Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000118
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue IPSC
Cell Line IPSC
Platform GPL570
Accession GSE48611
GEO Title Gene expression of human isogenic trisomy 21 induced pluripotent stem cells and derived neurons
PMID 23716668
Article Title Deficits in human trisomy 21 IPSC and neurons
Author Weick JP, Held DL, Bonadurer GF 3rd, Doers ME, Liu Y, Maguire C, Clark A, Knackert JA, Molinarolo K, Musser M, Yao L, Yin Y, Lu J, Zhang X, Zhang SC, Bhattacharyya A
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48611
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/23716668
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE48nnn/GSE48611/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1053_at 0.414689854 0.072655082 0.699644457 0.902828535
1255_g_at 1.380330617 0.179564186 0.23960749 0.701728016
1294_at 0.547732061 0.079758614 0.613005165 0.868686441
1316_at -1.065950098 -0.190807308 0.346511839 0.746673949
1431_at 0.653509694 0.067552366 0.549089769 0.840457426
1438_at 2.298926214 0.280442904 0.083037071 0.687119641
1552256_a_at 1.207779088 0.255974653 0.293658129 0.720633322
1552257_a_at 0.525983144 0.069488478 0.626712465 0.874606385
1552263_at 4.099087796 0.49950049 0.014864127 0.573534499
1552269_at 1.335557108 0.35550299 0.25262393 0.705784144
1552272_a_at 1.55987943 0.16169205 0.193802095 0.691308684
1552274_at -2.009414608 -0.336915166 0.114875627 0.690020411
1552275_s_at -2.084364936 -0.461494919 0.105500713 0.690020411
1552277_a_at -1.94363375 -0.178761948 0.12385925 0.690020411
1552278_a_at 1.133234529 0.177611288 0.320434245 0.733352041
1552279_a_at 0.091920216 0.011301736 0.931180923 0.979889231
1552280_at 2.024130205 0.259594273 0.112965047 0.690020411
1552281_at 1.880864442 0.282399799 0.133148145 0.690020411
1552283_s_at 3.071715142 0.234394683 0.037230695 0.650040339
1552286_at 0.966492065 0.114367238 0.388528819 0.766062401
1552288_at 2.607512769 0.494327644 0.059575512 0.686601889
1552289_a_at 2.012560278 0.410064758 0.114464255 0.690020411
1552291_at -2.31651856 -0.386149191 0.081447229 0.686691316
1552293_at -2.116976889 -0.420766128 0.10168773 0.690020411
1552295_a_at 1.272800276 0.135015387 0.272036594 0.712959535
1552301_a_at 0.83792723 0.204900171 0.449220471 0.795056727
1552303_a_at -0.013012085 -0.001858716 0.99024128 0.996444656
1552304_at -0.079417947 -0.016001425 0.940514677 0.982167422
1552307_a_at -0.209824143 -0.050528289 0.844058805 0.953968118
1552309_a_at 2.716558274 0.492579614 0.053175563 0.682978331
1552314_a_at 4.424810785 0.29514877 0.011468029 0.548270068
1552315_at -0.04653135 -0.008757122 0.96511722 0.990569036
1552316_a_at 0.115371592 0.01748256 0.913710418 0.974880827
1552320_a_at 0.587963389 0.077416333 0.588148994 0.858456085
1552321_a_at -0.072189817 -0.017012514 0.94591634 0.984286814
1552322_at 1.444653346 0.156535492 0.22206216 0.694732123
1552323_s_at 0.430956832 0.066512668 0.688707653 0.898898292
1552326_a_at 1.631317007 0.653371986 0.178158721 0.690020411
1552329_at 1.163766118 0.194773104 0.30920407 0.728483722
