Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000120
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue IPSC
Cell Line IPSC derived neurons
Platform GPL570
Accession GSE48611
GEO Title Gene expression of human isogenic trisomy 21 induced pluripotent stem cells and derived neurons
PMID 23716668
Article Title Deficits in human trisomy 21 IPSC and neurons
Author Weick JP, Held DL, Bonadurer GF 3rd, Doers ME, Liu Y, Maguire C, Clark A, Knackert JA, Molinarolo K, Musser M, Yao L, Yin Y, Lu J, Zhang X, Zhang SC, Bhattacharyya A
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48611
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/23716668
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE48nnn/GSE48611/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1053_at -2.308300182 -0.297855669 0.082185628 0.294084755
117_at -13.16999345 -0.638290625 0.000191999 0.09352736
121_at -3.473100658 -0.301926976 0.025511529 0.201488072
1255_g_at -1.019782423 -0.129931204 0.365491657 0.585299472
1316_at 1.154961525 0.278136123 0.312404661 0.538999482
1438_at -2.624548981 -0.24315854 0.058519529 0.259320717
1552258_at 0.9174453 0.145570688 0.410821386 0.624403463
1552261_at -11.06828566 -0.463476851 0.000378929 0.100821712
1552263_at 0.624621424 0.14917814 0.566080932 0.741203646
1552264_a_at 2.711702526 0.399746311 0.053443111 0.250871167
1552266_at -2.938946718 -0.243146023 0.042433631 0.232492769
1552269_at -0.499501189 -0.074503792 0.643651506 0.795631669
1552272_a_at 1.195364834 0.349419649 0.297967199 0.525940035
1552274_at 2.374916427 0.498218613 0.076410772 0.286249489
1552275_s_at 3.518533448 0.299759508 0.024482439 0.19920068
1552278_a_at -0.550670195 -0.133713695 0.611167771 0.774051352
1552279_a_at -0.09705709 -0.017798068 0.927349687 0.962894918
1552286_at 0.960896091 0.21495236 0.391019137 0.606985837
1552287_s_at 0.072411805 0.023219303 0.945750391 0.972605427
1552288_at 0.333161868 0.060483399 0.755743216 0.867911186
1552289_a_at -0.803125847 -0.121759308 0.466911667 0.668366248
1552291_at -2.867906082 -0.429567534 0.045564666 0.238489545
1552296_at -0.122387058 -0.027103763 0.90849502 0.953945972
1552301_a_at 1.727174154 0.368302338 0.159207945 0.386941069
1552303_a_at 3.020640696 0.377933829 0.039138589 0.227096965
1552306_at 0.672990658 0.128311753 0.537833716 0.72032997
1552307_a_at 4.100882718 0.403938102 0.01484232 0.173575639
1552309_a_at -0.262436376 -0.041881599 0.805946763 0.898362342
1552310_at -0.253233039 -0.042720793 0.812570584 0.901660125
1552312_a_at 2.189493341 0.399447104 0.093745085 0.309649286
1552314_a_at 0.437418141 0.105312075 0.684388685 0.822132131
1552315_at -0.433939132 -0.066553309 0.686712381 0.823831894
1552316_a_at -2.532825613 -0.311156011 0.064470612 0.267665279
1552319_a_at -1.807365808 -0.280389532 0.144990716 0.371434138
1552321_a_at -1.00816037 -0.132208085 0.370411794 0.589255709
1552322_at 0.822282093 0.165803868 0.457106767 0.660620164
1552323_s_at 1.604181877 0.329313265 0.183940874 0.414460873
1552327_at 0.839804965 0.183582185 0.448281294 0.654411602
