Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000160
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Mus musculus
Tissue Brain
Cell Line Hippocampus
Platform GPL13730
Accession GSE99135
GEO Title Life Span Analysis of Brain Development, Gene Expression and Behavioral PheNtypes in the Ts1Cje, Ts65Dn and Dp16 Mouse Models of Down Syndrome
PMID 29716957
Article Title Lifespan analysis of brain development, gene expression and behavioral pheNtypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome
Author Aziz N, Guedj F, Olmos-SerraN LJ, Pennings JL, Siegel AE, Bianchi DW, Haydar TF
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi
Pub Link -
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE99nnn/GSE99135/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

<
Gene Symbol Gene Title logFC P-value P-adj
13411 3.5455823 7.17e-18 1.52e-13
320910 -0.8379435 2.85e-09 3.03e-05
217951 -0.6609927 4.23e-08 2.99e-04
13185 0.5803735 2.22e-07 1.18e-03
77975 0.5003222 2.86e-07 1.22e-03
15980 0.4783367 5.02e-07 1.44e-03
71760 0.8212768 5.23e-07 1.44e-03
54720 0.4792299 5.90e-07 1.44e-03
104015 0.4699993 6.66e-07 1.44e-03
15976 0.68755 7.25e-07 1.44e-03
15975 0.511394 8.11e-07 1.44e-03
14450 0.5235563 8.75e-07 1.44e-03
13508 0.567714 8.82e-07 1.44e-03
23872 0.5530509 1.12e-06 1.70e-03
26559 0.5312493 1.64e-06 2.32e-03
20658 0.460873 2.99e-06 3.77e-03
71446 0.47348 3.02e-06 3.77e-03
15360 0.6203014 3.97e-06 4.69e-03
68001 0.4621577 4.54e-06 4.77e-03
246738 0.511987 4.69e-06 4.77e-03
28080 0.4527416 4.71e-06 4.77e-03
17067 0.5110436 5.49e-06 5.29e-03
15473 0.5897572 6.09e-06 5.61e-03
16443 0.4724035 6.57e-06 5.61e-03
330921 0.4072711 6.61e-06 5.61e-03
207781 0.5234565 6.94e-06 5.67e-03
654820 0.8545595 7.69e-06 5.89e-03
13548 0.38228 7.77e-06 5.89e-03
93871 0.4610277 9.07e-06 6.44e-03
338467 0.5859709 9.11e-06 6.44e-03
378460 -0.3428159 1.09e-05 7.50e-03
66609 0.4641597 1.17e-05 7.78e-03
19892 0.573249 1.40e-05 8.98e-03
110948 0.4024951 1.52e-05 9.48e-03
229320 0.3461725 1.64e-05 9.94e-03
16819 0.8162375 2.10e-05 1.24e-02
70028 0.4670992 2.24e-05 1.28e-02
72804 -0.3713169 2.67e-05 1.49e-02
17153 0.3149411 2.85e-05 1.55e-02
68936 0.3825735 2.95e-05 1.57e-02
20688 -0.491512 3.28e-05 1.70e-02
21380 -0.4084515 3.55e-05 1.79e-02
18546 0.3308689 5.20e-05 2.57e-02
22129 0.3233387 5.98e-05 2.89e-02
16155 0.4631892 6.51e-05 3.07e-02
56175 0.4561385 8.75e-05 3.91e-02
67367 0.4682377 8.78e-05 3.91e-02
69282 -0.3548427 8.83e-05 3.91e-02
12408 0.4816103 9.64e-05 4.11e-02
121022 0.3610823 9.68e-05 4.11e-02
16873 -0.3437395 1.01e-04 4.21e-02
16522 0.4485233 1.05e-04 4.30e-02
93961 0.4173167 1.20e-04 4.80e-02
