Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000135
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue Bone marrow
Cell Line AML blasts
Platform GPL570
Accession GSE16677
GEO Title Gene expression profiling of Down Syndrome (DS)-AMKL and Nn-DS AMKL samples
PMID 20679399
Article Title Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis
Author Klusmann JH, Godinho FJ, Heitmann K, Maroz A, Koch ML, Reinhardt D, Orkin SH, Li Z
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16677
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/20679399
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE16nnn/GSE16677/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1053_at 3.97836282 0.630353857 0.004071008 0.067489442
121_at -1.973727792 -0.602681097 0.083858663 0.22873286
1294_at 2.320579457 0.274141328 0.048875198 0.190464699
1316_at -1.936498977 -0.561458297 0.088825151 0.234004782
1552256_a_at 2.731197696 0.580783526 0.025797969 0.152791281
1552257_a_at 9.1090977 2.105947011 1.70E-05 0.00485181
1552258_at -1.128319534 -0.533876288 0.291883405 0.438162081
1552263_at 0.902803939 0.148170795 0.393000987 0.532940253
1552264_a_at 3.083992944 1.085973648 0.015025698 0.122183354
1552274_at 0.41335232 0.093297076 0.690206328 0.783812601
1552275_s_at -0.435860918 -0.015596726 0.67445963 0.771513329
1552277_a_at 0.279086268 0.125139881 0.787257583 0.855630296
1552279_a_at -3.649546693 -0.221509031 0.006498622 0.083476427
1552281_at -0.603171724 -0.106527746 0.563099902 0.680806107
1552287_s_at 0.203584647 0.046891215 0.843761256 0.895442862
1552291_at 1.015485745 0.525108842 0.339598679 0.483905522
1552299_at -1.976478827 -0.499665966 0.08350248 0.22846881
1552301_a_at -1.774541328 -0.284789125 0.113894824 0.264075066
1552302_at 1.210227404 0.28874133 0.260733261 0.408428354
1552306_at -0.665519614 -0.142552919 0.524438258 0.64838862
1552314_a_at -0.15450533 -0.0219692 0.881038112 0.921995428
1552319_a_at -1.650283163 -0.156926285 0.137492503 0.288886602
1552329_at 0.408771198 0.186541906 0.693431302 0.786265058
1552330_at 0.44309553 0.062670104 0.669433942 0.767758546
1552343_s_at -1.624569938 -0.461398413 0.142908749 0.294862251
1552344_s_at 6.907894892 1.593706468 0.000123541 0.01179845
1552347_at 2.769770717 1.274946964 0.024305286 0.149706173
1552348_at -2.11188128 -1.229339657 0.067674904 0.210975103
1552359_at -1.24111026 -0.067736734 0.249722544 0.398428956
1552360_a_at -1.021173521 -0.445548614 0.337056873 0.481691263
1552364_s_at -1.233313066 -0.115584545 0.252465299 0.400894347
1552368_at -1.951787784 -0.514072389 0.08675221 0.231506726
1552370_at 1.980803456 0.5318315 0.082945511 0.228018739
1552373_s_at -0.99614709 -0.219351192 0.34835079 0.492349184
1552375_at -2.036940401 -1.269509368 0.076034016 0.219764025
1552378_s_at -1.475365404 -0.103200821 0.178351317 0.331564141
1552383_at -0.686483469 -0.139523271 0.511811051 0.637925612
1552391_at 1.207941073 0.372978774 0.26156416 0.40922884
1552393_at -1.960534825 -0.121811945 0.085587259 0.230544494
1552398_a_at 0.702003111 0.435536727 0.50258636 0.629989477
