Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000134
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue Bone marrow
Cell Line B cell
Platform GPL570
Accession GSE20910
GEO Title Expression data from Down syndrome and Nn-Down syndrome pediatric acute lymphoblastic leukemia cases
PMID 21647151
Article Title GeNmic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles
Author Loudin MG, Wang J, Leung HC, Gurusiddappa S, Meyer J, Condos G, Morrison D, Tsimelzon A, Devidas M, Heerema NA, Carroll AJ, Plon SE, Hunger SP, Basso G, Pession A, Bhojwani D, Carroll WL, Rabin KR
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20910
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/21647151
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE20nnn/GSE20910/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1007_s_at 0.386691492 0.075608813 0.700848487 0.89636932
1053_at 0.037225944 0.006233817 0.970473237 0.991942438
121_at -0.107159378 -0.010081777 0.915149669 0.974934882
1294_at 1.661535466 0.342408405 0.103715808 0.465037584
1316_at -0.52013218 -0.090532263 0.605578781 0.856455828
1405_i_at 1.537256247 0.686471175 0.131391417 0.504467665
1552256_a_at 0.291174857 0.055715313 0.772285832 0.926257184
1552257_a_at -0.765135274 -0.173090229 0.448275702 0.772961375
1552263_at 0.465662587 0.134257849 0.64375389 0.874406395
1552264_a_at -0.013443773 -0.002917889 0.989334518 0.997280111
1552274_at 0.377307248 0.059933005 0.70775911 0.899424345
1552275_s_at 0.42616025 0.10756312 0.672068728 0.885649814
1552277_a_at -2.018387807 -0.601353667 0.049672298 0.354144569
1552283_s_at 2.188767026 0.266054963 0.03396487 0.309251329
1552286_at -0.215912845 -0.042684658 0.830053521 0.947758346
1552287_s_at 3.113603952 0.805221004 0.003245567 0.14065161
1552291_at -0.557075349 -0.128448196 0.580298835 0.843367695
1552295_a_at 0.200916969 0.020100254 0.841689389 0.951508349
1552301_a_at 2.722668143 0.453280161 0.009247444 0.194575826
1552302_at 1.119272155 0.23056166 0.269097151 0.649055189
1552303_a_at 0.300334952 0.038400116 0.765336152 0.923576921
1552307_a_at -0.322374237 -0.062461437 0.74869602 0.917177816
1552309_a_at 0.964485835 0.454061717 0.340073634 0.704502743
1552310_at -0.212208033 -0.053454313 0.832924749 0.948410959
1552314_a_at 0.906207252 0.109564848 0.369762183 0.725913162
1552315_at 1.554055358 0.353322057 0.127335374 0.497903619
1552316_a_at 0.911026793 0.277046649 0.367245496 0.724596475
1552318_at 0.896436776 0.23993057 0.374898099 0.730265394
1552323_s_at 0.086539974 0.019536689 0.931429809 0.979548892
1552327_at 0.90321662 0.090251105 0.371329405 0.726985589
1552329_at 0.664349731 0.196239275 0.509933297 0.808279944
1552330_at 0.000268519 4.92E-05 0.999786967 0.999880897
1552332_at -1.084280586 -0.104533314 0.284146072 0.660315538
1552334_at 0.254343567 0.020036362 0.800415079 0.938797051
1552340_at -1.662271951 -0.122800945 0.103567303 0.464827213
1552344_s_at -0.52349683 -0.105053123 0.60325536 0.855295374
1552347_at 6.242389295 0.799145847 1.49E-07 0.004055087
1552354_at -0.71929114 -0.057642349 0.475764708 0.790043691
