Detailed Information

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Basic Information

The table below details the source and basic information of this item.

Title Content
iBAD ID iBAD_0000050
Karyotype Trisomy 21
Type DNA methylation
Diseases Down syndrome
Organism Homo sapiens
Tissue Brain
Cell Line Cerebral cortex
Platform GPL11154
Accession GSE57359
GEO Title Genome-wide profiling of the DNA methylation landscape at base-pair resolution in human neurological disorders (Bisulfite-Seq)
PMID 26784972
Article Title Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns
Author Sanchez-Mut JV, Heyn H, Vidal E, Moran S, Sayols S, Delgado-Morales R, Schultz MD, Ansoleaga B, Garcia-Esparcia P, Pons-Espinal M, de Lagran MM, Dopazo J, Rabano A, Avila J, Dierssen M, Lott I, Ferrer I, Ecker JR, Esteller M
GEO Link https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE57359
Pub Link https://www.ncbi.nlm.nih.gov/pubmed/26784972
FTP Download ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE57nnn/GSE57359/
SRA Run Selector https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA246326
SRP SRP041720

Bed Download

The methylation information with BED format was performed by Bismark and was provided here. Click the options to download the corresponding list.

Differential Methylation

The differential methylation was produced by methylKit, an R package. There would be no result if the experiment design cannot meet the requirement of methylKit.

Genome Browser

You can browse the expression pattern of this item as follows, or click “Full-screen view” to display the patterns of all items stored in BDdb. By this, you are allowed to compare different groups observed by different sequencing approaches.

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