1552399_a_at 0.446134731 0.012299067 0.667327947 0.766343601
1552401_a_at -2.681974163 -0.474419694 0.027840699 0.157688885
1552409_a_at -2.174377374 -0.467560094 0.061398208 0.204925494
1552414_at -2.31304433 -0.871711663 0.049453504 0.191101963
1552419_s_at -0.676028721 -0.011703618 0.518084479 0.64314549
1552422_at -1.763427315 -0.876268385 0.115840526 0.265865456
1552423_at -1.90129916 -0.375554156 0.093780047 0.240552591
1552426_a_at -1.011266405 -0.50225882 0.341493735 0.48579463
1552440_at -0.274728018 -0.023054914 0.790486616 0.858046888
1552466_x_at -1.559323087 -0.114146488 0.15753899 0.31032749
1552472_a_at -1.444687446 -0.54134733 0.186547059 0.339975572
1552474_a_at 1.084331961 0.351874761 0.309811167 0.457034237
1552481_s_at -0.397232604 -0.066968771 0.701583522 0.792486564
1552485_at -2.045094135 -0.537277182 0.075077832 0.21892733
1552497_a_at -3.216982985 -0.328457706 0.012294734 0.112866335
1552498_at -1.359992813 -0.413713445 0.210916617 0.364151354
1552499_a_at -2.296995574 -0.62894759 0.050708092 0.192790702
1552507_at -1.342075527 -0.186038457 0.216412417 0.368874597
1552516_a_at 1.27880544 0.877364848 0.236812114 0.38676904
1552520_at -0.740205046 -0.121551307 0.480332361 0.611437949
1552521_a_at -1.591019508 -0.167763892 0.15026956 0.30271196
1552522_at -3.291950907 -1.167290887 0.01099 0.107792003
1552523_a_at -1.855614265 -1.030732994 0.100605884 0.248430481
1552524_at -1.642918129 -0.054524371 0.13902428 0.290584582
1552536_at -0.706891919 -0.151430467 0.499702402 0.627454728
1552541_at 0.212668946 0.042381377 0.83690417 0.89058867
1552543_a_at 1.886294105 0.410442999 0.09597171 0.243188893
1552544_at -1.520629919 -0.194632055 0.166843331 0.319594809
1552548_at -2.248713159 -0.332575358 0.054676991 0.197186504
1552557_a_at -1.119866438 -0.175800182 0.295262641 0.44168082
1552558_a_at 0.863107719 0.032437393 0.413204074 0.552192554
1552568_at 1.016230093 0.083661682 0.339265204 0.483606998
1552570_at -1.652967386 -0.287790926 0.136938111 0.288276313
1552573_s_at -1.689567709 -0.529882194 0.1295817 0.280288174
1552576_at -3.202842106 -0.777968251 0.012558601 0.114241048
1552579_a_at -2.108268292 -0.966125142 0.068056438 0.21130164
1552585_s_at -2.113176745 -0.503565421 0.067538613 0.210814971
1552587_at -2.272529977 -1.335386508 0.052681996 0.194449121
1552607_at -3.041093603 -0.565155663 0.016036609 0.125538779
1552608_at -1.22098627 -0.259357057 0.256852539 0.405013306
1552610_a_at 2.130466675 0.578980018 0.06574518 0.209283969
1552611_a_at 2.38163531 0.766504007 0.044432125 0.184301083
1552612_at 1.059295458 0.779097279 0.320397623 0.466427039
1552613_s_at 2.834356045 1.747594509 0.022002208 0.1435242
1552615_at -1.809885612 -0.220719296 0.107909505 0.256779609
1552617_a_at 1.928581294 0.566446083 0.089917301 0.235453402
1552618_at 0.258762033 0.033737226 0.802352197 0.866448987
1552620_at -1.906149706 -0.693065668 0.093081861 0.23957897
1552621_at -0.591154733 -0.438241768 0.570737698 0.687575543
1552622_s_at -0.749401958 -0.361475837 0.475071938 0.606589187
