Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000117
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue IPSC
Cell Line IPSC
Platform GPL570
Accession GSE48611
GEO Title Gene expression of human isogenic trisomy 21 induced pluripotent stem cells and derived neurons
PMID 23716668
Article Title Deficits in human trisomy 21 IPSC and neurons
Author Weick JP, Held DL, Bonadurer GF 3rd, Doers ME, Liu Y, Maguire C, Clark A, Knackert JA, Molinarolo K, Musser M, Yao L, Yin Y, Lu J, Zhang X, Zhang SC, Bhattacharyya A
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48611
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/23716668
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE48nnn/GSE48611/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

<
ID Statistic DM P-value P-adj
1255_g_at -5.612001078 -0.431071342 0.004953587 0.11294271
1316_at 4.76206012 0.858845169 0.008891734 0.12452276
1552264_a_at 2.141397721 0.294321512 0.098932368 0.279002964
1552269_at 0.437906644 0.06590822 0.684062741 0.819902433
1552272_a_at 0.723453021 0.210040351 0.509444588 0.691636948
1552274_at 3.044009583 0.781485681 0.038251759 0.188063112
1552276_a_at 0.795965598 0.11556719 0.470618597 0.659878747
1552278_a_at -1.535336773 -0.259329793 0.199497569 0.40234537
1552279_a_at 0.004511896 0.000779714 0.996616092 0.998464398
1552280_at 0.123445438 0.01721892 0.907708681 0.951849244
1552283_s_at 1.318831015 0.285187669 0.257662211 0.464649606
1552286_at 1.378698716 0.27412131 0.240070097 0.446823943
1552287_s_at -0.243431596 -0.076592742 0.819645773 0.903270945
1552288_at -3.760928758 -0.54448535 0.019758984 0.153314839
1552289_a_at -4.523186255 -0.541156828 0.010632441 0.130602529
1552291_at -1.682132438 -0.223693296 0.167834475 0.365523597
1552296_at -0.819141165 -0.239713139 0.45870319 0.650228382
1552301_a_at 2.37418858 0.354289884 0.076471337 0.248482754
1552304_at -2.22879555 -0.240805093 0.089730862 0.26783306
1552307_a_at 3.407883504 0.355348556 0.027080066 0.168117944
1552309_a_at -1.387198267 -0.323469292 0.237670313 0.444173948
1552312_a_at 0.464471386 0.090277516 0.666464848 0.807959915
1552315_at -3.315144654 -0.225283114 0.029512114 0.173414632
1552321_a_at -2.776947726 -0.237959815 0.049974293 0.209551296
1552322_at 0.874660334 0.218631086 0.431133121 0.627272106
1552323_s_at 2.17661275 0.449925993 0.09510397 0.274105419
1552329_at 1.022641228 0.136906869 0.364290221 0.569035455
1552334_at 1.9366457 0.486277152 0.12485772 0.314169268
1552335_at -3.777408222 -0.315769067 0.019479352 0.152473612
1552337_s_at 1.404545437 0.181691058 0.232846008 0.439095467
1552338_at 0.901532727 0.118554885 0.41828108 0.616467661
1552343_s_at -0.035489239 -0.005687829 0.973390053 0.987098892
1552344_s_at 3.345628582 0.403734057 0.028685171 0.17177133
1552347_at 3.261543539 0.571317774 0.031035586 0.176076817
1552354_at 0.022778001 0.004556954 0.982918345 0.991902095
1552355_s_at 1.985414227 0.273684407 0.118068079 0.304809204
1552364_s_at 0.980517246 0.232787117 0.382347089 0.584240046
1552365_at -0.004788162 -0.000834261 0.996408896 0.998346652
