Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000119
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue IPSC
Cell Line IPSC derived neurons
Platform GPL570
Accession GSE48611
GEO Title Gene expression of human isogenic trisomy 21 induced pluripotent stem cells and derived neurons
PMID 23716668
Article Title Deficits in human trisomy 21 IPSC and neurons
Author Weick JP, Held DL, Bonadurer GF 3rd, Doers ME, Liu Y, Maguire C, Clark A, Knackert JA, Molinarolo K, Musser M, Yao L, Yin Y, Lu J, Zhang X, Zhang SC, Bhattacharyya A
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48611
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/23716668
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE48nnn/GSE48611/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

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ID Statistic DM P-value P-adj
1007_s_at 3.632872614 0.223739874 0.022103595 0.111981715
1053_at 0.216052154 0.033410299 0.839517596 0.899656524
1316_at 1.867342866 0.243886863 0.135246198 0.287082764
1431_at -0.225976985 -0.029232892 0.832296488 0.894927659
1438_at -5.296339207 -0.590279343 0.006102258 0.066385756
1494_f_at -0.065484929 -0.010826681 0.950930132 0.972185338
1552256_a_at -0.770049986 -0.162453856 0.484226442 0.635258455
1552261_at -1.556803932 -0.198503666 0.194506569 0.358053939
1552263_at 2.659183226 0.389344815 0.0564384 0.17672817
1552264_a_at -3.058586246 -0.303591873 0.037710511 0.144888592
1552269_at 1.507539054 0.575972252 0.206155562 0.370904654
1552272_a_at 2.695750749 0.465033257 0.054333045 0.173366971
1552274_at -0.154634715 -0.025383337 0.884598112 0.929246597
1552275_s_at -2.686371542 -0.694927557 0.054864283 0.17415465
1552277_a_at -0.797093417 -0.134993659 0.470033197 0.623014732
1552280_at 1.867901585 0.286383702 0.135158802 0.286993564
1552283_s_at 8.379799152 0.605521747 0.001109356 0.038896654
1552286_at 9.031762636 0.673697493 0.000832484 0.036723439
1552288_at -1.885393979 -0.503734705 0.132453203 0.283526543
1552289_a_at -1.211258392 -0.224984483 0.292461006 0.461615042
1552291_at 3.171769636 0.603979439 0.033800448 0.13737587
1552293_at -0.514604009 -0.110243013 0.633957991 0.753825854
1552301_a_at 1.030076258 0.23531118 0.361181852 0.52685723
1552303_a_at 0.072572446 0.011670907 0.945630305 0.968398632
1552304_at 0.556297933 0.122803393 0.607658048 0.733671324
1552307_a_at -0.058222917 -0.010387061 0.956363624 0.975913342
1552309_a_at -2.799486353 -0.662821981 0.048837115 0.164629761
1552312_a_at -0.632198284 -0.139708436 0.561590089 0.697625642
1552314_a_at 2.378036666 0.422176799 0.076151744 0.206740854
1552315_at 0.538404966 0.083493395 0.618860721 0.742567598
1552316_a_at 1.047687836 0.179203915 0.353912299 0.519757296
1552320_a_at 1.485593461 0.38124618 0.211571304 0.376718595
1552321_a_at 1.949871032 0.503120591 0.122975385 0.272161093
1552322_at -0.64229798 -0.123396321 0.555641875 0.692843157
1552326_a_at 3.184043842 1.197666555 0.033405781 0.136535004
1552327_at -4.802818004 -0.36887193 0.00863039 0.075387537
1552329_at -2.915817667 -0.585833801 0.043424652 0.155030036