1552330_at -1.877100028 -0.250956057 0.133728694 0.690020411
1552332_at 1.507453132 0.154777763 0.206176489 0.693009773
1552338_at 0.553997714 0.101439946 0.60909104 0.866822182
1552340_at 0.183680832 0.036581047 0.863199181 0.959946112
1552344_s_at -0.367873138 -0.044867457 0.731607306 0.912537415
1552347_at 5.442246139 0.431846953 0.005534798 0.462181026
1552348_at 1.981554779 0.346171398 0.118590448 0.690020411
1552349_a_at 2.065817618 0.352965419 0.107739547 0.690020411
1552354_at -0.389093553 -0.066399009 0.717032429 0.907770264
1552362_a_at 1.746745717 0.319482757 0.155606611 0.690020411
1552364_s_at 0.473266973 0.101558846 0.660694055 0.888512908
1552377_s_at 1.353321794 0.120379349 0.247378293 0.704471682
1552378_s_at 0.929924913 0.392471699 0.405049152 0.77301315
1552381_at -2.256443169 -0.326235603 0.087022224 0.690020411
1552388_at -1.468680705 -0.182951954 0.215843202 0.693383227
1552389_at 1.12967594 0.885879596 0.321767353 0.733989598
1552390_a_at 1.171847779 0.81842507 0.306293107 0.726982342
1552395_at 1.211213959 0.122908293 0.292476265 0.720335248
1552396_at -0.295080685 -0.04673989 0.782614419 0.93227247
1552400_a_at -0.6958719 -0.128816836 0.524823135 0.828754367
1552401_a_at 0.985230418 0.140540405 0.380288835 0.762873508
1552408_at -2.566681183 -0.214424731 0.062196706 0.686601889
1552410_at 1.519560838 0.562014206 0.203248777 0.693009773
1552414_at 0.427994492 0.060231635 0.690692606 0.899903475
1552415_a_at 0.301219205 0.047045714 0.778256695 0.930647912
1552417_a_at -0.624773164 -0.167110227 0.565990756 0.847868312
1552418_at -0.420397772 -0.072798035 0.695796607 0.900940828
1552419_s_at -0.921620416 -0.172885785 0.408882625 0.774536868
1552421_a_at -1.369836851 -0.174610176 0.24259768 0.703428222
1552422_at 0.128842837 0.021271423 0.903700618 0.972037184
1552424_at -0.928935855 -0.165904975 0.405504124 0.773257302
1552425_a_at 1.509133631 0.197433881 0.205767582 0.693009773
1552426_a_at -0.830766794 -0.099533253 0.452816302 0.796449499
1552430_at -2.696930535 -0.588276696 0.054266643 0.684752748
1552436_a_at 3.065879787 0.294593214 0.037443068 0.650040339
1552438_a_at 0.126249776 0.017275054 0.90562578 0.972776799
1552439_s_at -0.668247359 -0.154256801 0.540559287 0.835863406
1552440_at -2.734356145 -0.183166084 0.052208062 0.677491801
1552448_a_at -0.794956927 -0.089291154 0.471142634 0.804063798
1552455_at 0.160921582 0.116643249 0.879955541 0.964053362
1552456_a_at -0.220141037 -0.036441697 0.83654024 0.950553077
1552457_a_at -1.116834662 -0.140326095 0.326620301 0.735525488
1552459_a_at 1.037547796 0.118906048 0.358081823 0.752389755
1552463_at -0.060854861 -0.009661941 0.954394033 0.987371504
1552468_a_at 2.088071347 0.21640945 0.105059499 0.690020411
1552470_a_at 0.72267877 0.172367973 0.509871727 0.821239229
1552476_s_at 1.167217558 0.173253473 0.30795775 0.728198953
1552478_a_at 1.525980736 0.182828209 0.201713635 0.693009773
1552486_s_at -2.36719841 -0.288492478 0.07705578 0.686691316
1552487_a_at 1.431649643 0.970546131 0.225502631 0.695307268
