Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000087
Karyotype Trisomy 21
Type DNA microarray
Diseases Down syndrome
Organism Homo sapiens
Tissue Bone marrow
Cell Line B cell
Platform GPL570
Accession GSE110064
GEO Title Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Cells
PMID 29789608
Article Title Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells
Author MacLean GA, McEldoon J, Huang J, Allred J, Canver MC, Orkin SH
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110064
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/29789608
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE110nnn/GSE110064/
SRA Run Selector -
SRP -

Differentially Expressed Genes

The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.

ID Statistic DM P-value P-adj
1053_at -4.878713494 -0.7016166 0.039538567 0.491316427
1294_at 0.734312219 0.34101302 0.53918027 0.88406256
1316_at -2.481332845 -0.462478139 0.131200714 0.594263026
1320_at 1.628581239 0.330062813 0.244948366 0.68990406
1405_i_at 1.807545163 1.177933041 0.212413165 0.662182718
1552263_at -1.532570767 -1.054561746 0.265084918 0.709235448
1552264_a_at 0.292591967 0.080556839 0.797397014 0.959110337
1552274_at -2.429777936 -0.591787581 0.135732781 0.598766235
1552275_s_at -2.435088719 -1.135423112 0.135255943 0.598173886
1552276_a_at -1.348783756 -0.509898131 0.309831515 0.746103684
1552277_a_at -2.654307347 -0.720133801 0.1174515 0.57909214
1552278_a_at -0.552097525 -0.300949143 0.63633787 0.920921377
1552286_at -1.829120761 -1.512168757 0.20888287 0.659241292
1552288_at 0.616599191 0.377171755 0.600334444 0.909545155
1552289_a_at 0.442831159 0.180248381 0.701178273 0.936120942
1552291_at -0.944409355 -0.351369061 0.444648478 0.838974823
1552296_at 0.378699018 0.119541663 0.741332864 0.946317004
1552299_at 0.432232291 1.032214924 0.707712516 0.937897443
1552301_a_at 0.426294973 0.148203214 0.711390935 0.938641823
1552302_at 1.353069362 0.835544014 0.308685752 0.745267297
1552303_a_at -0.172689619 -0.131960397 0.878790325 0.976409856
1552304_at -0.43303818 -0.366758121 0.707214229 0.937744335
1552306_at -0.119066899 -0.094840394 0.916103811 0.986195497
1552307_a_at -1.011516945 -0.337468487 0.418242318 0.824839074
1552310_at -1.786102707 -0.758376178 0.21600023 0.665577012
1552311_a_at 1.320337054 0.3902742 0.317570051 0.752946442
1552312_a_at -0.315326089 -0.466509756 0.782374817 0.956180689
1552314_a_at -1.290355254 -0.41629417 0.325982276 0.758956132
1552315_at -1.356909828 -0.712507817 0.307663408 0.744698047
1552316_a_at -0.837590767 -0.593452827 0.490405526 0.863095966
1552318_at -1.606119692 -1.945863849 0.249478456 0.69452141
1552329_at -5.778068142 -1.542408639 0.028670712 0.477329245
1552330_at -0.331269997 -0.636249567 0.771930267 0.954612709
1552334_at -7.34597919 -0.738476505 0.018031384 0.465336645
1552340_at 1.470506065 0.549385098 0.279231937 0.722241855
1552343_s_at -0.507120074 -0.18561534 0.662457399 0.926816417
1552344_s_at -1.916663412 -1.315679782 0.195332339 0.646960581
1552347_at -0.093102834 -0.139539861 0.934308556 0.988387286