1552329_at 2.421374077 0.264323457 0.072655018 0.280373488
1552332_at 1.602031177 0.205578847 0.18440741 0.41476236
1552334_at 1.488521546 0.431231647 0.210840448 0.440726425
1552335_at -2.143189386 -0.283420515 0.098733503 0.315841115
1552338_at 0.369068762 0.081896523 0.73078238 0.852173503
1552343_s_at 0.559695052 0.11162978 0.605545599 0.770109829
1552344_s_at 3.272509223 0.469642626 0.030716492 0.211043515
1552347_at 3.171357277 0.668417334 0.033813803 0.217756938
1552349_a_at 0.617251502 0.100248163 0.570472408 0.744630379
1552354_at 0.466433012 0.133064432 0.665175382 0.80952351
1552362_a_at 2.059330203 0.292516355 0.108534964 0.329002635
1552364_s_at 1.469973501 0.236526836 0.215513608 0.445380654
1552365_at 1.438380627 0.358671895 0.223715155 0.453228251
1552367_a_at -1.329765683 -0.225502681 0.254357462 0.484310886
1552368_at -1.202092166 -0.400783612 0.295624771 0.523440994
1552370_at -0.727774375 -0.107685989 0.507065443 0.698372288
1552375_at -0.984232461 -0.173247892 0.380723844 0.598577657
1552378_s_at 10.73227764 0.377201823 0.000427224 0.102609652
1552381_at 0.017573865 0.005084141 0.986820449 0.993222233
1552383_at -0.82371476 -0.112694337 0.456380056 0.660163893
1552384_a_at -1.328943738 -0.202754777 0.254604433 0.48440835
1552389_at 0.835251785 0.200472885 0.450561351 0.655986577
1552390_a_at -0.109132531 -0.02030645 0.918353056 0.958642576
1552393_at 0.912771267 0.127961147 0.413000941 0.626270224
1552395_at -1.715359342 -0.228652793 0.161424549 0.389214899
1552396_at -3.630704731 -0.42944991 0.022146063 0.194261747
1552399_a_at 3.81861976 0.333192388 0.018800533 0.184332986
1552400_a_at -0.943608105 -0.164570157 0.398798874 0.613727522
1552405_at -1.874247663 -0.286913639 0.134170406 0.359892635
1552408_at 0.835853682 0.159430043 0.450259414 0.655931688
1552409_a_at -5.058637402 -0.438408074 0.0071874 0.147734339
1552410_at -4.496620489 -0.472825229 0.010850603 0.162555099
1552411_at -2.454557218 -0.381999535 0.070100593 0.275712723
1552414_at 0.217797355 0.039315406 0.838246411 0.915529639
1552415_a_at -0.345573174 -0.058255812 0.747072471 0.862779601
1552417_a_at 1.656268471 0.818698459 0.173008775 0.402434416
1552419_s_at -0.655519577 -0.124050864 0.547920896 0.728196631
1552422_at -3.153071132 -0.528445804 0.034412287 0.21864103
1552423_at 4.737163008 0.458765211 0.009056114 0.156167167
1552426_a_at -4.236468527 -0.362031502 0.013301046 0.171625103
1552430_at 2.773696772 0.452675134 0.050140839 0.245755353
1552439_s_at -0.610820946 -0.14033606 0.574322827 0.74688897
1552449_a_at 0.049343864 0.010562335 0.963010863 0.98158918
1552450_a_at -2.753211874 -0.248075533 0.051205188 0.247149985
1552453_a_at -1.141816516 -0.146853647 0.317240153 0.542544161
1552455_at 1.067064673 0.269100228 0.346064688 0.568947099
1552456_a_at -2.65485188 -0.375314894 0.056693948 0.256816638
1552463_at -1.289410076 -0.157686413 0.266762527 0.496335348
1552470_a_at 0.805718667 0.354231138 0.46557498 0.667558833
1552473_at -2.276773173 -0.298873408 0.085088961 0.298965168
1552474_a_at -1.240783216 -0.156194567 0.282486583 0.512054602