1552489_s_at -0.093018906 -0.014013137 0.930361293 0.979580685
1552490_at 0.660310327 0.137043171 0.545141781 0.838344305
1552496_a_at 0.05432574 0.013929305 0.959280727 0.988951685
1552497_a_at -0.886519822 -0.100320392 0.425421698 0.783418901
1552499_a_at -1.735352016 -0.286673985 0.157692532 0.690020411
1552502_s_at 1.314038853 0.124378292 0.259123675 0.708950701
1552504_a_at -0.996559034 -0.138177336 0.375380802 0.760463562
1552506_at 1.308847039 0.172071819 0.260716115 0.709357736
1552509_a_at 1.254619956 0.187005834 0.277924175 0.715943164
1552510_at 0.728448959 0.087883774 0.50669479 0.820425493
1552511_a_at 1.843853433 0.352427112 0.138976062 0.690020411
1552514_at 2.456790692 0.212034823 0.069932363 0.686691316
1552516_a_at -0.146128102 -0.017240954 0.890888759 0.967491586
1552518_s_at 0.340200046 0.049431019 0.750820777 0.920152243
1552519_at -0.117942145 -0.018851196 0.911798805 0.974346022
1552520_at -3.460689126 -0.410683813 0.025801549 0.634669104
1552521_a_at -1.618614548 -0.45094575 0.180841586 0.690020411
1552532_a_at 1.889019182 0.555144788 0.131899831 0.690020411
1552535_at 5.134017932 0.46294016 0.006819485 0.473066456
1552541_at 0.224195532 0.038631647 0.833591191 0.949526158
1552542_s_at -1.247353803 -0.268503809 0.280311217 0.716422556
1552543_a_at 0.428222491 0.126794286 0.690539725 0.899898498
1552546_a_at -1.427728617 -0.534897632 0.226550478 0.69564857
1552548_at -3.587137607 -0.18485892 0.023020524 0.634669104
1552552_s_at 0.224034823 0.031317168 0.83370802 0.949540405
1552555_at 0.06649444 0.008850448 0.950175055 0.985770519
1552557_a_at -0.550283663 -0.147994756 0.611409296 0.867915009
1552562_at -0.409609735 -0.077723698 0.70307829 0.903423959
1552564_at -0.688444255 -0.097674203 0.529021589 0.830481823
1552566_at -0.449934755 -0.057915694 0.676063622 0.894274639
1552569_a_at 0.298897013 0.065642159 0.779904067 0.930949534
1552572_a_at 0.079910028 0.008797926 0.940147076 0.982108424
1552573_s_at 0.646638638 0.105365083 0.553098816 0.8423736
1552575_a_at -0.275335521 -0.049199432 0.796696169 0.93703593
1552576_at -3.965347088 -0.377665169 0.016603171 0.581280254
1552578_a_at 0.014621426 0.003638766 0.989034419 0.996111457
1552580_at -1.223537125 -0.127675692 0.288272993 0.7202909
1552582_at 0.071745544 0.013139498 0.946248468 0.984365169
1552583_s_at -1.545430698 -0.219090608 0.197134638 0.692252885
1552586_at 0.235918324 0.031017201 0.825083381 0.946938506
1552587_at -0.557105245 -0.1036228 0.607155612 0.866051233
1552594_at -0.835141704 -0.131366429 0.45061659 0.795946477
1552598_at -1.398741795 -0.1845048 0.234449099 0.699004005
1552599_at -0.888863656 -0.146245088 0.424300316 0.783163964
1552607_at -1.176003583 -0.151918859 0.304806165 0.725951779
1552613_s_at -0.925759173 -0.142161122 0.406968324 0.773420918
1552616_a_at -0.624115023 -0.080394405 0.566381944 0.847909244
1552619_a_at -0.03511358 -0.004648352 0.973671577 0.991953003
1552620_at 0.753299843 0.092892188 0.493180712 0.81410746
1552626_a_at -0.303851821 -0.098250709 0.776390809 0.929910864
1552627_a_at -0.850823562 -0.187390995 0.442801861 0.792715247