1552367_a_at -1.999040087 -0.185446252 0.116243868 0.302444502
1552368_at -0.526321445 -0.186250682 0.626497827 0.781112719
1552370_at -1.69947182 -0.248000431 0.164456704 0.36108092
1552378_s_at 12.75494649 0.617327379 0.000217694 0.074943538
1552384_a_at 0.289144471 0.0397647 0.786837722 0.883954715
1552389_at -2.071640999 -0.3262359 0.107031016 0.29033224
1552390_a_at -3.507372651 -0.346330659 0.024730594 0.164103688
1552391_at -0.296142232 -0.071865401 0.781860132 0.881262808
1552393_at 0.893182232 0.128720789 0.422240519 0.619582223
1552394_a_at -0.183307127 -0.032931076 0.863473647 0.928158541
1552396_at -4.980397438 -0.384663772 0.007595197 0.1202984
1552398_a_at 1.044898972 0.124385417 0.355054746 0.560347063
1552399_a_at 7.984239731 0.422735213 0.001333863 0.096519173
1552410_at -1.771160923 -0.226563905 0.151234693 0.34551661
1552414_at 1.663208492 0.315417695 0.171604174 0.369690223
1552417_a_at 2.508464436 0.983009632 0.066165702 0.234182848
1552418_at -0.03636677 -0.00692854 0.972732435 0.98682433
1552422_at -4.627444882 -0.648157364 0.009826029 0.128071378
1552423_at 4.116076751 0.613316084 0.014659265 0.141696853
1552426_a_at -3.336314778 -0.546691774 0.028934884 0.172571162
1552427_at -2.352322167 -0.824589686 0.07831646 0.250994655
1552430_at 1.239002216 0.332827357 0.283078994 0.49006245
1552436_a_at 2.293516247 0.214655003 0.083532977 0.258347658
1552439_s_at -0.398792372 -0.10246204 0.710418628 0.837630772
1552449_a_at -0.765478869 -0.150608424 0.486657689 0.673372434
1552450_a_at -1.017739244 -0.134792819 0.366352452 0.570819974
1552455_at -1.024088369 -0.225936855 0.363683374 0.568584521
1552457_a_at -4.654987998 -0.489627788 0.009625513 0.127394494
1552461_at -0.270449955 -0.034229836 0.800195199 0.892206211
1552467_at 2.240478212 0.240073417 0.088574955 0.266394942
1552470_a_at -0.044085281 -0.017534962 0.96694942 0.98378596
1552476_s_at 4.933697529 0.352747403 0.007852058 0.121321121
1552477_a_at -0.24146296 -0.095339705 0.821069372 0.904037108
1552481_s_at 1.600837595 0.302499787 0.184666855 0.385071641
1552482_at 0.194126792 0.027507379 0.855536791 0.923663119
1552484_at -1.772997071 -0.215306436 0.150911223 0.345210845
1552485_at 6.319260179 0.551429894 0.003208117 0.105046932
1552486_s_at 1.66764478 0.489465347 0.170712564 0.369050531
1552493_s_at -1.041005092 -0.16512972 0.356655334 0.56180159
1552496_a_at 1.352872269 0.339298103 0.247509704 0.454277339
1552497_a_at 1.524157356 0.171142237 0.202148439 0.404979111
1552502_s_at 2.691514708 0.615902009 0.054572236 0.2164342
1552506_at -2.744598002 -0.338019606 0.05166054 0.211916485
1552507_at -0.763589121 -0.119264436 0.487665507 0.674194286
1552511_a_at -1.439989352 -0.164294382 0.223290048 0.429195978
1552520_at 2.969304331 0.270281641 0.041172673 0.193481687
1552523_a_at -1.740188639 -0.310741045 0.156803464 0.351764326
1552526_at -0.977708834 -0.108175231 0.383578097 0.585333402
1552531_a_at -1.560528972 -0.196018887 0.193653647 0.395267842
1552532_a_at -1.632065678 -0.226455081 0.178001893 0.376638489
1552535_at 3.1528176 0.5589443 0.034420672 0.182515127
