Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000141
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue Brain
Cell Line Cerebral cortex
Platform GPL96
Accession GSE5390
GEO Title Expression profiling of human adult postmortem brain tissue from Down syndrome and healthy control subjects
PMID 17950572
Article Title Gene expression profiling in the adult Down syndrome brain
Author Lockstone HE, Harris LW, Swatton JE, Wayland MT, Holland AJ, Bahn S
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5390
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/17950572
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE5nnn/GSE5390/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1007_s_at -3.37934673 -0.864453353 0.011769181 0.056687032
1431_at 2.327144856 0.222662947 0.052835568 0.125818447
1598_g_at 1.853305447 0.182579437 0.106250444 0.19876157
1773_at -3.019921238 -0.247313307 0.019388472 0.07107743
179_at -0.539859614 -0.063731558 0.606033459 0.698186249
200001_at -1.867740882 -0.38279841 0.104022387 0.195772426
200002_at -2.09443899 -0.165016288 0.074480261 0.15623272
200003_s_at -1.647787413 -0.173261289 0.143387619 0.246038357
200004_at -1.784141289 -0.216967337 0.117580874 0.213988328
200005_at -0.604694054 -0.087851326 0.564460629 0.6629794
200008_s_at -3.863241199 -0.95069539 0.006185505 0.044527814
200009_at -0.136917212 -0.029859375 0.894951021 0.923511486
200010_at -2.537774741 -0.367215419 0.038789873 0.104117719
200012_x_at -2.867917999 -0.284904085 0.024063531 0.079708939
200014_s_at -3.280508152 -0.34655476 0.013477617 0.060679322
200015_s_at -2.882492084 -0.671223744 0.023567544 0.078808454
200016_x_at -0.629965574 -0.092156035 0.548720253 0.650024419
200017_at -1.016278195 -0.129779629 0.343329218 0.460050382
200018_at -4.743650846 -0.470560877 0.002098944 0.030871514
200020_at -1.159037664 -0.242513714 0.284446448 0.402567113
200023_s_at -0.722528513 -0.118028551 0.493395788 0.601569284
200024_at -1.547868622 -0.174308687 0.16558002 0.272257185
200029_at -2.234953869 -0.307400218 0.060526832 0.136557286
200030_s_at 0.575345909 0.115110156 0.58307032 0.678842982
200031_s_at -2.046915244 -0.288961655 0.079893317 0.163813009
200032_s_at -0.257434235 -0.034344449 0.804247173 0.856942954
200033_at -2.705484402 -0.3514081 0.030396883 0.089839855
200035_at -0.04796573 -0.005096086 0.963083385 0.973602181
200036_s_at -2.464016591 -0.319953617 0.043210191 0.111121925
200037_s_at 0.262903885 0.040058527 0.800194676 0.853689585
200039_s_at 0.119601016 0.015959191 0.908159411 0.932982114
200040_at -0.709226978 -0.127541743 0.501116199 0.607896202
200041_s_at -2.323488511 -0.420265259 0.053120827 0.126152026
200042_at 0.269935822 0.050033238 0.794994369 0.849610551
200046_at -3.185391929 -0.553240015 0.015374867 0.064610338
200047_s_at -1.699498737 -0.439125645 0.133025792 0.233769946
200049_at -3.615201158 -0.286631996 0.00856469 0.049877491
200050_at -2.095620332 -0.419643673 0.074350458 0.156019372
200052_s_at -1.19721096 -0.245783462 0.270189701 0.387275391
200053_at 3.53262936 0.417275078 0.009563996 0.052225815