1552330_at 4.698628878 0.643077736 0.009317875 0.077476779
1552338_at 0.611779599 0.116341971 0.573747714 0.707143087
1552344_s_at -3.534943372 -0.469966604 0.02412293 0.117109809
1552347_at 7.853959197 0.700520717 0.001419904 0.040553435
1552348_at -1.437939501 -0.217417407 0.223831864 0.391039851
1552349_a_at -1.982780625 -0.286354968 0.118424259 0.266410678
1552362_a_at -1.322648625 -0.320127139 0.2565037 0.424104756
1552364_s_at -4.179539474 -0.823337197 0.013923481 0.091305136
1552365_at 1.948843441 0.361810325 0.123120528 0.272300964
1552375_at 13.95114927 0.767871651 0.000153102 0.022597826
1552378_s_at -2.720987773 -1.347429466 0.052932851 0.170970478
1552389_at -4.728497692 -2.645951668 0.009114191 0.076836087
1552390_a_at -4.158953597 -2.756787995 0.01415717 0.091800727
1552395_at -0.830199392 -0.141823021 0.453102219 0.608728619
1552396_at 4.275655689 0.251317237 0.012892055 0.088686149
1552400_a_at 3.129249158 0.652825176 0.035210753 0.140360058
1552401_a_at 0.704562998 0.130657431 0.519941154 0.664211142
1552410_at -3.8292567 -1.642197808 0.018629951 0.103543544
1552415_a_at 1.447278565 0.220097674 0.221374003 0.388336022
1552417_a_at -5.928338612 -1.367870259 0.004057162 0.057393918
1552419_s_at 0.79777089 0.127706927 0.469681824 0.622972356
1552422_at 0.658854254 0.158639285 0.545985404 0.685866377
1552425_a_at 1.156765991 0.146623816 0.311746221 0.480590119
1552427_at -8.517613671 -1.318174113 0.001042292 0.038049243
1552438_a_at 1.420795962 0.214186908 0.228415073 0.395880799
1552439_s_at 0.907555998 0.367029246 0.415444261 0.574589525
1552456_a_at -1.22811043 -0.284211644 0.286727691 0.455779854
1552459_a_at 1.049266963 0.21228998 0.353266867 0.519260648
1552461_at 2.794740493 0.347475776 0.04907405 0.164925235
1552463_at -0.844314191 -0.103400161 0.44603236 0.602372008
1552470_a_at 3.381512497 0.802556181 0.027746639 0.125004077
1552478_a_at 0.781837036 0.137994752 0.47800016 0.630148814
1552486_s_at -3.935293655 -0.682544123 0.017027015 0.100073108
1552487_a_at -0.517678626 -0.244173909 0.631995319 0.752376692
1552490_at 1.573130967 0.30548436 0.190796576 0.353840879
1552496_a_at 0.773223072 0.213156072 0.482544236 0.633812311
1552498_at 0.182160572 0.024544464 0.864315876 0.916428177
1552499_a_at 5.379746005 0.455734357 0.005769613 0.065222036
1552506_at -3.256731571 -0.431017486 0.031176846 0.131905015
1552508_at 1.105223304 0.127219839 0.331065913 0.498488328
1552509_a_at 0.163257984 0.022446979 0.878231686 0.925335485
1552519_at 1.133651147 0.160143731 0.320278505 0.488413095
1552521_a_at 0.446300806 0.110016105 0.678474956 0.787387358
1552522_at -0.329705408 -0.050663534 0.758165796 0.844633356
1552523_a_at 0.840021748 0.137817872 0.448172968 0.604241481
1552526_at 0.053418162 0.008180519 0.959960178 0.977501216
1552532_a_at -2.290573399 -0.425753059 0.083804132 0.218042462
1552540_s_at 6.911058805 0.415494877 0.002299649 0.047150736
1552546_a_at -0.442627492 -0.105738907 0.680917148 0.78938285
1552557_a_at 1.25847717 0.285194362 0.276664928 0.445227047
1552562_at 1.420467229 0.184900294 0.228503868 0.395984428