1552354_at 0.927718573 0.34525371 0.451491961 0.842279121
1552360_a_at 0.193411148 0.259679316 0.864498996 0.973318725
1552362_a_at 0.12844449 0.073044398 0.909548332 0.984490119
1552364_s_at 1.52074624 1.28855369 0.267709025 0.711448467
1552368_at 3.358732221 0.651657923 0.078365657 0.537174485
1552370_at -0.892853036 -0.898272919 0.466149979 0.852095799
1552372_at -0.572958 -0.329702334 0.624504183 0.91682745
1552375_at 4.732552651 0.668861236 0.041864889 0.492999547
1552377_s_at -0.974318576 -1.170304286 0.432662159 0.832381949
1552378_s_at -0.592443403 -0.527896751 0.613613849 0.913234699
1552381_at 0.766607734 1.461265696 0.523440327 0.879056476
1552386_at 0.472852103 0.27970817 0.682898676 0.931579036
1552399_a_at -0.14679429 -0.162473729 0.896755465 0.980986767
1552400_a_at -0.813954691 -1.725363601 0.501168801 0.868277094
1552410_at 3.780311182 0.909388009 0.063393912 0.527397585
1552415_a_at 1.242417508 0.348807773 0.339998171 0.76980164
1552417_a_at -0.984638913 -0.787269804 0.428607781 0.830533751
1552421_a_at 1 0.231380618 0.422649731 0.82697585
1552423_at -0.684978346 -1.056503834 0.564087705 0.895008332
1552450_a_at 1.680964775 0.443896981 0.234789295 0.68189284
1552452_at 2.122259851 0.447986571 0.167836372 0.625230781
1552458_at 1.815966935 0.645131594 0.211025832 0.660810937
1552467_at -0.137726131 -0.057484585 0.903071481 0.982642683
1552470_a_at 12.18747219 2.372451422 0.006665209 0.429371492
1552473_at 1.322538483 0.302586757 0.316962827 0.752511932
1552474_a_at 1.204078845 0.417541115 0.351727501 0.778644503
1552476_s_at 1.849285111 1.078539409 0.205653434 0.655552525
1552478_a_at 6.657686089 0.877716957 0.02182488 0.469642602
1552481_s_at -2.342959211 -1.717982415 0.143870352 0.606815544
1552482_at -0.359037895 -0.118319611 0.753928214 0.948739479
1552485_at -1.879433342 -2.577535215 0.200947608 0.650744236
1552486_s_at -0.976073714 -0.571542142 0.431969714 0.832020873
1552490_at -1.203836742 -1.495305144 0.351803079 0.778644503
1552491_at 0.684893104 0.322852161 0.564131645 0.895008332
1552497_a_at -0.472581243 -0.558156914 0.683062068 0.931643574
1552498_at -0.371797841 -0.238805752 0.745739273 0.947415893
1552499_a_at 0.089012065 0.044171193 0.937183269 0.988953945
1552508_at 4.073888208 0.411961243 0.055302558 0.517532047
1552511_a_at -0.523929994 -0.299671927 0.65259982 0.924446552
1552521_a_at 2.041997635 0.467702738 0.177906341 0.633714669
1552535_at 1.982187733 0.347637018 0.1859491 0.639728628
1552536_at -1.46196869 -1.755064951 0.28125173 0.724446726
1552541_at 0.200119448 0.085569888 0.859890002 0.972777045
1552542_s_at 0.226007186 0.17393128 0.842191269 0.96979018
1552546_a_at 5.694982682 1.258352068 0.029476484 0.480732004
1552554_a_at 0.800971216 0.447073533 0.507181401 0.871309805
1552562_at -2.563727771 -0.833054263 0.124385202 0.587351403
1552564_at 2.538912777 0.703394625 0.126384693 0.59022754
1552568_at 0.723219956 0.21660057 0.544689441 0.885520132
1552582_at 6.475533309 0.71240978 0.023027304 0.46995889
1552592_at 0.961527158 0.396731308 0.437745186 0.836137161