1552364_s_at -0.532290948 -0.119328537 0.597202355 0.851659958
1552370_at -0.933507035 -0.124769791 0.355652991 0.715901927
1552375_at 0.288763167 0.033553459 0.774118732 0.927043131
1552383_at -2.191715363 -0.151545158 0.03373691 0.308858747
1552386_at -1.230683602 -0.356773291 0.224979856 0.608790005
1552398_a_at -1.344444632 -0.194160622 0.185695226 0.571042875
1552399_a_at 2.495348008 0.298696006 0.016407225 0.236084967
1552411_at -2.215080062 -0.153524784 0.031977746 0.301499417
1552417_a_at -0.930034911 -0.179198035 0.357427728 0.716797999
1552422_at -0.038718682 -0.009678243 0.969289825 0.99140083
1552423_at 3.120225112 0.562877861 0.003186558 0.140131612
1552426_a_at 2.971142655 0.620025445 0.004793588 0.157108514
1552472_a_at -0.506673474 -0.104120283 0.614913714 0.860354694
1552473_at -2.54314696 -0.237246113 0.01457732 0.228107915
1552474_a_at -2.637777033 -0.394322017 0.011492458 0.210677797
1552481_s_at 0.774203383 0.059486805 0.442950857 0.770491361
1552485_at -0.855420139 -0.102601277 0.396952866 0.744112402
1552486_s_at -2.142044871 -0.410555131 0.037763427 0.322724027
1552496_a_at -1.412720881 -0.260975785 0.164772612 0.546759139
1552497_a_at -1.650089673 -0.150521162 0.106046331 0.46892519
1552515_at -0.224437303 -0.019606273 0.823456039 0.945913269
1552516_a_at 1.331836988 0.175633395 0.189772053 0.576152511
1552536_at 0.088870591 0.006536116 0.929588039 0.979288268
1552541_at 1.247914548 0.207628496 0.218662796 0.602341396
1552542_s_at 0.897141741 0.327714301 0.374526009 0.729945223
1552583_s_at 2.816753492 1.034523256 0.007236489 0.180786428
1552584_at 0.824495586 0.17275996 0.414105425 0.754139172
1552594_at -2.64714619 -0.216184529 0.011222143 0.208784301
1552607_at 2.275889468 0.331388458 0.027774935 0.287390067
1552610_a_at 0.446166697 0.097362399 0.657664858 0.881398686
1552611_a_at -0.821007163 -0.149496935 0.416068399 0.755195673
1552612_at -0.348923949 -0.100282502 0.728810674 0.909229518
1552613_s_at -0.292548315 -0.086822803 0.771242582 0.92597942
1552615_at -1.461257731 -0.119152281 0.151049915 0.530365052
1552617_a_at -0.123589903 -0.018479812 0.902202839 0.971379814
1552618_at 0.535733877 0.072669701 0.594840388 0.850931258
1552619_a_at 1.328520052 0.25361674 0.190855876 0.576650865
1552620_at -0.660847145 -0.052132063 0.512155799 0.809349966
1552621_at 2.831210286 0.575749388 0.006966157 0.179071251
1552622_s_at 2.430803269 0.481967792 0.019209281 0.250252213
1552623_at 4.71061694 1.315926716 2.49E-05 0.026169094
1552625_a_at 0.376815631 0.065555072 0.708121834 0.899516006
1552627_a_at -0.784938939 -0.125812517 0.436695477 0.767259381
1552628_a_at -1.813308682 -0.29196291 0.076608836 0.413985502
1552633_at 1.050626651 0.28147472 0.299166424 0.671751446
1552634_a_at 1.290839179 0.451980463 0.203500943 0.588345714
1552641_s_at 1.846319413 0.252803727 0.07157934 0.405203122
1552643_at 2.85239459 0.556704453 0.006586929 0.17581886
1552644_a_at 1.378815066 0.282218727 0.174921484 0.556690682
1552648_a_at -1.283096158 -0.215593104 0.206175834 0.590563027