1552542_s_at 1.131295454 0.196834482 0.321160025 0.527310307
1552543_a_at 2.610907781 0.265463778 0.059363339 0.223029076
1552546_a_at -1.763215454 -0.361544156 0.15264295 0.34725222
1552557_a_at -2.416582905 -0.374990679 0.073032506 0.244026618
1552559_a_at -3.053637109 -0.428128851 0.037893265 0.187470022
1552563_a_at 1.61956298 0.293057009 0.180639826 0.379656989
1552573_s_at 1.193491399 0.166558438 0.298622618 0.504840837
1552576_at 0.479881969 0.072599737 0.65637262 0.801238802
1552580_at -0.341779609 -0.126987926 0.749718001 0.862406293
1552582_at 1.482605395 0.198331925 0.212319777 0.41673403
1552583_s_at 1.034517869 0.278983498 0.359336128 0.564461389
1552587_at 1.218584251 0.169146699 0.289955443 0.496676704
1552594_at 3.290280772 0.418690318 0.030207545 0.174347871
1552598_at 1.501242621 0.259773809 0.207694841 0.411289164
1552607_at -2.254617841 -0.25389905 0.087198199 0.263920227
1552609_s_at 0.107527223 0.022707323 0.919548251 0.958109839
1552610_a_at 3.60096203 0.855795036 0.022738658 0.160274085
1552611_a_at 2.016061572 0.658784566 0.114008274 0.299366279
1552612_at 0.773385574 0.117486833 0.482458206 0.669785133
1552613_s_at 1.511464627 0.241625409 0.205201759 0.408642467
1552617_a_at 3.597707519 0.355790814 0.022804642 0.160569321
1552619_a_at 3.527320019 0.398215647 0.024289156 0.163469631
1552621_at 3.345237012 0.84071782 0.028695617 0.171796214
1552622_s_at 3.235878093 1.310897216 0.031797861 0.177100827
1552625_a_at 3.484755137 0.79903236 0.02524272 0.16480649
1552627_a_at 10.68253364 0.952767276 0.00043501 0.07619511
1552628_a_at 1.122709319 0.363980002 0.324391908 0.530664117
1552630_a_at 0.648542505 0.119149421 0.551985942 0.725226601
1552632_a_at 0.160893536 0.043556301 0.879976239 0.936642675
1552634_a_at 0.092261976 0.019057065 0.930925957 0.964334756
1552637_at 1.331132483 0.146739588 0.253947297 0.460841689
1552639_at 1.041916694 0.227376873 0.356280045 0.561500084
1552641_s_at 0.209150093 0.028461766 0.844550738 0.917696514
1552643_at -0.853734866 -0.165743412 0.441363138 0.635990539
1552644_a_at 0.665455826 0.182581956 0.542167894 0.717512553
1552648_a_at 2.855588185 0.653886998 0.04613454 0.202271958
1552649_a_at 0.239506488 0.032398693 0.822485001 0.904720248
1552652_at -4.558679901 -0.35939208 0.010349196 0.12993632
1552658_a_at -1.809333704 -0.3276635 0.144659311 0.338770768
1552660_a_at 4.863249496 0.978848769 0.008259867 0.122246037
1552662_a_at 0.664683002 0.075648233 0.542613825 0.717797965
1552663_a_at 1.934279806 0.2322573 0.125197745 0.314647917
1552664_at -3.548872808 -0.526018043 0.023822686 0.163091889
1552665_at 0.88454075 0.171311231 0.426370461 0.623325399
1552669_at -0.821189805 -0.136409809 0.457661439 0.649657924
1552670_a_at 3.245816914 0.588144279 0.03150008 0.176899202
1552671_a_at 3.192924589 0.244028407 0.033123611 0.1794219
1552673_at 3.165515203 0.316184255 0.034003665 0.181485046
1552676_at -1.933415426 -0.234001934 0.125322224 0.314764747
1552677_a_at 6.288887545 0.624518129 0.003265724 0.105046932
1552678_a_at 4.760825101 0.949039055 0.008899802 0.124560736