1552623_at 3.683893042 1.599284984 0.006184362 0.081975818
1552625_a_at 0.430434174 0.052211807 0.678240904 0.774346537
1552626_a_at -1.706467093 -0.117163644 0.126310019 0.276874157
1552627_a_at 1.026080138 0.159720545 0.33487593 0.479528142
1552628_a_at 2.222537981 1.560174364 0.056956166 0.199965888
1552632_a_at -0.974726623 -0.054069998 0.358243972 0.5012662
1552634_a_at 0.94268881 0.502165245 0.373432799 0.515153205
1552643_at -2.219561285 -0.855639718 0.057221252 0.200405856
1552644_a_at 1.826254752 0.288987165 0.10523921 0.253857055
1552646_at -1.988823924 -0.650505728 0.081922042 0.226758951
1552648_a_at 1.053226443 0.2673111 0.323006023 0.468625602
1552656_s_at 0.322148365 0.067984512 0.755597465 0.832721652
1552657_a_at -1.852079685 -0.415621897 0.101153258 0.249128788
1552658_a_at -1.801716717 -0.293101641 0.109265917 0.258573266
1552661_at -1.649005195 -0.277830357 0.137757176 0.289242402
1552663_a_at -1.809228492 -0.486503139 0.108018027 0.256950975
1552664_at 0.927448709 0.329664107 0.38082342 0.521712036
1552665_at -1.768747695 -0.656091673 0.11490524 0.265151847
1552674_at -2.006059893 -0.794978939 0.079763776 0.224039479
1552675_at -0.428832092 -0.023822108 0.679359074 0.775363547
1552676_at -0.722887182 -0.067065936 0.49034038 0.619936762
1552677_a_at 0.738829145 0.174587401 0.481122602 0.612044434
1552680_a_at -1.793073271 -0.089211572 0.110718627 0.260495267
1552682_a_at -2.102060065 -0.315040823 0.06871696 0.211949093
1552687_a_at -1.948559325 -0.416780341 0.087186029 0.232044504
1552689_at -0.226543176 -0.013751396 0.826460279 0.883572467
1552691_at 0.961958361 0.132476153 0.364240875 0.506595021
1552695_a_at -3.158804604 -0.380392285 0.013419126 0.117330342
1552696_at -1.146794241 -0.434129596 0.284606123 0.431411945
1552701_a_at -1.333842786 -0.527896174 0.218978701 0.371116708
1552703_s_at 1.243822473 0.557604046 0.24877434 0.397787905
1552708_a_at -2.280809694 -1.132084834 0.052005557 0.193929387
1552711_a_at 1.725852752 0.129546207 0.122651612 0.272916766
1552712_a_at -1.965892138 -0.644344977 0.084881218 0.229853105
1552713_a_at -1.594293019 -0.621026459 0.149536435 0.301836331
1552714_at -1.616906553 -0.320310419 0.144560407 0.296677307
1552717_s_at -0.581209592 -0.155233877 0.577103089 0.692554142
1552719_at -1.281241247 -0.090974696 0.235997566 0.386062158
1552729_at -1.214661887 -0.349030799 0.259127904 0.407136065
1552733_at -1.208745018 -0.371954584 0.261271741 0.409028403
1552734_at -2.762374746 -0.505805215 0.024584442 0.15058384
1552735_at -2.47701136 -0.917614048 0.038289626 0.176228492
1552736_a_at -3.772660754 -0.775685554 0.005444909 0.077835066
1552738_a_at -1.386493915 -0.705191434 0.203009249 0.356463928
1552749_a_at -3.085555954 -0.279819202 0.014990148 0.12195397
1552751_a_at -1.61947119 -0.078102256 0.144005726 0.296034056
1552752_a_at -0.421253461 -0.087556713 0.684659979 0.779491552
1552754_a_at -1.5170736 -0.379887635 0.167722821 0.320457935
1552758_at -2.240628058 -0.340143984 0.055371159 0.198186509