1552563_a_at 0.144696125 0.022057996 0.891948678 0.933805076
1552564_at 0.883858344 0.131140759 0.426698008 0.585086663
1552569_a_at 0.649246498 0.113671873 0.551574828 0.689659319
1552570_at 0.917231095 0.143861325 0.410921061 0.570993612
1552572_a_at -3.273407295 -0.317712611 0.030690531 0.131065944
1552573_s_at -2.739931857 -0.603441265 0.051909161 0.169184955
1552575_a_at -0.729884855 -0.194271407 0.505906502 0.653122893
1552579_a_at 5.115651221 0.550419173 0.00690697 0.068982964
1552580_at -1.14374013 -0.159659535 0.316528247 0.484914739
1552583_s_at 0.007103947 0.001210949 0.994672096 0.996789351
1552586_at 0.502170089 0.077180513 0.641932183 0.759630118
1552590_a_at 0.609043362 0.085025201 0.575390251 0.7085279
1552610_a_at -7.661123908 -1.13755193 0.00156025 0.0418098
1552611_a_at -12.63780072 -0.765096278 0.00022571 0.025444297
1552612_at -11.36181568 -0.383587227 0.000342183 0.028704794
1552616_a_at -0.994387509 -0.119889689 0.376317316 0.53969121
1552617_a_at -2.660347307 -0.426080386 0.056369946 0.176558586
1552619_a_at -11.20417852 -1.348167183 0.000361337 0.02927038
1552621_at -1.26399177 -0.145236872 0.274874084 0.443165681
1552622_s_at -2.187298958 -0.265951673 0.093975052 0.232746186
1552625_a_at -6.577036788 -0.731083863 0.00276628 0.050237007
1552626_a_at 1.646590841 0.849993638 0.174987537 0.335289431
1552627_a_at -0.223137989 -0.054217492 0.834360082 0.89622896
1552628_a_at 5.151443086 0.603317921 0.006737731 0.068419667
1552629_a_at 1.759881927 0.212802749 0.153237931 0.308909646
1552632_a_at 1.222426177 0.668199577 0.288649567 0.457715742
1552633_at 2.151282866 0.291603653 0.097840687 0.238232124
1552634_a_at 1.156036741 0.251378896 0.312012165 0.480780894
1552639_at 1.207200797 0.157361936 0.293857548 0.462936261
1552649_a_at -4.196937344 -0.323033892 0.013729602 0.090709053
1552651_a_at -3.487237356 -0.40451339 0.025185903 0.119272681
1552658_a_at -1.044927654 -0.384683546 0.35504298 0.520750046
1552660_a_at -2.315893684 -0.34499571 0.081503109 0.214777447
1552664_at 3.242719147 0.560054214 0.031592539 0.132796819
1552666_a_at 0.26664687 0.104075379 0.802922895 0.874954728
1552667_a_at 1.121807388 0.386004287 0.324733125 0.492623611
1552676_at -2.244061053 -0.306359769 0.088223809 0.224493461
1552677_a_at 2.744040284 0.347962962 0.051690184 0.16886702
1552678_a_at -4.558308266 -0.908046134 0.010352114 0.081423
1552680_a_at -1.74309294 -0.49855198 0.156272147 0.312791509
1552682_a_at -3.592456932 -0.487354901 0.022911578 0.113775474
1552686_at 1.11500243 0.19001462 0.327318166 0.494755043
1552689_at 2.321274687 0.580007498 0.08102332 0.214202214
1552695_a_at 1.219922001 0.234792794 0.289500107 0.458628767
1552696_at -9.769297503 -0.750863624 0.000615112 0.034208259
1552698_at 5.97454712 0.696057692 0.003943484 0.057145936
1552701_a_at -0.760670553 -0.147016803 0.489225124 0.639512721
1552703_s_at -1.897955607 -0.309002287 0.130546369 0.28143843
1552705_at 5.041703371 0.566082902 0.007273354 0.070452715
1552708_a_at 3.432329625 0.414921804 0.026479051 0.121825941
1552711_a_at 3.484338514 0.372118745 0.025252271 0.119400608