320981 -0.4078043 1.26e-04 4.95e-02
70503 0.4972951 1.49e-04 5.76e-02
207932 0.3378893 1.58e-04 5.91e-02
100124344 -0.3017341 1.59e-04 5.91e-02
56088 0.4785325 1.94e-04 7.12e-02
17304 -0.3972961 2.17e-04 7.79e-02
16816 0.365824 2.21e-04 7.82e-02
114565 0.2901157 2.31e-04 8.05e-02
58185 0.2842477 2.68e-04 9.16e-02
214593 -0.3222752 2.72e-04 9.16e-02
19126 0.378726 2.85e-04 9.42e-02
13164 0.2778915 2.88e-04 9.42e-02
68527 0.3894698 2.97e-04 9.55e-02
57349 0.4372541 3.05e-04 9.62e-02
18313 -0.3567999 3.08e-04 9.62e-02
13876 0.2758541 3.35e-04 1.03e-01
19326 0.4098072 3.44e-04 1.04e-01
94191 0.2883309 3.55e-04 1.06e-01
13070 -0.3915751 3.70e-04 1.09e-01
381741 -0.271725 3.93e-04 1.12e-01
100038509 -0.2870993 3.94e-04 1.12e-01
224432 0.3770578 3.97e-04 1.12e-01
15207 -0.3152571 4.29e-04 1.20e-01
27210 -0.3698379 4.52e-04 1.23e-01
320581 -0.467489 4.53e-04 1.23e-01
791408 -0.3326402 4.74e-04 1.24e-01
72017 0.2753573 4.79e-04 1.24e-01
83555 -0.3728502 4.79e-04 1.24e-01
243911 0.3005801 4.82e-04 1.24e-01
101351 0.3771568 4.84e-04 1.24e-01
12268 0.2737788 5.07e-04 1.28e-01
19309 0.3202266 5.22e-04 1.30e-01
75801 0.5024012 5.29e-04 1.31e-01
71863 -0.2690124 5.51e-04 1.34e-01
224530 -0.3645272 5.95e-04 1.44e-01
258880 -0.2986408 6.14e-04 1.46e-01
434784 -0.3183613 6.25e-04 1.47e-01
110454 0.3961871 6.41e-04 1.49e-01
56615 0.416829 6.45e-04 1.49e-01
66578 0.4695135 6.59e-04 1.50e-01
16371 -0.3136777 6.71e-04 1.50e-01
66333 0.2965081 6.77e-04 1.50e-01
243944 -0.4999346 6.84e-04 1.50e-01
50913 0.3186386 6.85e-04 1.50e-01
29862 -0.3185981 7.05e-04 1.53e-01
111970 0.2559423 7.49e-04 1.60e-01
21936 -0.3130654 7.53e-04 1.60e-01
100216533 -0.3330573 7.81e-04 1.64e-01
52588 0.2650443 8.04e-04 1.66e-01
71147 0.3555571 8.06e-04 1.66e-01
17888 -0.2963052 8.43e-04 1.69e-01
378431 -0.2705785 8.45e-04 1.69e-01
387243 -0.3597177 8.46e-04 1.69e-01
17133 -0.2753463 8.61e-04 1.71e-01
627280 -0.5520304 9.08e-04 1.79e-01
15561 0.4100238 9.20e-04 1.79e-01
217258 0.3611128 9.40e-04 1.80e-01
270156 0.3236226 9.50e-04 1.80e-01
258972 -0.3770187 9.50e-04 1.80e-01
442803 0.3343671 9.66e-04 1.81e-01
19201 0.3754038 9.73e-04 1.81e-01
12411 -0.3368434 9.88e-04 1.82e-01
66323 -0.351886 1.02e-03 1.86e-01
22351 -0.2685269 1.03e-03 1.86e-01
70024 -0.2386316 1.03e-03 1.86e-01
240239 -0.300932 1.06e-03 1.88e-01
70274 -0.2718802 1.07e-03 1.89e-01
68738 0.2872496 1.08e-03 1.89e-01
627967 -0.8420295 1.16e-03 2.01e-01
235952 -0.4825722 1.21e-03 2.09e-01
22229 0.2790366 1.23e-03 2.09e-01
246779 -0.3308324 1.23e-03 2.09e-01
14447 -0.2664134 1.26e-03 2.12e-01
60364 0.3677714 1.32e-03 2.21e-01
14706 -0.27516 1.34e-03 2.21e-01
12614 -0.2380147 1.34e-03 2.21e-01