1552652_at 2.747502453 0.763371523 0.008671648 0.19120167
1552656_s_at 1.244676111 0.146941163 0.21983988 0.603614657
1552657_a_at -0.458004003 -0.029508162 0.649203517 0.8769539
1552660_a_at 0.272011647 0.025737018 0.786885421 0.932137144
1552664_at 0.012213519 0.002068022 0.990310476 0.997801478
1552665_at -0.221015135 -0.066794845 0.826103095 0.946882052
1552667_a_at 2.038005436 0.435160996 0.047588761 0.348653385
1552669_at 0.894964599 0.069051797 0.375675894 0.730745545
1552670_a_at 1.630144297 0.440320517 0.110210019 0.474967612
1552671_a_at -0.345165969 -0.053808854 0.731614272 0.910300707
1552678_a_at 1.123743308 0.305969124 0.267215758 0.64731783
1552680_a_at 1.26964588 0.276012888 0.210884996 0.595483689
1552682_a_at 1.804659099 0.152551286 0.077974925 0.416703895
1552690_a_at 0.387885271 0.096967093 0.699971198 0.896123285
1552691_at 0.321701899 0.088938335 0.749201909 0.91726258
1552701_a_at 0.933473667 0.414435981 0.355670019 0.715901927
1552703_s_at 1.311231384 0.446206785 0.196581428 0.581950724
1552711_a_at 2.3012516 0.187119745 0.02617274 0.281831645
1552713_a_at 1.058803775 0.551366491 0.295467333 0.669490569
1552714_at 0.858021728 0.352710516 0.39553036 0.743311819
1552716_at 0.546849819 0.087188499 0.587244761 0.846815877
1552717_s_at -0.411494609 -0.038846661 0.682707489 0.889706042
1552719_at 1.164307822 0.144740383 0.250573649 0.633137813
1552724_at 0.650485498 0.050641248 0.518761075 0.813162451
1552729_at 1.318879626 0.258319882 0.194032675 0.579477733
1552733_at 1.380535127 0.263409354 0.17439526 0.556099901
1552734_at 2.74183854 0.243582057 0.008799974 0.191710198
1552735_at 1.407118456 0.327093732 0.16641721 0.548417613
1552736_a_at 2.798324048 0.945742665 0.007595225 0.184070576
1552739_s_at -0.156582777 -0.024510732 0.876289946 0.962791285
1552749_a_at -1.717316422 -0.161031314 0.09295336 0.445764745
1552755_at -0.392611371 -0.07756215 0.696502138 0.894407796
1552760_at -0.371246344 -0.084703619 0.712235717 0.901093846
1552766_at 1.858003593 0.207427812 0.069867501 0.401642521
1552767_a_at 2.062587388 1.142409881 0.045085568 0.341270169
1552772_at -0.573137187 -0.060259503 0.569469544 0.837540836
1552773_at 0.818423145 0.078014754 0.417526111 0.755881986
1552787_at -2.330841264 -0.204517992 0.024408286 0.274615843
1552790_a_at 1.223737976 0.373387817 0.227563989 0.611133007
1552792_at 0.303400973 0.029527803 0.763014317 0.92308134
1552800_at -0.519216629 -0.033701406 0.606211721 0.856658762
1552803_a_at -1.489403158 -0.219072999 0.143514819 0.519509505
1552806_a_at -1.274910616 -0.097093287 0.209032228 0.593659115
1552807_a_at -0.16521898 -0.030907712 0.869528393 0.960309605
1552812_a_at -0.617030771 -0.068065943 0.540394425 0.824127567
1552819_at -1.682870898 -0.117243296 0.099484037 0.458121024
1552822_at 0.239297052 0.035373908 0.811986448 0.942900188
1552828_at -0.086494262 -0.007156573 0.931465937 0.979548892
1552845_at 1.80134508 0.298014366 0.07850374 0.417778819
1552862_at 2.36116321 0.232323691 0.022711503 0.266683445
1552863_a_at -2.165625124 -0.166145234 0.035801949 0.314849607