1552594_at 5.215520776 0.483628243 0.034851962 0.486241734
1552607_at 1.241612258 1.68930361 0.340239705 0.76980164
1552611_a_at -4.521099773 -0.685041402 0.045602387 0.498706864
1552612_at -0.173330403 -0.089131322 0.878347208 0.976275038
1552613_s_at 0.022628988 0.014912809 0.984000937 0.997517433
1552615_at 0.015166068 0.008896481 0.989276587 0.998945725
1552618_at -0.168384298 -0.125503629 0.881769427 0.977770395
1552619_a_at -1.278373252 -0.905378757 0.329419404 0.761887201
1552621_at 0.453042024 0.275530204 0.694922723 0.93455504
1552622_s_at -0.537297681 -0.32219699 0.644842006 0.923397763
1552625_a_at 0.41081793 0.189842796 0.721039634 0.941390328
1552627_a_at -0.1931799 -0.173581946 0.864658036 0.973318725
1552628_a_at -0.845339431 -0.864375762 0.486928012 0.86204377
1552632_a_at 5.344006619 0.620180381 0.033277929 0.483535072
1552634_a_at 5.482074378 1.173305439 0.031700658 0.482309658
1552637_at -0.555440639 -1.076834277 0.634429311 0.920325741
1552641_s_at -0.08160406 -0.03430403 0.942393041 0.989711522
1552643_at -1.437886452 -0.8816214 0.287048677 0.72882239
1552646_at 1.726961006 0.844239811 0.226316235 0.673410576
1552648_a_at -0.463059312 -0.323425927 0.688823896 0.933399465
1552651_a_at -0.474996157 -0.355709383 0.681606307 0.931114692
1552652_at -0.61731961 -0.747838394 0.599942184 0.909491737
1552656_s_at -15.44791774 -0.630904474 0.004164287 0.429371492
1552657_a_at 1.616961266 0.343751573 0.24727855 0.692177149
1552658_a_at -0.031179166 -0.009976307 0.977958357 0.996459976
1552660_a_at -0.215500337 -0.240673568 0.849357192 0.970739233
1552663_a_at 1.537053402 1.048159461 0.264098673 0.709029676
1552664_at 1.190014825 1.080553071 0.35614979 0.7822163
1552665_at 0.619034699 0.427879415 0.599009219 0.908999986
1552667_a_at -1.134634341 -0.520017476 0.374208049 0.79647284
1552677_a_at -1.566223856 -1.2970986 0.257793592 0.702806692
1552678_a_at -4.452485985 -2.68461587 0.046920558 0.501570096
1552682_a_at 0.103419242 0.073311235 0.927066309 0.987449868
1552687_a_at 2.057848332 0.482332034 0.175853919 0.631676567
1552689_at 0.915907775 0.753140937 0.456402202 0.846339015
1552691_at -12.70708002 -1.207418353 0.006136161 0.429371492
1552693_at -0.785860788 -0.438990108 0.514268944 0.875439879
1552694_at 0.197977757 0.406497224 0.861360495 0.972782781
1552695_a_at 0.154428941 0.248821178 0.891447528 0.979722413
1552696_at -0.264867426 -0.408205573 0.815911294 0.964010276
1552701_a_at 0.580150562 0.287501729 0.620465828 0.91558362
1552708_a_at -0.650078501 -0.247220039 0.582338193 0.902451535
1552711_a_at -0.522777188 -0.265368373 0.653272222 0.924501234
1552712_a_at 0.850961133 1.523778214 0.484420758 0.860396511
1552714_at 7.779717633 0.468421558 0.016123846 0.46144449
1552721_a_at 6.123171082 0.750622565 0.025649754 0.472104284
1552724_at 1.174671987 0.36350175 0.361048897 0.786420082
1552725_s_at 13.65696059 0.56960334 0.005318831 0.429371492
1552731_at 3.138219329 0.512452782 0.088297675 0.547019459
1552737_s_at 0.933943665 0.988402443 0.44892653 0.840757473
1552738_a_at -1.006188055 -1.080902088 0.420275306 0.825433255