1552760_at -3.406943494 -0.124741973 0.009264888 0.099016449
1552763_at -2.525174263 -0.187511936 0.035521373 0.171888876
1552767_a_at -2.898297374 -0.539300859 0.019943706 0.137885059
1552769_at -2.890746987 -0.195058468 0.02017602 0.138393594
1552785_at -2.423187536 -0.684569958 0.04164248 0.180009953
1552790_a_at -2.309971914 -0.644916934 0.049691263 0.191262928
1552791_a_at -1.633605172 -0.559117408 0.140983637 0.292663767
1552792_at -1.292409784 -0.042503788 0.232293022 0.382384451
1552793_at 0.091089124 0.01617933 0.929661261 0.954766451
1552794_a_at -1.15295847 -0.119660572 0.282210872 0.429067376
1552798_a_at -1.295546873 -0.028873242 0.231261376 0.381652552
1552801_at -1.66353723 -0.200983445 0.134775005 0.286149311
1552803_a_at -0.472765529 -0.143672744 0.649009975 0.751627211
1552806_a_at 0.085472664 0.009334757 0.933986022 0.957474363
1552807_a_at 2.055031228 1.205315921 0.073928328 0.21780337
1552808_at -1.313510747 -0.274406673 0.225428556 0.37671417
1552809_at -1.295756381 -0.16042195 0.231192617 0.381640772
1552812_a_at -1.923370943 -0.485358446 0.090643027 0.236473716
1552816_at -1.143423429 -0.163092827 0.285922868 0.432663332
1552822_at 0.727061257 0.261004193 0.487915955 0.617922781
1552825_at -1.354968109 -0.682455642 0.212445571 0.365360796
1552826_at -2.212422181 -0.716611206 0.057862007 0.200987304
1552829_at -2.142446842 -1.269268974 0.064530027 0.208059618
1552835_at -1.861442953 -0.741365008 0.099709383 0.247311092
1552836_at -1.872030944 -0.689728316 0.098100273 0.245416955
1552841_s_at -1.524574971 -0.142076682 0.165872551 0.318792349
1552863_a_at -2.181337343 -1.061680037 0.06073571 0.204507507
1552867_at -0.252454318 -0.030627045 0.807055233 0.869319971
1552876_at -2.035519202 -0.223256954 0.076201887 0.220000924
1552885_a_at -0.139383047 -0.011077145 0.892592533 0.929562612
1552887_at -0.600961513 -0.088354286 0.56450024 0.682227298
1552892_at -1.139021365 -0.123989567 0.287649856 0.434049899
1552895_a_at -1.492856068 -0.216349499 0.173823122 0.327000632
1552897_a_at -1.933609506 -0.454244913 0.089222234 0.234621154
1552899_at -2.223356222 -0.337556274 0.056883512 0.199945427
1552903_at -2.505023611 -0.285106936 0.036654009 0.173593379
1552904_at -1.82454834 -0.10835409 0.105514631 0.254207032
1552908_at 2.975728652 3.009301064 0.017715525 0.131117273
1552921_a_at 0.008900372 0.002633475 0.993116572 0.995815258
1552927_at 1.114575407 0.242144812 0.297393697 0.443920204
1552930_at 2.302232842 0.427715472 0.050295223 0.192173048
1552931_a_at 0.669469134 0.188504896 0.522044794 0.646365972
1552939_at -3.331557969 -0.521196382 0.01036037 0.104545556
1552942_at -2.171490868 -0.475804351 0.061675053 0.205056226
1552943_at -3.259604494 -1.242412168 0.011534111 0.110199588
1552948_at 0.214768653 0.023189027 0.835321336 0.889424231
1552952_at -1.930517091 -0.715901975 0.089649096 0.235109318
1552953_a_at -0.063045337 -0.003528407 0.951277168 0.968442859
1552954_at 1.178731852 0.256485285 0.272372729 0.419245194
1552957_at -3.122166634 -0.081611849 0.014182162 0.119838439
1552961_at -1.107517595 -0.253294122 0.300255464 0.446970272