1552630_a_at -0.751098279 -0.088610351 0.49436689 0.814577739
1552631_a_at 1.292910471 0.201739127 0.265663705 0.711226119
1552632_a_at 0.778652187 0.554047853 0.479676395 0.808253392
1552633_at -0.847468064 -0.130268401 0.444464784 0.793545561
1552634_a_at 0.860976358 0.1932596 0.437800875 0.790490689
1552637_at -0.082489813 -0.012713915 0.938220188 0.98145962
1552639_at 0.298489297 0.053845766 0.780193446 0.931093034
1552643_at -0.60789174 -0.13283214 0.576082495 0.85310557
1552644_a_at -0.891466571 -0.175308264 0.423057835 0.782627056
1552649_a_at 1.685724564 0.130113867 0.167128776 0.690020411
1552651_a_at 0.580263788 0.06343082 0.592855052 0.860275062
1552657_a_at -0.485918388 -0.055998633 0.652443276 0.88483362
1552658_a_at -2.176463831 -0.547935888 0.095119809 0.690020411
1552660_a_at -0.181610975 -0.025952469 0.864719673 0.960580749
1552663_a_at -0.335439173 -0.040913313 0.75414894 0.921418898
1552664_at 0.536911558 0.091038594 0.619801484 0.871243789
1552665_at -0.083414285 -0.009176366 0.937529807 0.981162122
1552666_a_at -2.255557302 -0.650555448 0.087107578 0.690020411
1552667_a_at -0.221212779 -0.075716412 0.835760387 0.950366741
1552670_a_at 0.640487724 0.076981981 0.556704828 0.843905077
1552672_a_at -0.449216174 -0.054643551 0.676540071 0.894683431
1552677_a_at 2.809674001 0.178537911 0.048332967 0.675424772
1552678_a_at 0.814673447 0.128458927 0.460981559 0.798446248
1552680_a_at -2.666638498 -0.422382065 0.056001643 0.686601889
1552682_a_at -1.930396364 -0.180839264 0.125758054 0.690020411
1552685_a_at -3.636877183 -0.292148928 0.022025402 0.625833116
1552686_at -0.18902614 -0.026270481 0.859275914 0.958809819
1552687_a_at 0.818730426 0.082796133 0.458912279 0.797998954
1552690_a_at 0.023419756 0.003496758 0.982437189 0.994478631
1552693_at -0.150872294 -0.026068968 0.88737919 0.966350466
1552694_at -0.305143287 -0.037104712 0.775476139 0.929798513
1552698_at 0.745311978 0.124637383 0.497494733 0.816283571
1552701_a_at 1.371868927 0.307789036 0.24201578 0.702884959
1552703_s_at 1.907980835 0.287553708 0.129045865 0.690020411
1552708_a_at 0.527431128 0.075967574 0.62579409 0.874124542
1552712_a_at -3.065256725 -0.687211269 0.037465828 0.650040339
1552716_at 1.399772598 0.434214407 0.23416357 0.699004005
1552717_s_at -2.783427297 -0.472347575 0.049644254 0.677287532
1552718_at 1.489779451 0.166613757 0.210527258 0.693009773
1552721_a_at 0.235371596 0.036290106 0.825479535 0.946992541
1552725_s_at -1.072648803 -0.118287268 0.343832198 0.744897018
1552726_at 1.514344007 0.803085283 0.204505009 0.693009773
1552727_s_at 1.314414287 1.015653487 0.259008889 0.708950701
1552729_at 0.797190102 0.094810567 0.469983039 0.803806507
1552734_at -0.084681809 -0.016016283 0.936583348 0.981112129
1552738_a_at 0.189408439 0.036902992 0.858995507 0.958782112
1552740_at -0.172472994 -0.023061304 0.871440691 0.961796449
1552742_at -2.287757321 -0.659195704 0.084064534 0.688846817
1552750_at 2.224226854 0.17987799 0.090187482 0.690020411
1552752_a_at 0.585322368 0.089620708 0.58976046 0.85899928
