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Basic Information
The table below details the source and basic information of this item.
| Title | Content |
|---|---|
| iBAD ID | iBAD_0000050 |
| Karyotype | Trisomy 21 |
| Type | DNA methylation |
| Diseases | Down syndrome |
| Organism | Homo sapiens |
| Tissue | Brain |
| Cell Line | Cerebral cortex |
| Platform | GPL11154 |
| Accession | GSE57359 |
| GEO Title | Genome-wide profiling of the DNA methylation landscape at base-pair resolution in human neurological disorders (Bisulfite-Seq) |
| PMID | 26784972 |
| Article Title | Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns |
| Author | Sanchez-Mut JV, Heyn H, Vidal E, Moran S, Sayols S, Delgado-Morales R, Schultz MD, Ansoleaga B, Garcia-Esparcia P, Pons-Espinal M, de Lagran MM, Dopazo J, Rabano A, Avila J, Dierssen M, Lott I, Ferrer I, Ecker JR, Esteller M |
| GEO Link | https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE57359 |
| Pub Link | https://www.ncbi.nlm.nih.gov/pubmed/26784972 |
| FTP Download | ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE57nnn/GSE57359/ |
| SRA Run Selector | https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA246326 |
| SRP | SRP041720 |
Bed Download
The methylation information with BED format was performed by Bismark and was provided here. Click the options to download the corresponding list.
Differential Methylation
The differential methylation was produced by methylKit, an R package. There would be no result if the experiment design cannot meet the requirement of methylKit.
Genome Browser
You can browse the expression pattern of this item as follows, or click “Full-screen view” to display the patterns of all items stored in BDdb. By this, you are allowed to compare different groups observed by different sequencing approaches.