1552476_s_at 5.34904362 0.337557183 0.00588942 0.145667118
1552477_a_at 0.241726838 0.115032885 0.820878503 0.906676091
1552481_s_at -0.054737035 -0.009507322 0.958972829 0.979895128
1552485_at 4.673033404 0.69788662 0.009496832 0.157929663
1552486_s_at 2.252547671 0.678968735 0.087398261 0.301744458
1552487_a_at 1.104459319 0.293944358 0.331360342 0.555815805
1552494_at -1.530082735 -0.267718141 0.200738957 0.431740546
1552496_a_at 0.929674336 0.276581859 0.405164378 0.619209633
1552497_a_at -6.029875006 -0.417144588 0.003812469 0.139748091
1552498_at -2.281113728 -0.329433949 0.084682476 0.298226958
1552501_a_at -0.840617854 -0.09930795 0.447875203 0.654027924
1552502_s_at 2.027729707 0.561499134 0.112503035 0.334240875
1552506_at -0.146958962 -0.025560598 0.890273899 0.943588807
1552518_s_at 1.964880367 0.367168764 0.120876486 0.343710645
1552535_at 2.814518139 0.42696705 0.04809537 0.242847993
1552538_a_at -1.89008842 -0.231715294 0.131737094 0.357575855
1552540_s_at -1.525841058 -0.221729718 0.201746909 0.432715505
1552542_s_at -0.049345496 -0.010145449 0.96300964 0.98158918
1552543_a_at 1.548187522 0.284443586 0.196494279 0.427153315
1552544_at -2.619933611 -0.28072295 0.058803472 0.259717193
1552546_a_at -1.611816504 -0.400256467 0.1822946 0.41254238
1552548_at 0.312669385 0.075566852 0.770154651 0.876024448
1552553_a_at 0.533811994 0.083634495 0.621756841 0.780440025
1552557_a_at 0.658153873 0.095036897 0.546391518 0.726977868
1552558_a_at -2.932328424 -0.391483454 0.042714488 0.233187599
1552559_a_at -6.510975173 -0.832003525 0.00287197 0.130703348
1552562_at 0.333729306 0.061389833 0.755345831 0.867710276
1552568_at -9.593888058 -0.421367481 0.000659711 0.113326042
1552570_at -0.028518875 -0.005038093 0.978614467 0.988897668
1552572_a_at 2.555585859 0.347959109 0.062931653 0.265350791
1552573_s_at 2.537279292 0.365373047 0.064166114 0.267091449
1552576_at -1.286565938 -0.191317882 0.267658571 0.497080877
1552579_a_at -2.159723471 -0.301752779 0.096919125 0.313524935
1552580_at 0.947326169 0.356803053 0.397114693 0.612299944
1552582_at 2.004519158 0.273873905 0.115519051 0.338088233
1552583_s_at 0.645389279 0.197115124 0.553829952 0.732455302
1552586_at -3.085528068 -0.37138978 0.036733593 0.222447158
1552590_a_at -0.02803842 -0.004670994 0.978974628 0.989066121
1552594_at 3.809937524 0.52175687 0.018941157 0.184721551
1552596_at -3.066157581 -0.267843018 0.037432926 0.223567966
1552604_at -0.149766211 -0.024707798 0.888197152 0.942563889
1552605_s_at -1.081965661 -0.220204866 0.34013619 0.563569477
1552610_a_at 3.228123636 0.494069453 0.032032505 0.214293928
1552611_a_at 1.58275779 0.640795818 0.188643299 0.419709436
1552612_at 2.533966302 0.34077478 0.064392466 0.267422157
1552613_s_at 2.573623483 0.513701246 0.061741855 0.263812296
1552617_a_at 3.037321423 0.292786773 0.038503142 0.226197674
1552619_a_at 3.503966609 0.393619658 0.024806921 0.200348356
1552621_at 1.919943469 0.577580802 0.127279789 0.352270617
1552622_s_at 1.916572777 0.81341156 0.127774746 0.352711001
1552625_a_at 3.038506998 0.671608655 0.03845844 0.226104565