385343 -0.2625898 1.40e-03 2.28e-01
545260 -0.2902528 1.43e-03 2.28e-01
29866 -0.2411834 1.43e-03 2.28e-01
258456 -0.4621782 1.43e-03 2.28e-01
71425 -0.430085 1.44e-03 2.28e-01
319177 -0.2471898 1.47e-03 2.30e-01
16691 -0.286996 1.49e-03 2.32e-01
53901 0.2869439 1.53e-03 2.36e-01
434782 -0.4764068 1.57e-03 2.40e-01
224753 -0.3437379 1.58e-03 2.40e-01
73603 -0.2595703 1.58e-03 2.40e-01
258949 -0.2560429 1.63e-03 2.45e-01
100040260 -0.6870784 1.68e-03 2.47e-01
14302 -0.2245137 1.69e-03 2.47e-01
74318 0.2368644 1.69e-03 2.47e-01
15424 -0.3078202 1.70e-03 2.47e-01
58210 -0.2894822 1.71e-03 2.47e-01
101772 -0.3181188 1.71e-03 2.47e-01
100217426 -0.3633399 1.74e-03 2.47e-01
74319 -0.273667 1.76e-03 2.47e-01
18600 -0.2751196 1.76e-03 2.47e-01
433481 -0.2912266 1.77e-03 2.47e-01
69066 0.2551916 1.77e-03 2.47e-01
234155 -0.2481194 1.79e-03 2.48e-01
69576 -0.3408206 1.84e-03 2.53e-01
258746 -0.2614572 1.86e-03 2.55e-01
393082 -0.2775026 1.94e-03 2.63e-01
245405 -0.3938147 1.95e-03 2.63e-01
269902 0.3908187 1.96e-03 2.63e-01
233836 -0.2540519 1.99e-03 2.65e-01
70445 -0.2455439 2.01e-03 2.67e-01
624121 -0.3024346 2.11e-03 2.75e-01
113852 -0.2839033 2.12e-03 2.75e-01
100038438 -0.3042441 2.14e-03 2.75e-01
21946 0.276736 2.14e-03 2.75e-01
76487 -0.28189 2.15e-03 2.75e-01
387154 0.4067668 2.15e-03 2.75e-01
751520 -0.3465562 2.17e-03 2.76e-01
11666 0.3142869 2.22e-03 2.80e-01
387176 -0.439513 2.26e-03 2.84e-01
245050 0.265158 2.29e-03 2.84e-01
50914 0.2775244 2.29e-03 2.84e-01
384071 0.2947247 2.31e-03 2.84e-01
279499 -0.2596004 2.31e-03 2.84e-01
100124468 0.3251627 2.39e-03 2.91e-01
219038 -0.2196663 2.42e-03 2.94e-01
319178 -0.3509395 2.48e-03 2.98e-01
258602 -0.4708897 2.49e-03 2.98e-01
100038638 -0.2702932 2.51e-03 2.99e-01
68584 -0.3851175 2.55e-03 3.02e-01
72413 0.353254 2.57e-03 3.03e-01
67509 -0.2353689 2.59e-03 3.04e-01
109575 -0.2701803 2.67e-03 3.11e-01
433638 0.3731005 2.76e-03 3.18e-01
667597 0.48907 2.77e-03 3.18e-01
17225 -0.3221674 2.80e-03 3.18e-01
213449 -0.2348296 2.80e-03 3.18e-01
100217455 -0.3845082 2.82e-03 3.18e-01
12337 0.2506307 2.84e-03 3.18e-01
53419 -0.2778727 2.85e-03 3.18e-01
72040 -0.215665 2.86e-03 3.18e-01
55990 0.3950814 2.88e-03 3.18e-01
432798 0.5354555 2.89e-03 3.18e-01
11814 -0.2604121 2.89e-03 3.18e-01
72381 -0.253688 2.93e-03 3.20e-01
238331 0.2638801 2.95e-03 3.20e-01
75434 -0.2703516 2.96e-03 3.20e-01
268709 0.2917567 2.97e-03 3.20e-01
94226 0.2579306 3.00e-03 3.21e-01
114230 -0.2816886 3.10e-03 3.25e-01
574403 -0.252542 3.10e-03 3.25e-01
71390 -0.2541099 3.12e-03 3.25e-01
53970 -0.2911867 3.13e-03 3.25e-01
16644 -0.2635482 3.16e-03 3.25e-01
71326 -0.3080402 3.18e-03 3.25e-01