1552712_a_at 2.864756129 0.808815844 0.045709612 0.159344654
1552714_at 3.143186091 1.212970009 0.034741002 0.139382573
1552716_at -1.00627789 -0.23809752 0.371214164 0.535241188
1552717_s_at -5.538005792 -0.818010311 0.005197267 0.062906282
1552725_s_at -0.93432215 -0.17878647 0.403031602 0.56385253
1552726_at -4.052057718 -2.025981593 0.015449485 0.095358172
1552727_s_at -3.894592541 -2.911340514 0.017621928 0.101344608
1552729_at 5.616522944 0.572307931 0.004939155 0.061983301
1552733_at -0.313332673 -0.054185366 0.769686386 0.853034194
1552734_at -0.980235762 -0.191461202 0.382470318 0.545808671
1552735_at 2.719912538 0.379559314 0.05299165 0.17101504
1552736_a_at 1.95799756 0.430540601 0.121834089 0.270801923
1552737_s_at -5.63643007 -0.515118219 0.004876225 0.061615865
1552738_a_at 3.003938723 0.368488391 0.039787186 0.148480099
1552740_at 7.576016472 0.729136516 0.001627627 0.04219816
1552742_at 0.001557148 0.000397769 0.998832139 0.999307896
1552752_a_at -2.759095042 -0.577286595 0.050896857 0.16776222
1552754_a_at -1.577926878 -0.350257492 0.189720702 0.352487819
1552755_at 2.231108272 0.278254388 0.089500702 0.226203829
1552760_at -2.334144965 -0.422940905 0.079888621 0.212376452
1552761_at -1.437022475 -0.181779306 0.224074678 0.391313837
1552766_at -2.23544745 -0.99185223 0.089070653 0.225680917
1552767_a_at 1.764718671 0.505846778 0.152375454 0.307969132
1552770_s_at 0.456767468 0.082552577 0.671542434 0.782161357
1552771_a_at 2.044486303 0.187921836 0.110379404 0.255989468
1552773_at -0.394027743 -0.065413681 0.713663915 0.814380328
1552774_a_at -2.639791978 -0.498141397 0.057592903 0.178570677
1552775_at 0.215060018 0.039533098 0.84024052 0.899961075
1552782_at 3.921396905 0.833243756 0.017227388 0.100761564
1552785_at -1.041000361 -0.234882084 0.356657283 0.522640537
1552787_at 2.588148292 0.337176126 0.060802487 0.183943353
1552789_at 1.640234075 0.272840618 0.176300133 0.336683274
1552790_a_at 1.973814135 0.340443641 0.119645756 0.268106746
1552792_at 1.623395655 0.336146225 0.17982688 0.340523772
1552793_at -3.257886271 -0.932697378 0.03114288 0.131813188
1552794_a_at -0.110965137 -0.019792197 0.91698895 0.950330206
1552798_a_at 0.017741467 0.002390843 0.986694772 0.992656674
1552803_a_at 4.467372911 0.511541887 0.011097094 0.083105328
1552813_at -0.248162038 -0.035701615 0.816228449 0.883670369
1552818_a_at 1.460660629 0.405426935 0.217899284 0.384389034
1552825_at 5.786265296 0.310333046 0.004432785 0.059624469
1552828_at -4.581670433 -0.301439104 0.010170605 0.080723623
1552829_at 0.805809389 0.148852385 0.465528264 0.619298197
1552835_at -6.414679243 -0.673710297 0.003035091 0.051758064
1552836_at 3.073362378 0.373802933 0.037171001 0.144083841
1552839_at 1.560419174 0.175695856 0.193678732 0.35714421
1552843_at 1.896417845 0.328675148 0.130778196 0.28165364
1552845_at 4.156112923 0.478719504 0.014189787 0.091816663
1552848_a_at 1.050509295 0.465634635 0.352759828 0.519012344
1552853_at -0.530143036 -0.076570108 0.624076284 0.746723071
1552860_at -0.766027552 -0.15852421 0.486365369 0.637024788