200054_at -0.21192051 -0.028941978 0.838207376 0.882043517
200055_at -2.439270265 -0.306694412 0.044806899 0.113507261
200056_s_at -0.474033965 -0.108543101 0.649905239 0.733979475
200059_s_at -3.760037356 -0.863295519 0.007074538 0.046495204
200062_s_at -4.299895235 -0.479375927 0.003567061 0.035757528
200063_s_at -1.127112026 -0.155135095 0.296843705 0.414826753
200064_at -0.020946384 -0.005743721 0.98387299 0.989575052
200065_s_at -0.406771821 -0.061549608 0.696325402 0.772348956
200067_x_at -1.260803594 -0.166809106 0.247775595 0.364653972
200068_s_at -3.16728133 -0.457635151 0.015767459 0.065191243
200069_at -0.969472079 -0.247460311 0.364606258 0.481245598
200070_at -0.755428591 -0.209031227 0.474638215 0.584651952
200071_at -1.316108814 -0.348148125 0.229595727 0.344017846
200074_s_at -1.552776345 -0.190699678 0.164419652 0.271131541
200077_s_at 2.911807601 0.363821728 0.022602249 0.07700711
200078_s_at 1.817812828 0.437299285 0.111926633 0.206199211
200080_s_at -2.177986123 -0.444151769 0.065836169 0.144172382
200081_s_at -2.887129873 -0.563181224 0.02341198 0.078467182
200084_at -3.046397202 -0.327183091 0.018677768 0.07006599
200085_s_at 3.888742513 0.610646313 0.00598509 0.044082488
200086_s_at 2.646731208 0.326723787 0.033098379 0.094412774
200087_s_at 0.343327628 0.055545922 0.741432576 0.80847159
200089_s_at -2.551929414 -0.278851837 0.037996455 0.102787313
200090_at -1.50782954 -0.383634386 0.17533134 0.283465093
200091_s_at 0.53230749 0.087496371 0.610984023 0.70185123
200092_s_at -1.252175649 -0.191474945 0.250720574 0.367284809
200093_s_at 0.993656995 0.238465251 0.353488662 0.470034546
200096_s_at -4.625264441 -1.187880785 0.002411116 0.031811734
200097_s_at -0.707868309 -0.135223577 0.501909192 0.608393037
200098_s_at -0.727071269 -0.122551462 0.490777067 0.599412897
200099_s_at -1.591566213 -0.285604374 0.155508934 0.260518512
200594_x_at -5.480131912 -0.370794748 0.000925841 0.025483257
200595_s_at -1.341618532 -0.311091085 0.22160828 0.334611632
200598_s_at -5.198990995 -1.267669386 0.0012544 0.02747468
200599_s_at -1.396030418 -0.272017453 0.205382501 0.316655113
200600_at -6.620888559 -1.452540581 0.000298461 0.018836462
200601_at -2.444540607 -0.201939089 0.044461831 0.113096185
200602_at -0.141451951 -0.015732801 0.89149774 0.921463474
200603_at -0.971197044 -0.203344992 0.36380452 0.48035863
200604_s_at -2.579992237 -0.773975637 0.036472731 0.099975784
200605_s_at -2.20847879 -0.703001301 0.062938394 0.140054943
200606_at -0.838619671 -0.255990869 0.429386456 0.542835079
200607_s_at -3.865982538 -0.772953551 0.006163614 0.044482948
200608_s_at -1.390158367 -0.252107809 0.20708143 0.318567668
200609_s_at -5.636992489 -0.551500804 0.000785038 0.02403636
200610_s_at 0.657538578 0.120299714 0.531853061 0.634783145
200611_s_at -9.841702428 -0.813623672 2.38E-05 0.01518933
200613_at 1.197493294 0.294629874 0.270086525 0.38717747
200614_at 1.386878038 0.269650539 0.208035934 0.319548488
200615_s_at -5.455770473 -0.819364282 0.000950138 0.025638393
200617_at -3.437018173 -0.361326973 0.010881103 0.0554133
