>>> Option 1: Click the button below to Download all the analysis
>>> Option 2: View all the result online
Basic Information
The table below details the source and basic information of this item.
| Title | Content |
|---|---|
| iBAD ID | iBAD_0000062 |
| Karyotype | Trisomy 21 |
| Type | RNA-Seq |
| Diseases | Down syndrome |
| Organism | Homo sapiens |
| Tissue | Blood |
| Cell Line | Circulating endothelial progenitor cells |
| Platform | GPL9442 |
| Accession | GSE27443 |
| GEO Title | RNA-Seq of rRNA depleted circulating endothelial progenitor cells (cEPCs) in trisomy 21 and euploid samples |
| PMID | 21533138 |
| Article Title | Massive-scale RNA-Seq analysis of non ribosomal transcriptome in human trisomy 21 |
| Author | Costa V, Angelini C, D'Apice L, Mutarelli M, Casamassimi A, Sommese L, Gallo MA, Aprile M, Esposito R, Leone L, Donizetti A, Crispi S, Rienzo M, Sarubbi B, Calabrò R, Picardi M, Salvatore P, Infante T, De Berardinis P, Napoli C, Ciccodicola A |
| GEO Link | https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27443 |
| Pub Link | https://www.ncbi.nlm.nih.gov/pubmed/21533138 |
| FTP Download | ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE27nnn/GSE27443/ |
| SRA Run Selector | - |
| SRP | - |
Differentially Expressed Genes
The gene expression matrix, up- and down-regulated gene list are provided. Click the three following options to download the corresponding list.
GO enrichment
The result of Gene Ontology (GO) enrichment analysis from up- (goup) or down-regulated (godown) genes is shown as follows. Select the option that you’d like to display. The result that failed to enrich wouldn’t be displayed.
KEGG Enrichment
The result of KEGG enrichment analysis from up- (goup) or down-regulated (godown) genes is shown as follows. Select the option that you’d like to display. The result that failed to enrich wouldn’t be displayed.
Interaction network
The network analysis was performed by STRING with up- and down- regulated genes. Select the option that you’d like to display. The different cluster was colored with different colors.
Genome Browser
You can browse the expression pattern of this item as follows, or click “Full-screen view” to display the patterns of all items stored in BDdb. By this, you are allowed to compare different groups observed by different sequencing approaches.