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Basic Information
The table below details the source and basic information of this item.
| Title | Content |
|---|---|
| iBAD ID | iBAD_0000051 |
| Karyotype | Trisomy 21 |
| Type | DNA methylation |
| Diseases | Down syndrome |
| Organism | Mus musculus |
| Tissue | Brain |
| Cell Line | Cerebral cortex |
| Platform | GPL13112 |
| Accession | GSE74505 |
| GEO Title | Trans-effects of sub-chromosomal duplications on DNA methylation patterns in mouse models of Down syndrome: whole genome bisulfite sequencing of cerebral samples from Dp(10)1Yey and Dp(16)1Yey mouse models |
| PMID | 26607552 |
| Article Title | Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models |
| Author | Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stanier P, Temkin A, Yale A, Liu MM, Li Y, Salas M, Kerkel K, Capone G, Silverman W, Yu YE, Moore G, Wegiel J, Tycko B |
| GEO Link | https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE74505 |
| Pub Link | https://www.ncbi.nlm.nih.gov/pubmed/26607552 |
| FTP Download | - |
| SRA Run Selector | https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA300573 |
| SRP | SRP065509 |
Bed Download
The methylation information with BED format was performed by Bismark and was provided here. Click the options to download the corresponding list.
Differential Methylation
The differential methylation was produced by methylKit, an R package. There would be no result if the experiment design cannot meet the requirement of methylKit.
Genome Browser
You can browse the expression pattern of this item as follows, or click “Full-screen view” to display the patterns of all items stored in BDdb. By this, you are allowed to compare different groups observed by different sequencing approaches.