1552739_s_at -1.907032601 -0.979680668 0.196764616 0.647336776
1552747_a_at -1.938882157 -0.662027155 0.192080817 0.644660619
1552750_at -0.026298787 -0.013651395 0.981407164 0.997132913
1552754_a_at 5.276250535 0.567433664 0.034094611 0.485109551
1552755_at -4.192607801 -2.084585106 0.052453531 0.51026789
1552757_s_at -1.280517305 -0.817658992 0.328801169 0.76152688
1552761_at 2.187811976 0.986917956 0.16017966 0.618805464
1552766_at 2.123403205 0.694085569 0.167698588 0.625230781
1552768_at 1.555423328 0.41857513 0.260105472 0.705230581
1552769_at 1.090084743 0.742628051 0.389505564 0.805768948
1552772_at 0.431703664 0.171355931 0.7080395 0.938006252
1552787_at -2.388471646 -1.314477653 0.139522547 0.603379196
1552788_a_at -1.021173632 -0.777299252 0.414585866 0.82314891
1552789_at 0.717972158 0.973727594 0.547314252 0.887144552
1552790_a_at 5.062390894 1.749254498 0.036875319 0.490173698
1552792_at -0.31349771 -0.343396369 0.783577421 0.956304865
1552796_a_at 0.443270639 0.231385161 0.70090823 0.936120942
1552797_s_at -4.887432671 -1.523011877 0.039405841 0.491316427
1552798_a_at -1.576471148 -0.345014323 0.255624358 0.700265153
1552799_at 0.854381571 0.320744814 0.482901707 0.859922413
1552803_a_at -0.30858715 -0.235569483 0.786812176 0.957174982
1552804_a_at 0.231381549 0.230905281 0.838535366 0.968853043
1552806_a_at -0.787761984 -0.497709991 0.513371855 0.875008633
1552807_a_at -0.188481981 -0.115149052 0.867891255 0.97460143
1552812_a_at -0.20455381 -0.17627954 0.85684831 0.972273962
1552818_a_at 0.025232246 0.009707798 0.982160947 0.997132913
1552822_at -0.286455226 -0.355244944 0.801477158 0.960504732
1552827_s_at 3.02332797 0.695226032 0.094199228 0.555414972
1552829_at -2.17460488 -1.028578356 0.161683305 0.620128313
1552835_at 0.393701008 0.131846335 0.731809839 0.944218943
1552836_at 0.287955674 0.137644671 0.80047859 0.960373526
1552837_at 4.991641994 0.456526302 0.037868977 0.490657343
1552839_at 1.089288767 0.388212591 0.389785315 0.805768948
1552841_s_at 3.98282326 0.422204388 0.057643391 0.523198577
1552842_at 5.269022682 0.523068776 0.03418347 0.485109551
1552849_at 0.314867755 0.247771512 0.78267619 0.956187914
1552853_at 3.567477963 0.435954966 0.070379602 0.534797104
1552862_at -2.563587566 -0.948999849 0.124396374 0.587351403
1552863_a_at 2.86130818 0.467194204 0.103521905 0.567131941
1552867_at 1.292380448 0.47616056 0.325405619 0.75840951
1552872_at 4.467940583 0.865006952 0.046618829 0.500734756
1552875_a_at -6.660627982 -1.740702022 0.02180623 0.469642602
1552876_at -0.677826466 -0.165709741 0.567785198 0.896588233
1552879_a_at 0.423839889 0.240674581 0.712915716 0.939067851
1552882_a_at 1.859188085 0.579529482 0.204091669 0.653409205
1552887_at 1.013890465 0.253167842 0.417340305 0.824389298
1552898_a_at 3.207681291 0.607993258 0.084983207 0.543407771
1552906_at 8.137555191 0.519865028 0.01476754 0.457971418
1552911_at 3.102118363 0.568808086 0.090093723 0.549082974
1552921_a_at 0.027996596 0.038410285 0.980207295 0.997034803
1552927_at -0.598877627 -0.678519406 0.610052687 0.91272472