1552680_a_at 2.1933889 1.514599773 0.093338383 0.271878577
1552682_a_at 1.286384508 0.221860179 0.267715829 0.47524694
1552685_a_at 0.747250775 0.174309865 0.496445043 0.681303698
1552687_a_at -3.803674514 -0.212126563 0.01904338 0.151162368
1552691_at 1.127415501 0.155382748 0.322616793 0.52912332
1552695_a_at 0.937456169 0.277627083 0.401598826 0.601176335
1552696_at 0.100968936 0.014832179 0.924433705 0.960853669
1552705_at 0.696689045 0.111557202 0.524362718 0.7043609
1552712_a_at 1.366299955 0.745168642 0.24361379 0.450482252
1552713_a_at 0.176804735 0.02618763 0.868253 0.930658152
1552714_at 0.462965619 0.064257742 0.667455602 0.808407304
1552717_s_at 5.653285604 0.577058544 0.004823708 0.112262393
1552718_at 2.109437807 0.191455128 0.102555453 0.283829517
1552719_at 0.329315289 0.054077336 0.758439436 0.867396014
1552721_a_at -1.521904869 -0.531745511 0.202686889 0.405527711
1552724_at 0.251469719 0.040220406 0.81384187 0.900290314
1552726_at -0.209094804 -0.04428481 0.844591093 0.917696514
1552727_s_at -5.504623379 -0.713554887 0.005311995 0.114578027
1552729_at -0.206888279 -0.044952137 0.846202075 0.918414637
1552734_at 1.252696946 0.143430596 0.278554017 0.485610141
1552735_at 2.297019488 0.419266598 0.083211473 0.257937619
1552736_a_at -0.229218597 -0.032825076 0.829942242 0.908932053
1552737_s_at 0.924567971 0.21831863 0.407518518 0.606877217
1552738_a_at -1.659357616 -0.272328127 0.172382079 0.370367624
1552739_s_at 2.255137863 0.235390065 0.087148024 0.263850088
1552740_at -2.098577062 -0.268659338 0.103819932 0.285553712
1552742_at 0.869517942 0.16442281 0.433629072 0.629619037
1552747_a_at -1.485567238 -0.146967394 0.211577861 0.415757947
1552749_a_at -0.587229755 -0.092813999 0.588596346 0.752903007
1552751_a_at -1.625708575 -0.287587095 0.179338129 0.378118057
1552754_a_at -0.936661328 -0.223982448 0.401961795 0.601495943
1552761_at -1.090411259 -0.129573621 0.336816796 0.543083521
1552763_at -0.257116349 -0.042319431 0.809773336 0.897834937
1552765_x_at 0.758852896 0.118368592 0.490198351 0.676130534
1552766_at 3.797215402 0.990360279 0.019149497 0.151477092
1552767_a_at -3.395847594 -0.675546686 0.027381911 0.168816994
1552769_at 1.010624979 0.118151236 0.369363595 0.573457024
1552771_a_at -0.335043335 -0.044377186 0.754425948 0.865197604
1552774_a_at 4.534131908 0.40006425 0.010544102 0.130475401
1552782_at 1.332612757 0.171746317 0.253503808 0.460312207
1552787_at 3.565213737 0.7725507 0.023476115 0.16205267
1552788_a_at 3.569237427 0.397681256 0.023391701 0.162008781
1552789_at -1.489311127 -0.273435764 0.210643806 0.414816079
1552790_a_at -0.238295447 -0.053164335 0.823361674 0.905283426
1552791_a_at -0.978844939 -0.118705148 0.383079698 0.584822653
1552792_at -0.148532883 -0.03118764 0.889109411 0.942152935
1552794_a_at -2.10166996 -0.387696183 0.103458089 0.285125814
1552797_s_at -1.781958173 -0.976830532 0.149343104 0.343265058
1552803_a_at -5.460819983 -0.424626703 0.005467279 0.114744696
1552804_a_at 2.192397951 0.263812526 0.093441652 0.271910029
1552806_a_at -1.521359707 -0.153006022 0.202817429 0.405600338