1552627_a_at 3.033842578 0.515570665 0.038634664 0.226540589
1552628_a_at 1.221638904 0.418474113 0.288916708 0.518136652
1552630_a_at 0.861578777 0.244820333 0.437505582 0.645294074
1552632_a_at 0.586556142 0.192617048 0.589007294 0.757259436
1552634_a_at 0.813225416 0.153098553 0.461721912 0.664349653
1552639_at -0.819946217 -0.159856897 0.458293591 0.661482663
1552641_s_at 0.620529204 0.128928362 0.568516512 0.74300751
1552644_a_at 1.278883093 0.382950044 0.270093582 0.499399029
1552648_a_at 2.340906887 0.561987428 0.079299652 0.290315207
1552649_a_at -1.226623367 -0.181367383 0.2872293 0.516493076
1552651_a_at 1.925730896 0.254119986 0.126434799 0.351234183
1552657_a_at -1.953528245 -0.220926406 0.122460329 0.345647271
1552658_a_at -1.21914576 -0.153235462 0.289764238 0.51894158
1552660_a_at 3.229651565 0.700999493 0.03198611 0.214176731
1552664_at -2.339974769 -0.395902375 0.079380548 0.290315207
1552665_at 0.155016642 0.035823837 0.884315913 0.940895041
1552667_a_at 0.328093018 0.068876582 0.759297047 0.869863751
1552670_a_at 2.210031857 0.546541102 0.091622866 0.306750122
1552671_a_at 3.206888576 0.314701938 0.032685589 0.215129456
1552672_a_at -1.863404015 -0.259224917 0.135864047 0.361200327
1552677_a_at 1.684283836 0.315020453 0.167411443 0.396210198
1552678_a_at 3.324790761 0.631275154 0.029247427 0.208402252
1552680_a_at 1.535437118 1.019323127 0.199473937 0.430646985
1552682_a_at 2.821943986 0.309964407 0.047733771 0.242243895
1552684_a_at -0.229269565 -0.052503913 0.829905244 0.911259097
1552685_a_at -0.33181095 -0.096693876 0.756689652 0.868262285
1552689_at 0.47892825 0.077765149 0.656994669 0.804378904
1552691_at 0.311777333 0.046190446 0.770784604 0.876415019
1552693_at 0.888332093 0.131150829 0.424554423 0.634982915
1552695_a_at 1.570130669 0.447966791 0.191472832 0.422372182
1552696_at 0.398010295 0.063028685 0.71095081 0.839489253
1552698_at 0.720223965 0.123809272 0.51122774 0.701486667
1552705_at 0.553537478 0.083323368 0.609378012 0.772752334
1552712_a_at 1.203193896 0.653696903 0.295242806 0.523024528
1552716_at -0.112229198 -0.019635875 0.916048244 0.957568844
1552717_s_at 5.72745398 0.563775417 0.004600692 0.140688705
1552719_at -0.085386164 -0.015994448 0.936057462 0.967338495
1552721_a_at -0.766404307 -0.214579721 0.486164724 0.682273817
1552725_s_at -1.794554353 -0.223896572 0.147168171 0.374266882
1552729_at 0.268833733 0.051521945 0.801353988 0.89539946
1552734_at 2.055856251 0.294949465 0.108963561 0.32965714
1552735_at 1.424384521 0.292505707 0.227447994 0.456797362
1552736_a_at 1.486753761 0.272073434 0.211281385 0.441247132
1552737_s_at 1.131010913 0.211644819 0.321266654 0.546675842
1552739_s_at 1.79900721 0.296625668 0.146407421 0.373416874
1552742_at 0.769333149 0.205789481 0.484607093 0.680658468
1552749_a_at -2.187155062 -0.28772304 0.093990154 0.309925752
1552750_at -0.946540637 -0.143940411 0.397470014 0.612524194
1552751_a_at -4.310048001 -0.434696446 0.012545565 0.1687533
1552754_a_at 0.013733552 0.003752095 0.989700241 0.994727429
1552766_at 5.073003805 0.976991934 0.007115448 0.147476709