1552928_s_at 3.15823039 0.975930426 0.087324107 0.545917872
1552930_at 0.776973562 0.198523039 0.51848283 0.877397878
1552931_a_at -2.763391608 -0.564976503 0.109802171 0.573148464
1552932_at 0.409079596 0.12921407 0.722128707 0.94157418
1552938_at 4.115912961 0.458702839 0.0542688 0.514907376
1552942_at 4.030344378 0.510859038 0.056404234 0.51965853
1552946_at 6.31285984 0.399500749 0.02418609 0.470550669
1552947_x_at -3.402281852 -0.405697623 0.076595423 0.535647527
1552954_at -2.454906251 -0.851608661 0.133497029 0.595535021
1552970_s_at -0.269586104 -0.476850142 0.812745733 0.963190768
1552971_at 0.198680068 0.08343721 0.860878184 0.972777045
1552975_x_at 0.591381366 0.212466707 0.614203327 0.913283906
1552976_at 1.672306969 0.364048682 0.236430156 0.682706926
1552978_a_at 1.740025153 1.493517771 0.223982729 0.671922426
1552980_at -0.260479578 -0.220395594 0.818860066 0.964985134
1552988_at 1.335565442 1.590172975 0.313398395 0.748613194
1552995_at 1.893896848 0.426123024 0.198740855 0.648210437
1552999_a_at 5.89460248 0.586958452 0.027594319 0.477329245
1553002_at 1.912763996 0.658880019 0.195910568 0.647173238
1553011_at 0.539756509 0.194596295 0.643422943 0.922602619
1553015_a_at 0.777340783 0.241277363 0.518308046 0.877210828
1553021_s_at -1.554359299 -0.391543605 0.260334659 0.705236705
1553027_a_at 0.20336932 0.096941953 0.857660402 0.972486958
1553030_a_at -0.223608538 -0.339419447 0.843825052 0.969877575
1553032_at 6.890212594 0.509115705 0.020420719 0.469180444
1553034_at -1.239293823 -1.387165012 0.340936259 0.770113827
1553039_a_at 0.655605757 0.22860764 0.579413039 0.901464382
1553041_at 2.543557775 0.556236894 0.126007013 0.589725648
1553044_at 1.152587294 0.309263386 0.368239714 0.791825091
1553045_at 2.121817753 0.644297946 0.16788969 0.625230781
1553046_s_at 6.173530148 0.617798679 0.025248648 0.47105783
1553047_at 3.806610742 0.676263621 0.062601221 0.527350646
1553048_a_at -1.888005213 -1.039569889 0.199635844 0.648433015
1553055_a_at -0.360705575 -0.364232443 0.752854908 0.948739479
1553058_at 2.214916777 0.835070361 0.157153198 0.617894628
1553060_at 0.255948481 0.122189855 0.821910241 0.965164756
1553062_at 4.214815878 1.0301863 0.051944435 0.51026789
1553066_at 4.459500917 0.617647384 0.046783248 0.500734756
1553069_at 0.689934034 0.819301462 0.561538503 0.893920554
1553071_a_at -0.259047704 -0.090598123 0.819823393 0.965041565
1553075_a_at 1.874974294 0.48701561 0.201634526 0.651411238
1553078_at 0.258440871 0.071195691 0.820231811 0.965134817
1553081_at 1.188389566 0.411374895 0.356665041 0.782570962
1553082_at 1.438298608 0.331102766 0.286948215 0.728739578
1553083_at 0.672245376 0.337621677 0.570685833 0.897460382
1553088_a_at 5.59545896 0.630166259 0.030486484 0.482309658
1553089_a_at 2.351004934 0.539796628 0.143088217 0.60645342
1553093_a_at 2.990036139 0.73210568 0.096014422 0.558693503
1553096_s_at -2.296809942 -1.255978492 0.148472782 0.610388102
1553099_at -0.846839576 -1.421338187 0.486257664 0.861338791
1553101_a_at 1.113666089 0.98206728 0.381320691 0.800395326
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