1552807_a_at -0.356825135 -0.085502067 0.739250536 0.8565022
1552812_a_at 4.004121581 1.289158531 0.016074907 0.144376516
1552816_at -1.018856598 -0.150296134 0.365881488 0.570382457
1552818_a_at -2.453802806 -0.255834031 0.070157521 0.240225399
1552822_at -0.572364903 -0.079445474 0.597708168 0.760177887
1552828_at 2.851531962 0.301347245 0.046324008 0.202744569
1552834_at -5.571374643 -0.29764355 0.005085602 0.114065253
1552836_at 5.515128216 0.34677146 0.005275561 0.114578027
1552841_s_at 0.652740876 0.149104471 0.549537344 0.723408703
1552842_at -0.611817545 -0.104434934 0.573724958 0.741065927
1552843_at -1.947868268 -0.243585897 0.12325844 0.312303513
1552845_at 1.5737877 0.190410708 0.190648879 0.392018165
1552848_a_at 7.662068389 1.117316926 0.001559522 0.097224435
1552849_at 0.312009471 0.10009223 0.770620651 0.874550829
1552862_at 4.407451432 0.329117414 0.011623618 0.133012404
1552863_a_at 2.723780206 0.371545515 0.052780498 0.213198858
1552867_at -0.219235529 -0.094967043 0.837199311 0.913363074
1552876_at -1.109947195 -0.135551684 0.329250677 0.535404895
1552879_a_at -1.388620034 -0.129674831 0.237271212 0.443610251
1552882_a_at -3.484552751 -0.267774507 0.025247359 0.16480649
1552884_at -3.350079495 -0.441133163 0.028566738 0.171634721
1552892_at 0.631503681 0.100511051 0.56200077 0.732750467
1552895_a_at -0.216731308 -0.04001922 0.839022837 0.914512118
1552897_a_at -2.640366057 -0.670733681 0.057558336 0.220371272
1552898_a_at 2.959673495 0.373407277 0.041567907 0.194199687
1552903_at -0.969740138 -0.189723609 0.387089608 0.588126429
1552904_at -0.314072744 -0.035073479 0.769164055 0.87384205
1552908_at -1.609362527 -0.158976158 0.182822085 0.382434464
1552911_at -0.352814096 -0.050245284 0.742034553 0.857832155
1552914_a_at 2.65097312 0.286501003 0.056923925 0.219493469
1552919_at 1.199902568 0.269571378 0.296385273 0.502886567
1552921_a_at 2.098555128 0.34957567 0.103822503 0.285553712
1552925_at -0.830885404 -0.103629899 0.452756552 0.645212794
1552927_at -1.232357277 -0.223194326 0.285299736 0.492408482
1552928_s_at -1.643688403 -0.31804773 0.175585586 0.373738483
1552929_at -1.394652552 -0.18213328 0.235585216 0.441971527
1552931_a_at 2.061038694 0.285820653 0.108324862 0.291967098
1552932_at -0.524592013 -0.077166723 0.627595553 0.781851448
1552942_at 0.144918537 0.020102256 0.891784035 0.943693027
1552952_at 1.796619034 0.175481055 0.146814907 0.340634535
1552953_a_at -3.031176282 -0.316529123 0.038735823 0.188979879
1552954_at -4.453461116 -0.963365869 0.011216717 0.131599305
1552961_at -0.127761231 -0.019901278 0.904503536 0.950555361
1552967_at 2.561666302 0.25314498 0.062527664 0.22728706
1552969_a_at 1.951057227 0.249725514 0.122808072 0.31165605
1552976_at 3.501704755 0.327649696 0.024857763 0.164389941
1552977_a_at -2.007085599 -0.36299473 0.115181245 0.300756045
1552978_a_at 8.13724833 1.523003556 0.001240889 0.094499036
1552979_at 0.394407776 0.073179224 0.713404797 0.839773737
1552980_at -2.073865386 -0.279718022 0.106761733 0.289900146
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