1552865_a_at -0.5444814 -0.03937624 0.588859226 0.847452627
1552867_at 2.613737418 0.317825494 0.012213601 0.215486866
1552872_at -1.410151018 -0.149176485 0.16552542 0.547270371
1552885_a_at -1.243985402 -0.101161157 0.220091542 0.603903326
1552889_a_at -1.261633227 -0.113612905 0.213728351 0.598141472
1552892_at -1.493674164 -0.227216129 0.142397894 0.517751918
1552899_at -0.496765295 -0.04216023 0.621827588 0.863575633
1552921_a_at 1.564186371 0.316310732 0.124938404 0.494369358
1552924_a_at -1.7246505 -0.302392491 0.091609816 0.443550822
1552927_at 0.195954282 0.029234824 0.845548152 0.952418853
1552928_s_at 0.439464497 0.120926036 0.662475898 0.883236505
1552937_s_at -0.904419711 -0.114750339 0.370698421 0.726497601
1552946_at -0.89719575 -0.152853571 0.374497512 0.729945223
1552947_x_at -1.65112745 -0.243309558 0.105833269 0.468664385
1552977_a_at -0.608969253 -0.115831293 0.545676341 0.827055848
1552978_a_at 0.711211466 0.121017173 0.480706762 0.792425711
1552986_at -0.005656626 -0.000557262 0.995512259 0.99925385
1553015_a_at 1.08953285 0.150867414 0.281850352 0.658563274
1553034_at -0.06029689 -0.00971046 0.952192225 0.985551793
1553042_a_at 1.422231333 0.248997419 0.162009827 0.542183295
1553043_a_at 1.465503264 0.52675437 0.149893721 0.529152935
1553047_at -0.280630653 -0.029890062 0.780309046 0.929993594
1553048_a_at -1.756766473 -0.228152044 0.085915199 0.433241078
1553078_at 0.848370762 0.170725759 0.400823365 0.746400926
1553088_a_at -1.153317407 -0.092670758 0.25500693 0.636608085
1553096_s_at -1.390812985 -0.252967893 0.171276368 0.553031895
1553099_at 2.021419011 0.339704645 0.04934528 0.353190622
1553101_a_at -1.005079416 -0.134547773 0.320354182 0.689270122
1553102_a_at -0.059538964 -0.018485656 0.952792433 0.985602537
1553103_at 3.402182871 0.494869644 0.001433667 0.108101944
1553105_s_at -0.884248899 -0.275409677 0.381368338 0.734111493
1553106_at 0.830517628 0.15019191 0.410730123 0.752004608
1553107_s_at 0.595565978 0.08967597 0.554516431 0.831089832
1553108_at -0.586549319 -0.055647753 0.560503848 0.833678077
1553111_a_at -0.950660594 -0.194034753 0.346969685 0.708327226
1553112_s_at -1.890870848 -0.24549521 0.0652375 0.391781743
1553113_s_at -0.484103394 -0.079838861 0.630713424 0.868159858
1553114_a_at -0.097835164 -0.007976208 0.922507512 0.976707586
1553117_a_at 0.750892591 0.182893764 0.456714562 0.778710449
1553122_s_at 0.458068219 0.07297132 0.649157741 0.8769539
1553132_a_at -0.952205897 -0.148764205 0.346194346 0.707944493
1553133_at 0.609341896 0.154280489 0.545431602 0.826914403
1553134_s_at 0.488491804 0.120895408 0.627627388 0.866309354
1553137_s_at -0.953637387 -0.13262545 0.34547713 0.707692219
1553138_a_at 0.285940666 0.063552617 0.776265506 0.927885737
1553145_at 0.735752597 0.214783651 0.465785535 0.784236023
1553157_at -1.246004901 -0.112533752 0.219356333 0.603129849
1553158_at -0.75012242 -0.172623668 0.45717351 0.779152407
1553162_x_at 0.298573908 0.029953684 0.766670744 0.924060528
1553165_at -0.550665628 -0.07381455 0.584648131 0.845437794