1552767_a_at -1.352912179 -0.274503362 0.247498034 0.477576236
1552769_at 0.894886331 0.257569684 0.421430002 0.632455012
1552775_at -5.698664632 -0.300947837 0.004685726 0.140764986
1552777_a_at 0.281736835 0.050839744 0.792120309 0.889413099
1552782_at 0.527720735 0.117892432 0.625610507 0.78295292
1552787_at 4.065654837 0.874264508 0.015277441 0.174998114
1552788_a_at 2.956709632 0.467339472 0.04169043 0.231474706
1552790_a_at 0.842059535 0.163809122 0.447155715 0.653537117
1552792_at 0.257279118 0.085575216 0.809656163 0.900407658
1552794_a_at -1.361532119 -0.190437315 0.244990174 0.474918478
1552796_a_at -1.917552643 -0.245848004 0.127630646 0.35264016
1552797_s_at 1.684375886 0.33263345 0.167393368 0.396210198
1552807_a_at -0.745067844 -0.146444766 0.497627029 0.690843645
1552812_a_at 2.47312575 0.926658987 0.068715849 0.273521133
1552816_at 0.877997638 0.129019754 0.42951959 0.638945075
1552818_a_at -2.680452623 -0.347411791 0.055202614 0.254145163
1552828_at 4.098318233 0.380132653 0.014873488 0.173575639
1552833_at -0.881600893 -0.208627523 0.427783031 0.63761981
1552834_at -3.522288581 -0.284044836 0.024399612 0.198941717
1552839_at -1.631847185 -0.307383272 0.178047647 0.408243267
1552843_at -3.262386623 -0.474594864 0.031010915 0.211916595
1552845_at 0.820726032 0.105103722 0.457897108 0.661202455
1552848_a_at 5.325336526 1.275414875 0.005984015 0.145712427
1552849_at 0.160400823 0.048781982 0.88033988 0.938639623
1552853_at -1.965048076 -0.264799429 0.120853255 0.343680378
1552856_at -0.075430622 -0.017654051 0.943493994 0.971347396
1552857_a_at -1.755651739 -0.259203443 0.1539965 0.381443071
1552865_a_at -5.919316244 -0.513334715 0.004079826 0.139748091
1552867_at 0.037240534 0.016464355 0.972077667 0.986455804
1552872_at -2.295295201 -0.371935886 0.083369542 0.295993853
1552875_a_at -0.104333359 -0.014720794 0.92192693 0.960377781
1552880_at 1.203222302 0.246957005 0.295232964 0.523024528
1552884_at -2.302640478 -0.457538111 0.082698521 0.295020044
1552887_at -2.208835616 -0.379252395 0.091744991 0.306970803
1552890_a_at -1.732026488 -0.210002065 0.158306926 0.386048259
1552892_at -1.462824528 -0.198216235 0.217342595 0.446685641
1552898_a_at 2.924649409 0.344447055 0.043043081 0.233525602
1552903_at -1.758262086 -0.402996859 0.153527935 0.380745558
1552908_at -0.341159722 -0.047763185 0.750150691 0.864768622
1552911_at -0.751080259 -0.127435007 0.494376607 0.688606796
1552914_a_at 1.40580212 0.36211865 0.232500323 0.461284154
1552915_at -0.935200135 -0.184049907 0.40262978 0.616613574
1552919_at 2.103282477 0.531114769 0.103269991 0.322462183
1552921_a_at 2.659512744 0.467663971 0.056419013 0.256250428
1552922_at 0.120589855 0.027487841 0.909830568 0.954476793
1552924_a_at 1.586698213 0.229726045 0.187769171 0.418412354
1552925_at -0.680761067 -0.1541184 0.533389804 0.717316663
1552932_at 0.724190978 0.124087564 0.509037719 0.699958905
1552933_at 1.357613203 0.207036382 0.246127219 0.47600678
1552935_at -1.450669312 -0.331190428 0.220488343 0.449974193
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