Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000051
Karyotype Trisomy 21
Type DNA methylation
Diseases Down syndrome
Organism Mus musculus
Tissue Brain
Cell Line Cerebral cortex
Platform GPL13112
Accession GSE74505
GEO Title Trans-effects of sub-chromosomal duplications on DNA methylation patterns in mouse models of Down syndrome: whole genome bisulfite sequencing of cerebral samples from Dp(10)1Yey and Dp(16)1Yey mouse models
PMID 26607552
Article Title Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models
Author Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stanier P, Temkin A, Yale A, Liu MM, Li Y, Salas M, Kerkel K, Capone G, Silverman W, Yu YE, Moore G, Wegiel J, Tycko B
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE74505
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/26607552
FTP Download -
SRA Run Selector https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA300573
SRP SRP065509

Bed Download

The methylation information with BED format was performed by Bismark and was provided here. Click the options to download the corresponding list.

Differential Methylation

The differential methylation was produced by methylKit, an R package. There would be no result if the experiment design cannot meet the requirement of methylKit.

Genome Browser

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