1552867_at 4.237496875 0.755587727 0.013290115 0.089693493
1552868_at 0.413628221 0.084398817 0.70036134 0.803937563
1552878_at -5.739176898 -5.383288981 0.004566609 0.060222748
1552879_a_at -6.715408747 -5.332016394 0.002559998 0.049193033
1552882_a_at 1.088930095 0.144184412 0.337396817 0.504777073
1552884_at 0.016035322 0.003078835 0.987974152 0.993211921
1552885_a_at 0.621226153 0.080683648 0.568101208 0.702926619
1552887_at 0.404792181 0.055375767 0.706342575 0.808492218
1552892_at 0.103266983 0.023811981 0.922721352 0.953608401
1552903_at 2.911643535 0.256622845 0.043606365 0.1554053
1552911_at 0.500853318 0.069984956 0.642780118 0.760178175
1552914_a_at -4.980856325 -0.669579639 0.007592724 0.071675132
1552919_at -3.310766249 -0.584787331 0.029633191 0.128622465
1552921_a_at -3.084704546 -0.746608464 0.036763011 0.143229239
1552925_at 1.036292791 0.30153921 0.358600889 0.524419231
1552930_at 3.278994152 0.239301857 0.030529609 0.1307867
1552931_a_at -2.346265366 -0.535478216 0.078836404 0.21071915
1552932_at 1.495039322 0.198198771 0.209222771 0.374183716
1552938_at -2.481844988 -0.41187024 0.068076382 0.194873014
1552942_at 0.499139774 0.110888809 0.643884539 0.761055806
1552946_at 0.864392899 0.232152094 0.436128303 0.593457888
1552947_x_at 1.301415861 0.376156199 0.263011954 0.430563814
1552950_at 1.006345735 0.176018817 0.37118522 0.535241188
1552953_a_at 0.471481175 0.121284042 0.661863434 0.774627874
1552954_at 3.914736836 0.75508939 0.017324421 0.100920882
1552955_at -1.720129838 -0.179237735 0.160525647 0.317608385
1552965_a_at -0.312568729 -0.058408091 0.770225722 0.853244764
1552967_at 0.775779276 0.10990049 0.481192327 0.632738019
1552969_a_at -2.966423487 -0.479018947 0.041290436 0.151379785
1552976_at -1.350572374 -0.243787607 0.248183112 0.416262293
1552977_a_at -5.008520571 -0.416509899 0.007445446 0.07112932
1552978_a_at 1.224992015 0.238182637 0.287780537 0.456815216
1552985_at 0.986864523 0.226461155 0.379577457 0.542915523
1552988_at 1.836139587 0.488065491 0.140224944 0.292869995
1552991_at 3.213506433 0.482373899 0.032480386 0.134407755
1553004_at 0.788418453 0.098652627 0.474550582 0.627327565
1553006_at 0.962098314 0.153044627 0.390482975 0.552834973
1553009_s_at -0.79711348 -0.132268392 0.470022788 0.623014732
1553011_at 2.229513721 0.315125515 0.089659319 0.226468817
1553013_at -0.614650156 -0.367772749 0.572027922 0.705915598
1553015_a_at 2.019485653 0.193316068 0.113564275 0.25993763
1553020_at 1.390525159 0.24460241 0.236737471 0.404430091
1553030_a_at -8.484789408 -0.768091258 0.001057799 0.038432211
1553036_at 0.312977697 0.058405209 0.769936975 0.853138784
1553037_a_at 0.964590202 0.208488163 0.389373657 0.551808028
1553042_a_at -0.949298506 -0.130861162 0.396223734 0.557723866
1553044_at -1.349543413 -0.202248486 0.248484973 0.416623522
1553045_at -3.524318573 -0.252926404 0.024354976 0.117539107
1553046_s_at -0.116769062 -0.019407092 0.912671089 0.947524963
1553048_a_at -5.621668979 -0.839575784 0.004922792 0.061916981
1553062_at 3.15202207 0.322685381 0.034446998 0.138692087
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