1552970_s_at -4.386451377 -1.083257471 0.002328581 0.05152694
1552977_a_at 5.190743481 2.289460594 0.000831754 0.030161851
1552978_a_at 1.819214474 0.499536249 0.10637994 0.255132514
1552979_at -2.569444414 -1.102415153 0.033156206 0.168283155
1552980_at 0.902473529 0.088056637 0.39316615 0.533084805
1552985_at -1.387460729 -0.507374151 0.202725706 0.356195105
1553002_at -0.271114348 -0.058783799 0.793167261 0.860090479
1553003_at -1.465156122 -0.417867228 0.181042624 0.334334161
1553004_at -2.854138023 -0.146825323 0.021342845 0.141877582
1553011_at -2.899280553 -0.422833215 0.01991366 0.137885059
1553015_a_at 1.798336673 0.561653259 0.10983185 0.259374179
1553020_at -1.70135772 -0.223868121 0.127291004 0.277832425
1553030_a_at -1.666175739 -0.164719947 0.134239974 0.285435035
1553034_at -3.887116042 -0.640908545 0.004628033 0.071911026
1553037_a_at -1.135261552 -0.222374277 0.289131533 0.435552843
1553042_a_at -1.617541273 -0.16787915 0.144422948 0.296579154
1553053_at -1.737560567 -0.268609233 0.120490225 0.270656966
1553057_at -1.91153471 -0.361606381 0.092312573 0.238521175
1553060_at -2.734141832 -0.877906092 0.025680783 0.152476507
1553074_at -2.083728214 -0.256346274 0.070704207 0.213848502
1553081_at -1.95363994 -0.277480752 0.086504268 0.23123696
1553083_at -2.214337478 -0.77246954 0.05768941 0.200987304
1553088_a_at -2.891939601 -0.708899779 0.02013914 0.138309695
1553096_s_at 0.21515799 0.104001424 0.835027928 0.889250521
1553099_at 3.006909855 0.805555079 0.016892878 0.127706788
1553101_a_at 2.730150537 1.497711037 0.025839782 0.152822416
1553102_a_at 2.125613086 0.774696153 0.066243855 0.209916991
1553103_at -0.38785614 -0.223961964 0.708238638 0.797326912
1553106_at 1.708649362 0.199720487 0.125893174 0.276289655
1553107_s_at 0.049747166 0.024808242 0.961543483 0.975004877
1553108_at 0.162771565 0.011686105 0.874734765 0.917297419
1553111_a_at 0.675634991 0.196787275 0.518321666 0.643201346
1553112_s_at 1.359785684 0.497168647 0.210979456 0.36422868
1553113_s_at 0.280485752 0.135132307 0.786221628 0.854708487
1553118_at 0.567616687 0.155765861 0.585867593 0.699842535
1553123_at -1.320057539 -0.432135243 0.22333424 0.374984994
1553125_x_at -1.746994351 -0.538736381 0.118774581 0.268901072
1553129_at -1.379426329 -0.152347433 0.205092493 0.358393422
1553132_a_at -2.185954829 -0.450389032 0.060300083 0.203601137
1553133_at -1.481112477 -0.358314266 0.176851997 0.329948116
1553137_s_at 2.709736443 0.854767139 0.026668976 0.155072234
1553138_a_at 1.263311922 0.278500788 0.242048959 0.391899726
1553141_at -1.295677162 -0.507802924 0.231218614 0.381640772
1553142_at -1.621766163 -0.297901654 0.14351102 0.295590516
1553147_at -1.529982368 -0.331972094 0.164550167 0.317451383
1553148_a_at -1.61954444 -0.323483601 0.143989912 0.296034056
1553150_at -1.866934859 -0.542013288 0.09887164 0.24628617
1553153_at -2.905223523 -1.79336122 0.019733039 0.13737123
1553155_x_at -1.933341099 -1.31263973 0.089259206 0.234672818
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