200618_at 1.447351014 0.15060993 0.191055369 0.300701713
200619_at -2.405135969 -0.207287618 0.047109361 0.117061329
200620_at -0.363306448 -0.089316897 0.727099558 0.797227825
200621_at -2.308552706 -0.785970257 0.054302457 0.127594116
200622_x_at 0.099121185 0.025265078 0.923820913 0.945267515
200623_s_at 0.737603343 0.335543087 0.484741061 0.594065869
200624_s_at -3.17016443 -0.655122235 0.015704251 0.065163242
200625_s_at -1.911758057 -0.336900234 0.097505067 0.187141658
200626_s_at -1.100871782 -0.246261089 0.307361682 0.424821578
200627_at -1.926784247 -0.494793741 0.095372715 0.184533402
200628_s_at -1.462656947 -0.430092279 0.186959716 0.296143977
200629_at 0.780478465 0.192562699 0.460682065 0.571198447
200630_x_at 4.185134791 0.680342985 0.004110877 0.037607909
200632_s_at -1.971531296 -0.588546738 0.089289456 0.176342713
200633_at -0.224725449 -0.030367781 0.828611898 0.875603723
200634_at -3.19734892 -0.784082604 0.015121402 0.064055459
200637_s_at -2.786270428 -0.641307614 0.027053065 0.084266763
200638_s_at -0.157756141 -0.051745977 0.879103226 0.913600608
200640_at -0.635199607 -0.157098494 0.545493656 0.647445825
200641_s_at -1.582217295 -0.586655185 0.157614713 0.263212543
200642_at -3.440408788 -0.550434744 0.010831187 0.055285844
200643_at -1.928094268 -0.178881423 0.095188985 0.184320792
200644_at -1.674040496 -0.497387449 0.138035622 0.239406878
200646_s_at -3.190920456 -0.70146602 0.015257113 0.064420644
200647_x_at -0.338473402 -0.064423695 0.744932004 0.810934016
200648_s_at -5.072342336 -1.743871988 0.001443315 0.028430939
200649_at -2.542602059 -0.440614671 0.038517377 0.103785053
200651_at -4.367482859 -0.520432051 0.003284109 0.034971223
200653_s_at 2.426111034 0.477934045 0.045680537 0.115036285
200656_s_at -2.899597408 -0.493013185 0.022999133 0.07779542
200657_at 1.027335621 0.301707281 0.338446963 0.455274269
200658_s_at 0.195968661 0.038499406 0.850202247 0.891203884
200660_at -5.057314973 -1.509021031 0.001467754 0.028550521
200662_s_at 0.459735908 0.148799852 0.659643566 0.741790127
200663_at -3.661502688 -0.45400753 0.008054283 0.048356171
200664_s_at -3.376323559 -1.069000687 0.011817838 0.056743511
200665_s_at -4.426818774 -1.145537277 0.003055978 0.034636977
200666_s_at -1.738901436 -0.561511473 0.125609867 0.224156297
200668_s_at -3.459502189 -0.718662066 0.01055467 0.054788375
200669_s_at -7.109341784 -1.109114191 0.00019208 0.017410107
200671_s_at -3.699638162 -1.390762391 0.007658643 0.047550588
200672_x_at -2.057162431 -0.656303862 0.078694024 0.161802022
200673_at -5.153726809 -0.87761923 0.001318565 0.027769571
200674_s_at -1.694568909 -0.229489417 0.133982306 0.23483375
200675_at -4.338678345 -0.855073367 0.003401561 0.03540875
200676_s_at -3.652811825 -0.314777038 0.008147515 0.048626784
200677_at -5.227168353 -1.42450355 0.001216214 0.027400592
200679_x_at -2.148344855 -0.41474541 0.068781524 0.148317334
200681_at -0.717895569 -0.114258821 0.496075931 0.603558574
200683_s_at -7.273575397 -0.504138675 0.000166506 0.017341756
200684_s_at -2.864937336 -0.38241452 0.024166318 0.079885505