1552754_a_at 0.975203395 0.250507557 0.384679185 0.765763076
1552758_at 0.055638597 0.007934847 0.958297943 0.988951685
1552760_at 0.237622686 0.051486299 0.823848821 0.946409095
1552761_at -0.756823142 -0.093593957 0.491286877 0.813719628
1552763_at -0.630122706 -0.076629348 0.562817875 0.846691911
1552765_x_at 4.15123923 0.286092414 0.014245959 0.573534499
1552766_at -2.134260075 -0.714319508 0.099729033 0.690020411
1552767_a_at -1.550444239 -0.582604376 0.195971674 0.691836646
1552768_at 0.912072401 0.088784275 0.413327658 0.77704861
1552769_at 0.737381681 0.141933543 0.50180564 0.817999212
1552770_s_at 0.461885651 0.102201186 0.668166697 0.891563713
1552773_at -1.2979362 -0.136584742 0.264093707 0.710359197
1552774_a_at -0.120817442 -0.027749099 0.909661422 0.973819532
1552775_at 2.315130327 0.296531136 0.081571432 0.686691316
1552782_at -1.344193423 -0.330364743 0.250060287 0.705644116
1552785_at -1.088565916 -0.2100895 0.337539567 0.741742612
1552787_at 1.865749658 0.336438474 0.135495743 0.690020411
1552789_at -1.664356906 -0.250707197 0.171372898 0.690020411
1552790_a_at -1.794508061 -0.215853105 0.147176102 0.690020411
1552791_a_at 0.533889118 0.074733403 0.621708142 0.872321514
1552792_at 0.433139002 0.062791432 0.687247397 0.898066144
1552794_a_at -1.273224395 -0.251085084 0.271900684 0.712959535
1552797_s_at -0.014105468 -0.002545022 0.989421338 0.996129186
1552798_a_at 1.217375293 0.144570236 0.290367525 0.720327237
1552809_at -1.303951319 -0.152218942 0.262226438 0.709788742
1552811_at 2.66519147 0.432718334 0.05608611 0.686601889
1552812_a_at -1.203894102 -0.210586938 0.29500029 0.720899775
1552816_at -0.816921977 -0.132639996 0.459833779 0.798084607
1552818_a_at 0.961951891 0.183845029 0.390548243 0.766385242
1552822_at 0.630825644 0.076862201 0.562401854 0.846558255
1552827_s_at 2.50725735 0.272552492 0.066251008 0.686601889
1552835_at 1.883730239 0.281254706 0.132708005 0.690020411
1552836_at 0.008819863 0.001352906 0.99338521 0.99725649
1552843_at -2.774332828 -0.190451096 0.050108203 0.677287532
1552845_at 1.724360394 0.237591458 0.159732908 0.690020411
1552846_s_at 0.439634922 0.050247093 0.682910252 0.896500569
1552848_a_at -1.64465265 -0.882693619 0.175386666 0.690020411
1552853_at 1.884704907 0.27975592 0.132558671 0.690020411
1552854_a_at 1.806290812 0.166925915 0.145172094 0.690020411
1552857_a_at -0.406989204 -0.064057399 0.70485296 0.904110703
1552860_at -0.27866852 -0.05001209 0.794312388 0.936264097
1552862_at 2.350788648 0.222318086 0.078447737 0.686691316
1552863_a_at 0.701154814 0.117641594 0.521851663 0.826862345
1552867_at 0.180618753 0.047775775 0.865448799 0.960710975
1552868_at 0.72964077 0.103351532 0.506040437 0.820347909
1552872_at 0.954520524 0.175016732 0.393873009 0.768151604
1552877_s_at 1.89321676 0.200507513 0.131262209 0.690020411
1552878_at 0.974496702 0.848479427 0.384990253 0.765773882
1552879_a_at 1.02647615 0.787270828 0.362684022 0.754398672
1552880_at 2.757194358 0.442072688 0.050996234 0.677287532
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