68352 -0.2293988 3.19e-03 3.25e-01
64059 -0.3092493 3.20e-03 3.25e-01
75502 -0.2534685 3.21e-03 3.25e-01
620709 -0.2609005 3.21e-03 3.25e-01
11688 0.2472094 3.24e-03 3.25e-01
69454 -0.2298223 3.27e-03 3.25e-01
12489 0.2646651 3.27e-03 3.25e-01
78925 0.2620099 3.27e-03 3.25e-01
66647 0.2362365 3.30e-03 3.25e-01
279067 -0.1868412 3.30e-03 3.25e-01
18816 -0.227242 3.30e-03 3.25e-01
102632 0.2307895 3.31e-03 3.25e-01
11552 -0.2587114 3.32e-03 3.25e-01
320302 -0.2988333 3.38e-03 3.29e-01
16917 -0.2547749 3.41e-03 3.30e-01
76612 0.3458009 3.43e-03 3.31e-01
67119 0.2437636 3.46e-03 3.33e-01
723899 -0.2854751 3.48e-03 3.33e-01
16814 -0.2547361 3.54e-03 3.35e-01
15354 -0.2557824 3.54e-03 3.35e-01
14154 -0.1807726 3.56e-03 3.35e-01
21923 -0.352281 3.56e-03 3.35e-01
791375 -0.2582761 3.62e-03 3.37e-01
11425 -0.3276885 3.63e-03 3.37e-01
26876 -0.2755977 3.65e-03 3.37e-01
18636 -0.2110789 3.67e-03 3.37e-01
114643 0.2817583 3.68e-03 3.37e-01
20766 -0.3161053 3.70e-03 3.37e-01
11937 -0.2384041 3.71e-03 3.37e-01
212503 -0.3032099 3.71e-03 3.37e-01
237831 -0.2518562 3.73e-03 3.37e-01
69060 -0.2734598 3.77e-03 3.39e-01
627569 -0.5058473 3.79e-03 3.39e-01
71020 0.274653 3.80e-03 3.39e-01
22017 0.2880698 3.83e-03 3.40e-01
84035 0.2194736 3.93e-03 3.45e-01
258218 0.332655 3.93e-03 3.45e-01
56635 -0.2206438 3.95e-03 3.45e-01
668310 -0.2558244 3.95e-03 3.45e-01
20684 0.2325395 3.96e-03 3.45e-01
239167 -0.2617971 4.03e-03 3.47e-01
18504 -0.2563021 4.03e-03 3.47e-01
66895 0.2609196 4.04e-03 3.47e-01
333715 -0.2217318 4.05e-03 3.47e-01
64385 0.3727427 4.14e-03 3.51e-01
387216 -0.3581335 4.15e-03 3.51e-01
692245 -0.2816764 4.16e-03 3.51e-01
22362 -0.4207389 4.17e-03 3.51e-01
13850 0.3173175 4.24e-03 3.56e-01
672682 -0.2575711 4.29e-03 3.58e-01
15438 -0.2225995 4.31e-03 3.58e-01
546726 -0.2160189 4.31e-03 3.58e-01
258151 -0.3178086 4.34e-03 3.59e-01
258516 -0.2498426 4.37e-03 3.59e-01
100043580 -0.2112128 4.39e-03 3.60e-01
21412 -0.2062969 4.44e-03 3.61e-01
71208 -0.2460731 4.46e-03 3.61e-01
26367 0.5489402 4.49e-03 3.61e-01
76419 -0.2319123 4.50e-03 3.61e-01
16848 -0.2492254 4.54e-03 3.61e-01
70266 0.2988757 4.56e-03 3.61e-01
75477 -0.1893776 4.57e-03 3.61e-01
108723 -0.2734434 4.57e-03 3.61e-01
99377 -0.2379543 4.58e-03 3.61e-01
72273 -0.241702 4.59e-03 3.61e-01
56739 -0.2217313 4.60e-03 3.61e-01
13813 -0.2895271 4.63e-03 3.61e-01
66727 -0.2505765 4.65e-03 3.61e-01
223227 -0.2103423 4.66e-03 3.61e-01
259122 -0.2953385 4.66e-03 3.61e-01
12937 0.3394305 4.77e-03 3.68e-01
18506 -0.216826 4.88e-03 3.73e-01
73230 -0.2404055 4.88e-03 3.73e-01
664702 -0.3435705 4.89e-03 3.73e-01
243090 -0.2899468 4.92e-03 3.74e-01
16797 -0.2838047 4.95e-03 3.74e-01