200685_at -0.237419282 -0.042702224 0.819130546 0.868769799
200686_s_at -0.597879523 -0.105404503 0.568750386 0.666713514
200687_s_at -1.846163183 -0.358147708 0.107369848 0.200160608
200689_x_at -2.798168573 -0.414442473 0.026594159 0.083370399
200691_s_at -1.057351586 -0.173266803 0.325469405 0.442340983
200692_s_at -1.029851223 -0.258476572 0.337343888 0.454112055
200693_at -2.193683607 -0.452220913 0.064328017 0.142130751
200695_at -0.915962663 -0.218597262 0.390150016 0.506186688
200696_s_at -2.1423518 -0.673315318 0.069392907 0.148936045
200698_at -3.210839638 -0.659596063 0.014840777 0.0635453
200699_at -0.788750263 -0.206259969 0.456135829 0.567461991
200700_s_at -5.337409154 -1.03741244 0.001078766 0.02635385
200701_at -4.027084516 -1.025642675 0.00501431 0.040899472
200702_s_at -0.209961263 -0.059089118 0.839678207 0.883172902
200703_at -1.320963666 -0.164730338 0.228056528 0.342208033
200704_at -3.466516026 -0.948925148 0.010455013 0.054492644
200705_s_at -1.875345504 -0.28275333 0.102866932 0.194343087
200706_s_at -3.382886273 -0.643457433 0.011712487 0.056610356
200708_at 1.492449157 0.257775406 0.179214634 0.288175401
200709_at -3.725585283 -0.64100316 0.007401535 0.047138101
200710_at -1.891011485 -0.271698952 0.100525787 0.191352171
200711_s_at -0.186990362 -0.023842095 0.856972398 0.896692645
200712_s_at -2.987206316 -0.782903135 0.020306514 0.072756273
200713_s_at -4.020747917 -0.751731396 0.005054803 0.04107074
200718_s_at 1.138434604 0.187561376 0.292397061 0.410471961
200719_at 0.430850679 0.067499194 0.679532911 0.758397512
200722_s_at -5.592070941 -0.950089587 0.000822752 0.024210376
200723_s_at -8.03016263 -1.103417179 8.90E-05 0.015926734
200726_at -1.190227561 -0.218468035 0.272752226 0.389841587
200727_s_at -1.510177138 -0.383859964 0.174745404 0.282805946
200728_at 0.519759954 0.13254524 0.61925752 0.708278579
200729_s_at -2.031727645 -0.559592289 0.081704222 0.166415882
200730_s_at -3.753163573 -0.786702949 0.007138504 0.046705442
200731_s_at -6.387293114 -0.626807171 0.000371752 0.019528106
200732_s_at 0.676555494 0.151187815 0.520409453 0.624853977
200734_s_at 1.32059408 0.338827277 0.228173386 0.342337134
200735_x_at -5.634496279 -0.403560614 0.000787082 0.02403636
200736_s_at -1.072190402 -0.19153825 0.319201629 0.436710121
200737_at 0.676298973 0.223895819 0.520562778 0.624866613
200738_s_at 0.386391512 0.088722304 0.710683144 0.784647881
200739_s_at -2.465907389 -0.656158879 0.043090624 0.110917163
200740_s_at -2.974555505 -0.385893042 0.020673778 0.073550175
200741_s_at -2.250791864 -0.365597706 0.059129011 0.134661867
200742_s_at -9.660035956 -2.053928894 2.69E-05 0.01518933
200743_s_at -3.91836491 -0.855426647 0.005761133 0.043246676
200744_s_at -1.430705547 -0.490574675 0.195600978 0.305950374
200745_s_at -0.140849117 -0.045697338 0.891956664 0.921611135
200746_s_at 1.429886168 0.254498574 0.195827224 0.306096379
200747_s_at -1.412468098 -0.229711476 0.200692443 0.311456052
200748_s_at -4.026647986 -0.497146761 0.005017088 0.040899472
200749_at 1.430168952 0.430484586 0.195749116 0.306096379
