.35e-01
258348 -0.29705217 3.02e-03 2.35e-01
380684 0.23650508 3.02e-03 2.35e-01
72780 -0.27055866 3.03e-03 2.35e-01
258601 -0.23370902 3.06e-03 2.37e-01
93881 0.28456249 3.10e-03 2.39e-01
258121 -0.31578769 3.11e-03 2.39e-01
16522 0.45711636 3.19e-03 2.43e-01
22260 -0.25803231 3.19e-03 2.43e-01
208982 0.23305911 3.21e-03 2.43e-01
53881 0.3497884 3.23e-03 2.43e-01
67211 0.4404781 3.23e-03 2.43e-01
106722 -0.24055689 3.23e-03 2.43e-01
101202 0.25584064 3.27e-03 2.43e-01
17968 0.24543236 3.28e-03 2.43e-01
67399 -0.23554451 3.30e-03 2.43e-01
102920 -0.26670963 3.30e-03 2.43e-01
100115376 -0.40988796 3.30e-03 2.43e-01
276950 0.35737086 3.31e-03 2.43e-01
625054 0.33865375 3.31e-03 2.43e-01
252837 0.31251507 3.32e-03 2.43e-01
627371 0.51998823 3.38e-03 2.46e-01
12583 0.25007536 3.40e-03 2.46e-01
18368 -0.24743099 3.42e-03 2.46e-01
12406 -0.24549464 3.43e-03 2.46e-01
209387 0.47899348 3.43e-03 2.46e-01
71183 -0.24109045 3.45e-03 2.46e-01
99633 0.21515426 3.46e-03 2.46e-01
630579 0.33990981 3.46e-03 2.46e-01
60533 0.4921383 3.51e-03 2.47e-01
16019 0.5515949 3.52e-03 2.47e-01
270058 -0.2235385 3.52e-03 2.47e-01
56720 -0.47507195 3.52e-03 2.47e-01
20302 0.3204218 3.52e-03 2.47e-01
23950 0.33350437 3.55e-03 2.48e-01
214804 -0.21573693 3.60e-03 2.51e-01
54712 0.23618431 3.67e-03 2.54e-01
208076 -0.2847382 3.67e-03 2.54e-01
50769 0.23985393 3.72e-03 2.55e-01
121021 -0.26714855 3.73e-03 2.55e-01
22117 -0.29802889 3.74e-03 2.55e-01
241175 0.26761215 3.74e-03 2.55e-01
241052 -0.24766594 3.75e-03 2.55e-01
12563 0.24702119 3.78e-03 2.56e-01
237831 -0.31729356 3.78e-03 2.56e-01
18349 -0.35056481 3.89e-03 2.62e-01
260305 -0.26853005 3.93e-03 2.63e-01
209268 -0.23678073 3.95e-03 2.63e-01
232560 0.27125263 3.97e-03 2.63e-01
68957 -0.3096795 3.99e-03 2.63e-01
19775 0.20452174 3.99e-03 2.63e-01
18546 0.19951582 3.99e-03 2.63e-01
18631 0.32487162 3.99e-03 2.63e-01
216166 -0.32110577 4.00e-03 2.63e-01
17035 -0.30468685 4.02e-03 2.63e-01
66634 0.28441522 4.04e-03 2.63e-01
54426 -0.27363163 4.04e-03 2.63e-01
13142 -0.27622216 4.09e-03 2.66e-01
75704 -0.25404338 4.11e-03 2.66e-01
140492 -0.2415974 4.14e-03 2.67e-01
320586 0.36030163 4.20e-03 2.69e-01
70086 0.31118593 4.20e-03 2.69e-01
102566 0.245956 4.21e-03 2.69e-01
636791 0.26393052 4.26e-03 2.72e-01
18011 -0.25565452 4.28e-03 2.72e-01
550619 -0.23483557 4.32e-03 2.74e-01
59092 -0.23361518 4.35e-03 2.74e-01
83671 0.30852656 4.36e-03 2.74e-01
54486 0.28958586 4.36e-03 2.74e-01
260423 -0.39354446 4.38e-03 2.74e-01
12369 0.23248147 4.40e-03 2.75e-01
100504302 0.70898838 4.44e-03 2.75e-01
16848 -0.28729016 4.45e-03 2.75e-01
20638 -0.26101877 4.46e-03 2.75e-01
50795 0.2931349 4.47e-03 2.75e-01
64580 0.29332402 4.48e-03 2.75e-01
75667 -0.2657452 4.49e-03 2.75e-01
57275 0.26953568 4.49e-03 2.75e-01
18143 0.29905357 4.58e-03 2.79e-01
18858 -0.28927834 4.58e-03 2.79e-01
78303 -0.37333527 4.64e-03 2.81e-01
74424 -0.22901542 4.67e-03 2.82e-01
56791 0.30397132 4.69e-03 2.82e-01
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280408 -0.11888935 1.67e-01 6.96e-01
100040322 0.21350557 1.67e-01 6.96e-01
11909 0.0921587 1.67e-01 6.96e-01
100038595 0.12178535 1.67e-01 6.96e-01
13131