72665 -0.2441341 4.96e-03 3.74e-01
619292 -0.3023044 4.98e-03 3.75e-01
20204 -0.2284409 5.03e-03 3.77e-01
66260 -0.2212886 5.04e-03 3.77e-01
329972 -0.2342061 5.07e-03 3.78e-01
217700 0.2278163 5.16e-03 3.80e-01
27389 -0.1971155 5.17e-03 3.80e-01
216749 -0.2932162 5.17e-03 3.80e-01
333424 -0.2482413 5.18e-03 3.80e-01
14525 -0.2351011 5.26e-03 3.85e-01
329626 -0.2626094 5.30e-03 3.86e-01
258095 0.3095932 5.32e-03 3.86e-01
20698 -0.2278468 5.34e-03 3.86e-01
225994 0.4032451 5.35e-03 3.86e-01
23937 -0.2746619 5.38e-03 3.86e-01
669780 -0.2960535 5.39e-03 3.86e-01
67653 -0.2102114 5.42e-03 3.86e-01
382686 0.3624463 5.44e-03 3.86e-01
15925 0.4253512 5.46e-03 3.86e-01
620143 -0.3401548 5.48e-03 3.86e-01
235628 -0.2636355 5.49e-03 3.86e-01
20491 0.2359957 5.50e-03 3.86e-01
258565 -0.3248511 5.51e-03 3.86e-01
243612 -0.261159 5.56e-03 3.87e-01
320159 -0.2172927 5.58e-03 3.87e-01
20514 0.2354501 5.62e-03 3.87e-01
280621 0.2991988 5.64e-03 3.87e-01
225865 -0.2065763 5.65e-03 3.87e-01
116746 -0.2504965 5.68e-03 3.87e-01
18663 -0.1927021 5.69e-03 3.87e-01
67993 0.2551897 5.70e-03 3.87e-01
213084 0.25401 5.71e-03 3.87e-01
12972 0.2259042 5.73e-03 3.87e-01
633640 0.3926344 5.74e-03 3.87e-01
80857 -0.2118336 5.75e-03 3.87e-01
18054 -0.1953318 5.77e-03 3.88e-01
100129 -0.2918755 5.80e-03 3.88e-01
76854 -0.2149014 5.83e-03 3.89e-01
78908 -0.1947449 5.85e-03 3.89e-01
74069 -0.2568841 5.87e-03 3.89e-01
214189 0.2996395 5.89e-03 3.90e-01
14985 -0.250494 5.95e-03 3.92e-01
107526 -0.2197692 6.03e-03 3.93e-01
112418 -0.1932516 6.05e-03 3.93e-01
100041379 -0.2925552 6.06e-03 3.93e-01
70086 0.289576 6.09e-03 3.93e-01
258821 -0.2161315 6.12e-03 3.93e-01
72041 0.2124235 6.12e-03 3.93e-01
244187 -0.3409683 6.13e-03 3.93e-01
18510 -0.2153118 6.14e-03 3.93e-01
71184 -0.2484543 6.17e-03 3.93e-01
241112 -0.2385798 6.21e-03 3.93e-01
15512 0.2160167 6.22e-03 3.93e-01
100312987 -0.1913241 6.23e-03 3.93e-01
435376 0.3069103 6.23e-03 3.93e-01
723903 -0.3242041 6.24e-03 3.93e-01
223513 -0.2520788 6.24e-03 3.93e-01
723834 -0.2869581 6.30e-03 3.94e-01
192201 -0.2497517 6.31e-03 3.94e-01
114675 -0.2062355 6.31e-03 3.94e-01
233870 -0.5683497 6.38e-03 3.97e-01
232973 -0.2100873 6.43e-03 3.97e-01
16480 0.2525279 6.43e-03 3.97e-01
14427 -0.2514224 6.44e-03 3.97e-01
15192 -0.1835841 6.45e-03 3.97e-01
18747 0.2025976 6.48e-03 3.98e-01
791269 -0.4463451 6.52e-03 3.99e-01
791370 -0.2061077 6.57e-03 4.00e-01
116939 0.1777794 6.58e-03 4.00e-01
27209 -0.2013624 6.63e-03 4.02e-01
59091 -0.1881892 6.71e-03 4.05e-01
12514 0.2644547 6.74e-03 4.05e-01
14939 -0.2746843 6.75e-03 4.05e-01
216453 -0.2685341 6.75e-03 4.05e-01
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