200750_s_at 0.277692065 0.084552793 0.789271364 0.844632145
200751_s_at -4.801653874 -1.36770933 0.001962537 0.030255202
200753_x_at -1.190912421 -0.280643118 0.272500022 0.389670295
200754_x_at -1.908947136 -0.346825545 0.097909097 0.187754893
200755_s_at -2.603150984 -0.357314312 0.035263053 0.0979229
200758_s_at -3.907984538 -0.363765161 0.005838554 0.043580272
200760_s_at -2.030614641 -0.580846651 0.081838519 0.166499793
200761_s_at -1.56604333 -0.255139903 0.161320242 0.267530325
200762_at 0.404402231 0.063010455 0.697988059 0.773654344
200763_s_at -2.586267056 -0.360967311 0.036140778 0.099387081
200764_s_at -4.143963728 -0.866101836 0.004327646 0.038148542
200765_x_at -2.815879726 -0.665895474 0.025926133 0.082628224
200766_at -2.289319776 -0.388536457 0.055863508 0.129866516
200768_s_at -0.731422182 -0.142929387 0.488277538 0.597325487
200769_s_at -4.588776897 -1.198218135 0.00251742 0.032300861
200771_at -3.633017575 -0.746936097 0.008364256 0.049337118
200772_x_at -2.812326 -0.705538001 0.026058744 0.082861285
200773_x_at -4.856499455 -0.610701747 0.001842533 0.02987752
200774_at -4.844428713 -0.723000726 0.00186823 0.02987752
200776_s_at -3.798581749 -0.741927507 0.006727205 0.045560407
200777_s_at -1.880140597 -0.246768614 0.102144776 0.193373449
200778_s_at -8.445288588 -1.506655895 6.44E-05 0.015926734
200780_x_at -0.697936971 -0.114868066 0.507730343 0.613424346
200781_s_at -1.726464799 -0.250942664 0.127907074 0.227233504
200782_at -3.788390322 -1.117240999 0.006817202 0.045806811
200783_s_at 1.766073312 0.474416964 0.120726856 0.218212073
200785_s_at -4.144009573 -0.332463972 0.004327398 0.038148542
200786_at 0.7657082 0.158927843 0.468876861 0.578878538
200787_s_at -5.072119493 -0.918427244 0.001443674 0.028430939
200790_at -0.899145643 -0.135076125 0.398448216 0.513287443
200791_s_at -2.317986838 -0.887216034 0.053553012 0.126608694
200792_at 0.762938108 0.104739012 0.470424717 0.580427387
200793_s_at -0.226353961 -0.039443801 0.827393768 0.874558677
200794_x_at -2.382179095 -0.276946951 0.048725759 0.11964274
200796_s_at -2.68450819 -0.258302627 0.031333958 0.091154078
200797_s_at -2.924577643 -0.554940324 0.022194897 0.076368871
200798_x_at -10.92899164 -1.722409454 1.19E-05 0.01518933
200799_at -1.241459951 -0.527172682 0.254419756 0.371137409
200800_s_at -1.385433927 -0.776793611 0.208457374 0.319886164
200802_at 1.089027157 0.323988704 0.312207536 0.430287765
200803_s_at -8.99793352 -1.156308853 4.27E-05 0.015219317
200804_at -3.905378935 -0.527150815 0.005858166 0.043580272
200806_s_at -3.091269349 -1.030451577 0.017535729 0.06828373
200807_s_at -2.030533796 -0.367683465 0.081848282 0.166499793
200808_s_at -1.061534046 -0.164283639 0.323692912 0.440703257
200809_x_at -3.079386551 -0.404957389 0.017830739 0.068798561
200810_s_at 1.417383008 0.538870776 0.19930878 0.309828217
200812_at 0.416247356 0.092127785 0.68969471 0.766503817
200813_s_at 0.035657331 0.00809833 0.972551112 0.980941265
200815_s_at -3.269453595 -0.30269508 0.013684643 0.061091369
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