1553168_at -2.2342054 -0.149719923 0.030598801 0.296077558
1553169_at 1.459011194 0.137548966 0.151664557 0.530867764
1553172_at -0.198945519 -0.033856426 0.843221835 0.951770532
1553177_at 0.398423564 0.084563193 0.692244855 0.892549902
1553183_at 0.445136794 0.179618314 0.658403207 0.881398686
1553185_at 0.27395413 0.080768829 0.785401898 0.931470822
1553186_x_at 0.164277717 0.048034261 0.870264869 0.960877138
1553192_at 0.887427907 0.089823541 0.379673883 0.732935671
1553194_at -0.387393035 -0.168276134 0.700332884 0.896202661
1553218_a_at 0.491191811 0.0933822 0.625732014 0.865783551
1553220_at -1.484113942 -0.364161123 0.144907639 0.521553926
1553221_at -1.88952061 -0.135765359 0.065422422 0.391931692
1553224_at 0.69268406 0.118701163 0.492147806 0.798289763
1553225_s_at -0.712610861 -0.099305808 0.479848735 0.791983533
1553227_s_at 2.238626492 0.453426592 0.030287654 0.295053396
1553246_a_at -0.028860378 -0.002478786 0.977106455 0.9934393
1553247_a_at 2.742059931 0.508233394 0.008794925 0.191710198
1553252_a_at -0.824217931 -0.173277863 0.414261457 0.754322709
1553253_at -0.980163965 -0.074269036 0.332364057 0.69827906
1553262_a_at -2.43698442 -0.172058829 0.018923324 0.248696716
1553267_a_at -0.157950677 -0.017651865 0.875218338 0.962503488
1553269_at 0.441801269 0.108344156 0.660796843 0.882628485
1553274_a_at -2.592875044 -0.432708951 0.012872792 0.219690281
1553285_s_at 0.895125806 0.071000744 0.375590673 0.730745545
1553286_at 3.038714058 0.789802548 0.003988674 0.149929855
1553292_s_at 2.818074028 0.604040893 0.007211398 0.180635478
1553297_a_at 0.44086432 0.110765156 0.661469863 0.882670971
1553301_a_at -2.081089006 -0.234746982 0.043278019 0.336205604
1553304_at -0.743109977 -0.137948272 0.461364558 0.781584106
1553313_s_at 1.103750861 0.296290311 0.275701193 0.65440016
1553323_a_at 0.415941416 0.028415054 0.679474664 0.888851899
1553338_at 0.653780131 0.192730097 0.516655907 0.811898558
1553348_a_at 0.952800952 0.142732861 0.345896088 0.707862427
1553349_at 3.430233737 0.887693522 0.001321814 0.106220693
1553359_at -1.195291237 -0.104674445 0.238376008 0.62129549
1553366_s_at -0.125369257 -0.009938274 0.900802302 0.971012311
1553369_at 1.693034386 0.46082963 0.09751883 0.454605224
1553380_at 0.660247215 0.220564822 0.512536998 0.809349966
1553387_at 2.014535893 0.214629822 0.050090568 0.355173473
1553396_a_at -2.00894153 -0.279554796 0.050703483 0.35713767
1553399_a_at -5.541070958 -0.415465393 1.59E-06 0.007223459
1553407_at 1.690647232 0.254379563 0.097977502 0.455072916
1553423_a_at 0.081624593 0.017756402 0.935315422 0.980560036
1553435_at 0.155894621 0.0125503 0.876829133 0.962926555
1553444_a_at -0.388099043 -0.034050565 0.699814145 0.896061041
1553457_at -1.227462527 -0.108946476 0.226175555 0.609902223
1553483_at -2.337359013 -0.304310076 0.024034255 0.272202142
1553510_s_at -0.387995486 -0.067138445 0.699890224 0.896061631
1553526_at -1.941618365 -0.14044805 0.058603684 0.377203877
1553528_a_at -1.230214121 -0.274843671 0.225153841 0.609062138
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